Detalhe da pesquisa
1.
Patrolling Alveolar Macrophages Conceal Bacteria from the Immune System to Maintain Homeostasis.
Cell
; 183(1): 110-125.e11, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32888431
2.
A Bispecific Monoclonal Antibody Targeting Psl and PcrV Enhances Neutrophil-Mediated Killing of Pseudomonas aeruginosa in Patients with Bronchiectasis.
Am J Respir Crit Care Med
; 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38754132
3.
Efficacy of a Pseudomonas aeruginosa serogroup O9 vaccine.
Infect Immun
; 91(12): e0024723, 2023 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37991349
4.
Multicomponent Pseudomonas aeruginosa Vaccines Eliciting Th17 Cells and Functional Antibody Responses Confer Enhanced Protection against Experimental Acute Pneumonia in Mice.
Infect Immun
; 90(10): e0020322, 2022 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36069593
5.
Antivirulence Bispecific Monoclonal Antibody-Mediated Protection against Pseudomonas aeruginosa Ventilator-Associated Pneumonia in a Rabbit Model.
Antimicrob Agents Chemother
; 66(2): e0202221, 2022 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34902264
6.
Safety, efficacy, and pharmacokinetics of gremubamab (MEDI3902), an anti-Pseudomonas aeruginosa bispecific human monoclonal antibody, in P. aeruginosa-colonised, mechanically ventilated intensive care unit patients: a randomised controlled trial.
Crit Care
; 26(1): 355, 2022 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36380312
7.
Treatment Efficacy of MEDI3902 in Pseudomonas aeruginosa Bloodstream Infection and Acute Pneumonia Rabbit Models.
Antimicrob Agents Chemother
; 63(8)2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31160288
8.
Humanised effector-null FcγRIIA antibody inhibits immune complex-mediated proinflammatory responses.
Ann Rheum Dis
; 78(2): 228-237, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30459279
9.
The Neutrophilic Response to Pseudomonas Damages the Airway Barrier, Promoting Infection by Klebsiella pneumoniae.
Am J Respir Cell Mol Biol
; 59(6): 745-756, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30109945
10.
MEDI3902 Correlates of Protection against Severe Pseudomonas aeruginosa Pneumonia in a Rabbit Acute Pneumonia Model.
Antimicrob Agents Chemother
; 62(5)2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29483116
11.
Pseudomonas aeruginosa Bacteremic Patients Exhibit Nonprotective Antibody Titers Against Therapeutic Antibody Targets PcrV and Psl Exopolysaccharide.
J Infect Dis
; 213(4): 640-8, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26333940
12.
Synthetic Enterobacterial Common Antigen (ECA) for the Development of a Universal Immunotherapy for Drug-Resistant Enterobacteriaceae.
Angew Chem Int Ed Engl
; 54(37): 10953-7, 2015 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26216389
13.
A novel anti-PcrV antibody providing enhanced protection against Pseudomonas aeruginosa in multiple animal infection models.
Antimicrob Agents Chemother
; 58(8): 4384-91, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24841258
14.
Epitope mapping of monoclonal antibodies using synthetic oligosaccharides uncovers novel aspects of immune recognition of the Psl exopolysaccharide of Pseudomonas aeruginosa.
Chemistry
; 19(51): 17425-31, 2013 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24248772
15.
Differential in vivo labeling with barcoded antibodies allows for simultaneous transcriptomic profiling of airway, lung tissue and intravascular immune cells.
Front Immunol
; 14: 1227175, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38094305
16.
Efficacy of a Pseudomonas aeruginosa Serogroup O9 Vaccine.
bioRxiv
; 2023 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37502855
17.
Early diagnostic BioMARKers in exacerbations of chronic obstructive pulmonary disease: protocol of the exploratory, prospective, longitudinal, single-centre, observational MARKED study.
BMJ Open
; 13(3): e068787, 2023 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36868599
18.
A protein-free vaccine stimulates innate immunity and protects against nosocomial pathogens.
Sci Transl Med
; 15(716): eadf9556, 2023 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37792959
19.
Development and validation of a rabbit model of Pseudomonas aeruginosa non-ventilated pneumonia for preclinical drug development.
Front Cell Infect Microbiol
; 13: 1297281, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38149013
20.
Microbiome Modulation as a Novel Strategy to Treat and Prevent Respiratory Infections.
Antibiotics (Basel)
; 11(4)2022 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35453224