Detalhe da pesquisa
1.
Molecular docking, characterization, ADME/toxicity prediction, and anti-ulcer activity of new quercetin derivatives on indomethacin-induced gastric ulcer in mice.
Toxicol Appl Pharmacol
; 484: 116880, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38447874
2.
Itraconazole, a cytochrome P450 inhibitor, enhanced the efficacy of praziquantel against Schistosoma mansoni infection and alleviated liver injury in mice.
Exp Parasitol
; 239: 108293, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35667394
3.
The ponatinib/gossypol novel combination provides enhanced anticancer activity against murine solid Ehrlich carcinoma via triggering apoptosis and inhibiting proliferation/angiogenesis.
Toxicol Appl Pharmacol
; 432: 115767, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34699866
4.
The phosphodiesterase-4 inhibitor roflumilast impacts Schistosoma mansoni ovipositing in vitro but displays only modest antischistosomal activity in vivo.
Exp Parasitol
; 208: 107793, 2020 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-31711973
5.
Deciphering the enzymatic target of a new family of antischistosomal agents bearing a quinazoline scaffold using complementary computational tools.
J Enzyme Inhib Med Chem
; 35(1): 511-523, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31939312
6.
Bioavailability of paracetamol with/without caffeine in Egyptian patients with hepatitis C virus.
Eur J Clin Pharmacol
; 72(5): 573-82, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26888096
7.
Metabolic profile and hepatoprotective activity of the anthocyanin-rich extract of Hibiscus sabdariffa calyces.
Pharm Biol
; 54(12): 3172-3181, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27564372
8.
Praziquantel in a clay nanoformulation shows more bioavailability and higher efficacy against murine Schistosoma mansoni infection.
Antimicrob Agents Chemother
; 59(6): 3501-8, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25845870
9.
Hepatoprotective and antioxidant activity of Melaleuca styphelioides on carbon tetrachloride-induced hepatotoxicity in mice.
Pharm Biol
; 52(12): 1581-90, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25243881
10.
Potential effect of the medicinal plants Calotropis procera, Ficus elastica and Zingiber officinale against Schistosoma mansoni in mice.
Pharm Biol
; 52(2): 144-50, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24047470
11.
Vildagliptin alleviates liver fibrosis in NASH diabetic rats via modulation of insulin resistance, oxidative stress, and inflammatory cascades.
Life Sci
; 304: 120695, 2022 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35671811
12.
Potential antifibrotic effects of AT1 receptor antagonist, losartan, and/or praziquantel on acute and chronic experimental liver fibrosis induced by Schistosoma mansoni.
Clin Exp Pharmacol Physiol
; 38(10): 695-704, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21762203
13.
Gut microbiota modulation as a promising therapy with metformin in rats with non-alcoholic steatohepatitis: Role of LPS/TLR4 and autophagy pathways.
Eur J Pharmacol
; 887: 173461, 2020 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32758573
14.
A novel praziquantel solid lipid nanoparticle formulation shows enhanced bioavailability and antischistosomal efficacy against murine S. mansoni infection.
Parasit Vectors
; 12(1): 304, 2019 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31208446
15.
Antifibrotic effects of gallic acid on hepatic stellate cells: In vitro and in vivo mechanistic study.
J Tradit Complement Med
; 9(1): 45-53, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-30671365
16.
Screening of a PDE-focused library identifies imidazoles with in vitro and in vivo antischistosomal activity.
Int J Parasitol Drugs Drug Resist
; 9: 35-43, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30669086
17.
Rosmarinic acid attenuates hepatic fibrogenesis via suppression of hepatic stellate cell activation/proliferation and induction of apoptosis.
Asian Pac J Trop Med
; 10(5): 444-453, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28647181
18.
Drug-metabolizing enzymes and praziquantel bioavailability in mice harboring Schistosoma mansoni isolates of different drug susceptibilities.
J Parasitol
; 92(6): 1344-9, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17304818
19.
Effects of rosuvastatin and/or ß-carotene on non-alcoholic fatty liver in rats.
Res Pharm Sci
; 10(4): 275-87, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26600855
20.
Pharmacological and antioxidant actions of garlic and.or onion in non-alcoholic fatty liver disease (NAFLD) in rats.
J Egypt Soc Parasitol
; 44(2): 295-308, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25597144