Detalhe da pesquisa
1.
Polymer-based antibody mimetics (iBodies) target human PD-L1 and function as a potent immune checkpoint blocker.
J Biol Chem
; : 107325, 2024 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38685532
2.
Step-By-Step Standardization of the Bottom-Up Semi-Automated Nanocrystallization of Pharmaceuticals: A Quality By Design and Design of Experiments Joint Approach.
Small
; : e2306054, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38299478
3.
Chemical modification of bradykinin-polymer conjugates for optimum delivery of nanomedicines to tumors.
Nanomedicine
; 57: 102744, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38460653
4.
Therapeutic activity and biodistribution of a nano-sized polymer-dexamethasone conjugate intended for the targeted treatment of rheumatoid arthritis.
Nanomedicine
; 55: 102716, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38738529
5.
HPMA copolymer conjugated 5-aminolevulinic acid exhibits superior efficacy for photodynamic therapy with tumor-responsive and targeting properties.
Nanomedicine
; 48: 102636, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36549553
6.
Dye labeling for optical imaging biases drug carriers' biodistribution and tumor uptake.
Nanomedicine
; 48: 102650, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36623712
7.
The development of a high-affinity conformation-sensitive antibody mimetic using a biocompatible copolymer carrier (iBody).
J Biol Chem
; 297(5): 101342, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34710374
8.
Simultaneous Delivery of Doxorubicin and Protease Inhibitor Derivative to Solid Tumors via Star-Shaped Polymer Nanomedicines Overcomes P-gp- and STAT3-Mediated Chemoresistance.
Biomacromolecules
; 23(6): 2522-2535, 2022 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35584053
9.
Polymer nanomedicines with enzymatically triggered activation: A comparative study of in vitro and in vivo anti-cancer efficacy related to the spacer structure.
Nanomedicine
; 46: 102597, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36064033
10.
Glycopolymers for Efficient Inhibition of Galectin-3: In Vitro Proof of Efficacy Using Suppression of T Lymphocyte Apoptosis and Tumor Cell Migration.
Biomacromolecules
; 21(8): 3122-3133, 2020 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32697592
11.
High-Affinity N-(2-Hydroxypropyl)methacrylamide Copolymers with Tailored N-Acetyllactosamine Presentation Discriminate between Galectins.
Biomacromolecules
; 21(2): 641-652, 2020 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31904940
12.
Intratumoral Distribution and pH-Dependent Drug Release of High Molecular Weight HPMA Copolymer Drug Conjugates Strongly Depend on Specific Tumor Substructure and Microenvironment.
Int J Mol Sci
; 21(17)2020 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32825790
13.
Superior Penetration and Cytotoxicity of HPMA Copolymer Conjugates of Pirarubicin in Tumor Cell Spheroid.
Mol Pharm
; 16(8): 3452-3459, 2019 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31294568
14.
Polymer Cancerostatics Targeted by Recombinant Antibody Fragments to GD2-Positive Tumor Cells.
Biomacromolecules
; 20(1): 412-421, 2019 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30485077
15.
Impact of Polymer-TLR-7/8 Agonist (Adjuvant) Morphology on the Potency and Mechanism of CD8 T Cell Induction.
Biomacromolecules
; 20(2): 854-870, 2019 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30608149
16.
Singlet oxygen phosphorescence detection in vivo identifies PDT-induced anoxia in solid tumors.
Photochem Photobiol Sci
; 18(6): 1304-1314, 2019 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30994640
17.
Bloodstream Stability Predetermines the Antitumor Efficacy of Micellar Polymer-Doxorubicin Drug Conjugates with pH-Triggered Drug Release.
Mol Pharm
; 15(9): 3654-3663, 2018 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29543465
18.
Inhibitor-GCPII Interaction: Selective and Robust System for Targeting Cancer Cells with Structurally Diverse Nanoparticles.
Mol Pharm
; 15(8): 2932-2945, 2018 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29389139
19.
Binding of HSA to Macromolecular pHPMA Based Nanoparticles for Drug Delivery: An Investigation Using Fluorescence Methods.
Langmuir
; 34(27): 7998-8006, 2018 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29949376
20.
N-(2-Hydroxypropyl)methacrylamide-Based Linear, Diblock, and Starlike Polymer Drug Carriers: Advanced Process for Their Simple Production.
Biomacromolecules
; 19(10): 4003-4013, 2018 10 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30180562