Detalhe da pesquisa
1.
Plasma proteomic associations with genetics and health in the UK Biobank.
Nature
; 622(7982): 329-338, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37794186
2.
Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite levels and disease risk.
Am J Hum Genet
; 109(10): 1727-1741, 2022 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36055244
3.
Current Techniques for Complex Phenotypes: GWAS of the Electrocardiogram.
Trends Genet
; 36(12): 897-899, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32980178
4.
Predicting causal genes from psychiatric genome-wide association studies using high-level etiological knowledge.
Mol Psychiatry
; 27(7): 3095-3106, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35411039
5.
An optimal variant to gene distance window derived from an empirical definition of cis and trans protein QTLs.
BMC Bioinformatics
; 23(1): 169, 2022 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35527238
6.
Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci.
BMC Med
; 19(1): 232, 2021 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34503513
7.
ProGeM: a framework for the prioritization of candidate causal genes at molecular quantitative trait loci.
Nucleic Acids Res
; 47(1): e3, 2019 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30239796
8.
An Unbiased Lipid Phenotyping Approach To Study the Genetic Determinants of Lipids and Their Association with Coronary Heart Disease Risk Factors.
J Proteome Res
; 18(6): 2397-2410, 2019 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30887811
9.
GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci.
Hum Mol Genet
; 26(7): 1391-1406, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28199695
10.
LAVAA: a lightweight association viewer across ailments.
Bioinform Adv
; 3(1): vbad018, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36908397
11.
Metabolome-wide Mendelian randomization characterizes heterogeneous and shared causal effects of metabolites on human health.
medRxiv
; 2023 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37425837
12.
The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits.
Cell Metab
; 35(4): 695-710.e6, 2023 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36963395
13.
Integrative analysis of metabolite GWAS illuminates the molecular basis of pleiotropy and genetic correlation.
Elife
; 112022 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36073519
14.
Effector membrane translocation biosensors reveal G protein and ßarrestin coupling profiles of 100 therapeutically relevant GPCRs.
Elife
; 112022 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35302493
15.
Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci.
Nat Commun
; 13(1): 1644, 2022 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35347128
16.
Rare and common genetic determinants of metabolic individuality and their effects on human health.
Nat Med
; 28(11): 2321-2332, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36357675
17.
An open approach to systematically prioritize causal variants and genes at all published human GWAS trait-associated loci.
Nat Genet
; 53(11): 1527-1533, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34711957
18.
Characterising a healthy adult with a rare HAO1 knockout to support a therapeutic strategy for primary hyperoxaluria.
Elife
; 92020 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32207686
19.
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.
Nat Genet
; 52(12): 1314-1332, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33230300
20.
Identification of a novel mitogen-activated protein kinase kinase activation domain recognized by the inhibitor PD 184352.
Mol Cell Biol
; 22(21): 7593-602, 2002 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-12370306