Detalhe da pesquisa
1.
Hypersensitivity to ferroptosis in chromophobe RCC is mediated by a glutathione metabolic dependency and cystine import via solute carrier family 7 member 11.
Proc Natl Acad Sci U S A
; 119(28): e2122840119, 2022 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35867762
2.
Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells.
Proc Natl Acad Sci U S A
; 118(39)2021 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34544857
3.
Impairment of gamma-glutamyl transferase 1 activity in the metabolic pathogenesis of chromophobe renal cell carcinoma.
Proc Natl Acad Sci U S A
; 115(27): E6274-E6282, 2018 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29891694
4.
Tuberous sclerosis complex 2 loss increases lysophosphatidylcholine synthesis in lymphangioleiomyomatosis.
Am J Respir Cell Mol Biol
; 53(1): 33-41, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25780943
5.
Replication stress and mitotic dysfunction in cells expressing simian virus 40 large T antigen.
J Virol
; 87(24): 13179-92, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24067972
6.
TFEB drives mTORC1 hyperactivation and kidney disease in Tuberous Sclerosis Complex.
Nat Commun
; 15(1): 406, 2024 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38195686
7.
The enhanced host-cell permissiveness of human cytomegalovirus is mediated by the Ras signaling pathway.
Biochim Biophys Acta
; 1813(10): 1872-82, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21782855
8.
Mouse phospholipid phosphatase 6 regulates dendritic cell cholesterol, macropinocytosis, and allergen sensitization.
iScience
; 25(10): 105185, 2022 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36238896
9.
Herpesviruses: hijacking the Ras signaling pathway.
Biochim Biophys Acta
; 1803(7): 777-85, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20303365
10.
Quantitative Assessment of Macropinocytosis in mTORC1-Hyperactive Cells using Flow Cytometry.
J Vis Exp
; (174)2021 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34398147
11.
TSC2 Interacts with HDLBP/Vigilin and Regulates Stress Granule Formation.
Mol Cancer Res
; 19(8): 1389-1397, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33888601
12.
TSC2 regulates lysosome biogenesis via a non-canonical RAGC and TFEB-dependent mechanism.
Nat Commun
; 12(1): 4245, 2021 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34253722
13.
Therapeutic Targeting of DGKA-Mediated Macropinocytosis Leads to Phospholipid Reprogramming in Tuberous Sclerosis Complex.
Cancer Res
; 81(8): 2086-2100, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33593821
14.
Histamine signaling and metabolism identify potential biomarkers and therapies for lymphangioleiomyomatosis.
EMBO Mol Med
; 13(9): e13929, 2021 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34378323
15.
Vps34-mediated macropinocytosis in Tuberous Sclerosis Complex 2-deficient cells supports tumorigenesis.
Sci Rep
; 8(1): 14161, 2018 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30242175
16.
Lysosomal regulation of cholesterol homeostasis in tuberous sclerosis complex is mediated via NPC1 and LDL-R.
Oncotarget
; 8(24): 38099-38112, 2017 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28498820
17.
Rapamycin-induced miR-21 promotes mitochondrial homeostasis and adaptation in mTORC1 activated cells.
Oncotarget
; 8(39): 64714-64727, 2017 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29029388
18.
Autophagy : Moving Benchside Promises to Patient Bedsides.
Curr Cancer Drug Targets
; 15(8): 684-702, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26452384
19.
Anticancer effects of the metabolic products of the resveratrol analogue, DMU-212: structural requirements for potency.
Eur J Med Chem
; 46(6): 2586-95, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21497957