Detalhe da pesquisa
1.
CRISPR gene editing in pluripotent stem cells reveals the function of MBNL proteins during human in vitro myogenesis.
Hum Mol Genet
; 31(1): 41-56, 2021 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34312665
2.
Dystrophin Restoration after Adeno-Associated Virus U7-Mediated Dmd Exon Skipping Is Modulated by Muscular Exercise in the Severe D2-Mdx Duchenne Muscular Dystrophy Murine Model.
Am J Pathol
; 192(11): 1604-1618, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36113555
3.
MBNL-dependent impaired development within the neuromuscular system in myotonic dystrophy type 1.
Neuropathol Appl Neurobiol
; 49(1): e12876, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36575942
4.
Comprehensive transcriptome-wide analysis of spliceopathy correction of myotonic dystrophy using CRISPR-Cas9 in iPSCs-derived cardiomyocytes.
Mol Ther
; 30(1): 75-91, 2022 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34371182
5.
Valproic acid reduces muscle susceptibility to contraction-induced functional loss but increases weakness in two murine models of Duchenne muscular dystrophy.
Clin Exp Pharmacol Physiol
; 50(9): 749-756, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37381823
6.
Desmin prevents muscle wasting, exaggerated weakness and fragility, and fatigue in dystrophic mdx mouse.
J Physiol
; 598(17): 3667-3689, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32515007
7.
Genome Editing of Expanded CTG Repeats within the Human DMPK Gene Reduces Nuclear RNA Foci in the Muscle of DM1 Mice.
Mol Ther
; 27(8): 1372-1388, 2019 08 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31253581
8.
Efficient CRISPR/Cas9-mediated editing of trinucleotide repeat expansion in myotonic dystrophy patient-derived iPS and myogenic cells.
Nucleic Acids Res
; 46(16): 8275-8298, 2018 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29947794
9.
Improvement of Dystrophic Muscle Fragility by Short-Term Voluntary Exercise through Activation of Calcineurin Pathway in mdx Mice.
Am J Pathol
; 188(11): 2662-2673, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30142334
10.
Precise small-molecule recognition of a toxic CUG RNA repeat expansion.
Nat Chem Biol
; 13(2): 188-193, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27941760
11.
Dysregulation of Circular RNAs in Myotonic Dystrophy Type 1.
Int J Mol Sci
; 20(8)2019 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31010208
12.
CRISPR/Cas9-Induced (CTGâ CAG)n Repeat Instability in the Myotonic Dystrophy Type 1 Locus: Implications for Therapeutic Genome Editing.
Mol Ther
; 25(1): 24-43, 2017 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28129118
13.
MyoD transcription factor induces myogenesis by inhibiting Twist-1 through miR-206.
J Cell Sci
; 128(19): 3631-45, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26272918
14.
Effect of constitutive inactivation of the myostatin gene on the gain in muscle strength during postnatal growth in two murine models.
Muscle Nerve
; 55(2): 254-261, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27312354
15.
Nuclear protein spreading: implication for pathophysiology of neuromuscular diseases.
Hum Mol Genet
; 23(15): 4125-33, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24659496
16.
High-content screening identifies small molecules that remove nuclear foci, affect MBNL distribution and CELF1 protein levels via a PKC-independent pathway in myotonic dystrophy cell lines.
Hum Mol Genet
; 23(6): 1551-62, 2014 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24179176
17.
Mechanical Overloading Increases Maximal Force and Reduces Fragility in Hind Limb Skeletal Muscle from Mdx Mouse.
Am J Pathol
; 185(7): 2012-24, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26009153
18.
A defective Krab-domain zinc-finger transcription factor contributes to altered myogenesis in myotonic dystrophy type 1.
Hum Mol Genet
; 22(25): 5188-98, 2013 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23922231
19.
Molecular, physiological, and motor performance defects in DMSXL mice carrying >1,000 CTG repeats from the human DM1 locus.
PLoS Genet
; 8(11): e1003043, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23209425
20.
High Risk of Fatal and Nonfatal Venous Thromboembolism in Myotonic Dystrophy.
Circulation
; 138(11): 1169-1171, 2018 09 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30354391