Detalhe da pesquisa
1.
Proteasomal Degradation of the EWS-FLI1 Fusion Protein Is Regulated by a Single Lysine Residue.
J Biol Chem
; 291(52): 26922-26933, 2016 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27875302
2.
Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1.
Nat Chem Biol
; 5(10): 758-64, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19718043
3.
Exposure to community violence is associated with asthma hospitalizations and emergency department visits.
J Allergy Clin Immunol
; 126(3): 552-7, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20816190
4.
Regulation of the interaction between protein kinase C-related protein kinase 2 (PRK2) and its upstream kinase, 3-phosphoinositide-dependent protein kinase 1 (PDK1).
J Biol Chem
; 284(44): 30318-27, 2009 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-19723632
5.
Alternative AKT2 splicing produces protein lacking the hydrophobic motif regulatory region.
PLoS One
; 15(11): e0242819, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33253205
6.
USP19 deubiquitinates EWS-FLI1 to regulate Ewing sarcoma growth.
Sci Rep
; 9(1): 951, 2019 01 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30700749
7.
Validation of extracellular ligand-receptor interactions by Flow-TriCEPS.
BMC Res Notes
; 11(1): 863, 2018 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30518414
8.
PI3K/AKT signaling modulates transcriptional expression of EWS/FLI1 through specificity protein 1.
Oncotarget
; 6(30): 28895-910, 2015 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26336820
9.
PLK1 phosphorylates PAX3-FOXO1, the inhibition of which triggers regression of alveolar Rhabdomyosarcoma.
Cancer Res
; 75(1): 98-110, 2015 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25398439
10.
Molecular mechanism of regulation of the atypical protein kinase C by N-terminal domains and an allosteric small compound.
Chem Biol
; 21(6): 754-65, 2014 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24836908
11.
Use of a fluorescent ATP analog to probe the allosteric conformational change in the active site of the protein kinase PDK1.
Methods Mol Biol
; 928: 133-41, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22956138
12.
2-(3-Oxo-1,3-diphenylpropyl)malonic acids as potent allosteric ligands of the PIF pocket of phosphoinositide-dependent kinase-1: development and prodrug concept.
J Med Chem
; 55(22): 9817-30, 2012 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23106316
13.
Substrate-selective inhibition of protein kinase PDK1 by small compounds that bind to the PIF-pocket allosteric docking site.
Chem Biol
; 19(9): 1152-63, 2012 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22999883
14.
Selectivity and delignification kinetics for oxidative short-term lime pretreatment of poplar wood, Part I: Constant-pressure.
Biotechnol Prog
; 27(4): 976-85, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21692196
15.
4-benzimidazolyl-3-phenylbutanoic acids as novel PIF-pocket-targeting allosteric inhibitors of protein kinase PKCζ.
J Med Chem
; 54(19): 6714-23, 2011 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21863889
16.
Allosteric regulation of protein kinase PKCζ by the N-terminal C1 domain and small compounds to the PIF-pocket.
Chem Biol
; 18(11): 1463-73, 2011 Nov 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-22118680
17.
Selectivity and delignification kinetics for oxidative and nonoxidative lime pretreatment of poplar wood, part III: long-term.
Biotechnol Prog
; 26(6): 1685-94, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20878719
18.
Allosteric activation of the protein kinase PDK1 with low molecular weight compounds.
EMBO J
; 25(23): 5469-80, 2006 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-17110931