Detalhe da pesquisa
1.
Animal models for COVID-19.
Nature
; 586(7830): 509-515, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32967005
2.
A Microengineered Airway Lung Chip Models Key Features of Viral-induced Exacerbation of Asthma.
Am J Respir Cell Mol Biol
; 63(5): 591-600, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32706623
3.
Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro.
Nat Methods
; 13(2): 151-7, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26689262
4.
Integrated in vitro models for hepatic safety and metabolism: evaluation of a human Liver-Chip and liver spheroid.
Arch Toxicol
; 93(4): 1021-1037, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30915487
5.
Assessment of whole blood thrombosis in a microfluidic device lined by fixed human endothelium.
Biomed Microdevices
; 18(4): 73, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27464497
6.
A novel organ-chip system emulates three-dimensional architecture of the human epithelia and the mechanical forces acting on it.
Biomaterials
; 275: 120957, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34130145
7.
Modeling alpha-synuclein pathology in a human brain-chip to assess blood-brain barrier disruption.
Nat Commun
; 12(1): 5907, 2021 10 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34625559
8.
A Novel Microphysiological Colon Platform to Decipher Mechanisms Driving Human Intestinal Permeability.
Cell Mol Gastroenterol Hepatol
; 12(5): 1719-1741, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34284165
9.
Human immunocompetent Organ-on-Chip platforms allow safety profiling of tumor-targeted T-cell bispecific antibodies.
Elife
; 102021 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34378534
10.
Organs-on-Chips in Clinical Pharmacology: Putting the Patient Into the Center of Treatment Selection and Drug Development.
Clin Pharmacol Ther
; 107(1): 181-185, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31758803
11.
Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model.
Elife
; 92020 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31933478
12.
Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development
ALTEX
; 37(3): 365-394, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32113184
13.
Evaluation of multiple in vitro systems for assessment of CYP3A4 induction in drug discovery: human hepatocytes, pregnane X receptor reporter gene, and Fa2N-4 and HepaRG cells.
Drug Metab Dispos
; 37(6): 1259-68, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19307295
14.
Bone-chip system to monitor osteogenic differentiation using optical imaging.
Microfluid Nanofluidics
; 23(8)2019 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32296299
15.
Introducing an automated high content confocal imaging approach for Organs-on-Chips.
Lab Chip
; 19(3): 410-421, 2019 01 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-30663729
16.
Reproducing human and cross-species drug toxicities using a Liver-Chip.
Sci Transl Med
; 11(517)2019 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31694927
17.
Optimizing drug discovery by Investigative Toxicology: Current and future trends.
ALTEX
; 36(2): 289-313, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30570669
18.
Enhanced Utilization of Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Using Microengineered Chips.
Cell Mol Gastroenterol Hepatol
; 5(4): 669-677.e2, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29930984
19.
Human iPSC-Derived Endothelial Cells and Microengineered Organ-Chip Enhance Neuronal Development.
Stem Cell Reports
; 10(4): 1222-1236, 2018 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29576540
20.
Organ-on-Chip Recapitulates Thrombosis Induced by an anti-CD154 Monoclonal Antibody: Translational Potential of Advanced Microengineered Systems.
Clin Pharmacol Ther
; 104(6): 1240-1248, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29484632