Detalhe da pesquisa
1.
Comparative Evaluation of Dissolution Performance in a USP 2 Setup and Alternative Stirrers and Vessel Designs: A Systematic Computational Investigation.
Mol Pharm
; 21(5): 2406-2414, 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38639477
2.
Digitalizing the TIM-1 Model Using Computational ApproachesâPart Two: Digital TIM-1 Model in GastroPlus.
Mol Pharm
; 20(11): 5429-5439, 2023 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37878668
3.
Digitalizing the TIM-1 Model using Computational Approaches-Part One: TIM-1 Data Explorer.
Mol Pharm
; 20(11): 5416-5428, 2023 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37878746
4.
Effect of Food and a Proton-Pump Inhibitor on the Absorption of Encorafenib: An In Vivo-In Vitro-In Silico Approach.
Mol Pharm
; 20(5): 2589-2599, 2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37037186
5.
Favipiravir at high doses has potent antiviral activity in SARS-CoV-2-infected hamsters, whereas hydroxychloroquine lacks activity.
Proc Natl Acad Sci U S A
; 117(43): 26955-26965, 2020 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33037151
6.
Exploring the Predictive Power of the In Situ Perfusion Technique towards Drug Absorption: Theory, Practice, and Applications.
Mol Pharm
; 19(3): 749-762, 2022 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35188394
7.
Haematoma evacuation in cerebellar intracerebral haemorrhage: systematic review.
J Neurol Neurosurg Psychiatry
; 91(1): 82-87, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31848229
8.
Translational Modeling Strategies for Orally Administered Drug Products: Academic, Industrial and Regulatory Perspectives.
Pharm Res
; 37(6): 95, 2020 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32405699
9.
Voices in Molecular Pharmaceutics: Meet Dr. Bart Hens, A Sociable Scientist Focusing on Multidisciplinary Connections to Unravel the Gaps of Oral Drug Behavior in the Human Gastrointestinal Tract.
Mol Pharm
; 20(12): 5952-5953, 2023 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37938021
10.
Mass Transport Analysis of the Enhanced Buffer Capacity of the Bicarbonate-CO2 Buffer in a Phase-Heterogenous System: Physiological and Pharmaceutical Significance.
Mol Pharm
; 15(11): 5291-5301, 2018 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30362350
11.
Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans-Part 2: Fed State.
Mol Pharm
; 15(12): 5468-5478, 2018 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30417648
12.
Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans-Part 1: Fasted State Conditions.
Mol Pharm
; 15(12): 5454-5467, 2018 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30372084
13.
In Silico Modeling Approach for the Evaluation of Gastrointestinal Dissolution, Supersaturation, and Precipitation of Posaconazole.
Mol Pharm
; 14(12): 4321-4333, 2017 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28817288
14.
Low Buffer Capacity and Alternating Motility along the Human Gastrointestinal Tract: Implications for in Vivo Dissolution and Absorption of Ionizable Drugs.
Mol Pharm
; 14(12): 4281-4294, 2017 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28737409
15.
Drug disposition before and after gastric bypass: fenofibrate and posaconazole.
Br J Clin Pharmacol
; 82(5): 1325-1332, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27367040
16.
Can in vitro/in silico tools improve colonic concentration estimations for oral extended-release formulations? A case study with upadacitinib.
J Control Release
; 370: 182-194, 2024 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38641022
17.
Acute care bundles should be used for patients with intracerebral haemorrhage: An expert consensus statement.
Eur Stroke J
; 9(2): 295-302, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38149323
18.
Dissolution Challenges Associated with the Surface pH of Drug Particles: Integration into Mechanistic Oral Absorption Modeling.
AAPS J
; 24(1): 17, 2022 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34982285
19.
Challenges and Strategies for Solubility Measurements and Dissolution Method Development for Amorphous Solid Dispersion Formulations.
AAPS J
; 25(1): 11, 2022 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36513860
20.
Leveraging Oral Drug Development to a Next Level: Impact of the IMI-Funded OrBiTo Project on Patient Healthcare.
Front Med (Lausanne)
; 8: 480706, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33748152