Detalhe da pesquisa
1.
Induction of dopaminergic neurons for neuronal subtype-specific modeling of psychiatric disease risk.
Mol Psychiatry
; 28(5): 1970-1982, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34493831
2.
Integration of CRISPR-engineering and hiPSC-based models of psychiatric genomics.
Mol Cell Neurosci
; 107: 103532, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32712198
3.
Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells.
Methods
; 101: 113-24, 2016 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26626326
4.
Activity-Dependent Transcriptional Program in NGN2+ Neurons Enriched for Genetic Risk for Brain-Related Disorders.
Biol Psychiatry
; 95(2): 187-198, 2024 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37454787
5.
Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers.
Nat Cancer
; 5(1): 66-84, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38151625
6.
TGF-ß-activated kinase 1 (TAK1) and apoptosis signal-regulating kinase 1 (ASK1) interact with the promyogenic receptor Cdo to promote myogenic differentiation via activation of p38MAPK pathway.
J Biol Chem
; 287(15): 11602-15, 2012 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22337877
7.
Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons.
STAR Protoc
; 2(2): 100580, 2021 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34151300
8.
Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease.
Neuron
; 109(2): 257-272.e14, 2021 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33238137
9.
ASCL1- and DLX2-induced GABAergic neurons from hiPSC-derived NPCs.
J Neurosci Methods
; 334: 108548, 2020 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32065989
10.
Synergistic effects of common schizophrenia risk variants.
Nat Genet
; 51(10): 1475-1485, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31548722
11.
Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk.
Science
; 362(6420)2018 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30545851
12.
Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes.
Stem Cell Reports
; 9(2): 615-628, 2017 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28757163
13.
The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain.
Nat Genet
; 49(8): 1239-1250, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28671686
14.
From "directed differentiation" to "neuronal induction": modeling neuropsychiatric disease.
Biomark Insights
; 10(Suppl 1): 31-41, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26045654
15.
Characterization of molecular and cellular phenotypes associated with a heterozygous CNTNAP2 deletion using patient-derived hiPSC neural cells.
NPJ Schizophr
; 12015 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26985448
16.
Cdo suppresses canonical Wnt signalling via interaction with Lrp6 thereby promoting neuronal differentiation.
Nat Commun
; 5: 5455, 2014 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25406935
17.
Dual functions of highly potent graphene derivative-poly-L-lysine composites to inhibit bacteria and support human cells.
ACS Nano
; 6(8): 7151-61, 2012 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22845739
18.
Gas1 cooperates with Cdo and promotes myogenic differentiation via activation of p38MAPK.
Cell Signal
; 23(12): 2021-9, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21820049
19.
Cdo interacts with APPL1 and activates Akt in myoblast differentiation.
Mol Biol Cell
; 21(14): 2399-411, 2010 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20484574