Detalhe da pesquisa
1.
Binge Drinking: Macropinocytosis Promotes Tumorigenic Growth of RAS-Mutant Cancers.
Trends Biochem Sci
; 45(6): 459-461, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32413322
2.
Oncogenic KRAS G12C: Kinetic and redox characterization of covalent inhibition.
J Biol Chem
; 298(8): 102186, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35753348
3.
KRASG12R-Independent Macropinocytosis in Pancreatic Cancer.
Subcell Biochem
; 98: 205-221, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35378710
4.
Copper is required for oncogenic BRAF signalling and tumorigenesis.
Nature
; 509(7501): 492-6, 2014 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24717435
5.
RAS isoforms and mutations in cancer at a glance.
J Cell Sci
; 129(7): 1287-92, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26985062
6.
HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer.
Cell Death Differ
; 2024 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38802657
7.
RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling.
Sci Signal
; 16(816): eadg5289, 2023 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38113333
8.
Not all RAS mutations are equal: A detailed review of the functional diversity of RAS hot spot mutations.
Adv Cancer Res
; 153: 29-61, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35101234
9.
Identification of the nucleotide-free state as a therapeutic vulnerability for inhibition of selected oncogenic RAS mutants.
Cell Rep
; 38(6): 110322, 2022 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35139380
10.
Concurrent Inhibition of ERK and Farnesyltransferase Suppresses the Growth of HRAS Mutant Head and Neck Squamous Cell Carcinoma.
Mol Cancer Ther
; 21(5): 762-774, 2022 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35247914
11.
Functional and biological heterogeneity of KRASQ61 mutations.
Sci Signal
; 15(746): eabn2694, 2022 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35944066
12.
STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer.
Life Sci Alliance
; 5(11)2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35803738
13.
Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition.
Cell Rep
; 35(13): 109291, 2021 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34192548
14.
Author Correction: Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer.
Nat Med
; 26(6): 982, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32483362
15.
Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer.
Cancer Discov
; 10(1): 104-123, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31649109
16.
Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer.
Cancer Cell
; 38(2): 198-211.e8, 2020 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32559497
17.
RAS Mutations Are Not Created Equal.
Cancer Discov
; 9(6): 696-698, 2019 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-31160330
18.
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer.
Nat Med
; 25(4): 628-640, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30833752
19.
Evaluation of the selectivity and sensitivity of isoform- and mutation-specific RAS antibodies.
Sci Signal
; 10(498)2017 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28951536
20.
Selective Targeting of the KRAS G12C Mutant: Kicking KRAS When It's Down.
Cancer Cell
; 29(3): 251-253, 2016 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26977877