Detalhe da pesquisa
1.
BPR1J373, a novel multitargeted kinase inhibitor, effectively suppresses the growth of gastrointestinal stromal tumor.
Cancer Sci
; 109(11): 3591-3601, 2018 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-30142229
2.
Targeting Tumor Associated Phosphatidylserine with New Zinc Dipicolylamine-Based Drug Conjugates.
Bioconjug Chem
; 28(7): 1878-1892, 2017 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28581724
3.
Resistance studies of a dithiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems.
Antimicrob Agents Chemother
; 57(2): 723-33, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23165461
4.
Synthesis of acylguanidine zanamivir derivatives as neuraminidase inhibitors and the evaluation of their bio-activities.
Org Biomol Chem
; 11(24): 3943-8, 2013 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23695381
5.
Development of Furanopyrimidine-Based Orally Active Third-Generation EGFR Inhibitors for the Treatment of Non-Small Cell Lung Cancer.
J Med Chem
; 66(4): 2566-2588, 2023 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36749735
6.
Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor.
Antimicrob Agents Chemother
; 56(1): 44-53, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22006008
7.
Synthesis and biological evaluation of 2-amino-1-thiazolyl imidazoles as orally active anticancer agents.
Invest New Drugs
; 30(1): 164-75, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20890633
8.
Acyl-Coenzyme A Synthetase Long-Chain Family Member 4 Is Involved in Viral Replication Organelle Formation and Facilitates Virus Replication via Ferroptosis.
mBio
; 13(1): e0271721, 2022 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35038927
9.
Synthesis and Evaluation of Small Molecule Drug Conjugates Harnessing Thioester-Linked Maytansinoids.
Pharmaceutics
; 14(7)2022 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35890212
10.
Targeting the Phosphatidylserine-Immune Checkpoint with a Small-Molecule Maytansinoid Conjugate.
J Med Chem
; 65(19): 12802-12824, 2022 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36153998
11.
Isatin-ß-thiosemicarbazones as potent herpes simplex virus inhibitors.
Bioorg Med Chem Lett
; 21(7): 1948-52, 2011 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21356589
12.
Colloidal Assemblies Composed of Polymeric Micellar/Emulsified Systems Integrate Cancer Therapy Combining a Tumor-Associated Antigen Vaccine and Chemotherapeutic Regimens.
Nanomaterials (Basel)
; 11(7)2021 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34361230
13.
Repurposing old drugs as antiviral agents for coronaviruses.
Biomed J
; 43(4): 368-374, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32563698
14.
Artificial intelligence approach fighting COVID-19 with repurposing drugs.
Biomed J
; 43(4): 355-362, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32426387
15.
Design, synthesis, and anti-HCV activity of thiourea compounds.
Bioorg Med Chem Lett
; 19(7): 1950-5, 2009 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19251415
16.
Design and synthesis of indole, 2,3-dihydro-indole, and 3,4-dihydro-2H-quinoline-1-carbothioic acid amide derivatives as novel HCV inhibitors.
Bioorg Med Chem Lett
; 19(15): 4134-8, 2009 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19539472
17.
Design and efficient synthesis of novel arylthiourea derivatives as potent hepatitis C virus inhibitors.
Bioorg Med Chem Lett
; 19(21): 6063-8, 2009 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19796940
18.
Endothelial-mesenchymal transition harnesses HSP90α-secreting M2-macrophages to exacerbate pancreatic ductal adenocarcinoma.
J Hematol Oncol
; 12(1): 138, 2019 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31847880
19.
A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virus.
Eur J Med Chem
; 167: 245-268, 2019 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30772607
20.
Identification of Novel Anti-Liver Cancer Small Molecules with Better Therapeutic Index than Sorafenib via Zebrafish Drug Screening Platform.
Cancers (Basel)
; 11(6)2019 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31141996