Detalhe da pesquisa
1.
MK-5204: An orally active ß-1,3-glucan synthesis inhibitor.
Bioorg Med Chem Lett
; 30(17): 127357, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32738971
2.
Arginine residues on the opposite side of the active site stimulate the catalysis of ribosome depurination by ricin A chain by interacting with the P-protein stalk.
J Biol Chem
; 288(42): 30270-30284, 2013 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24003229
3.
Development of a quantitative RT-PCR assay to examine the kinetics of ribosome depurination by ribosome inactivating proteins using Saccharomyces cerevisiae as a model.
RNA
; 17(1): 201-10, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21098653
4.
Synthesis and antifungal evaluation of pentyloxyl-diphenylisoxazoloyl pneumocandins and echinocandins.
Bioorg Med Chem Lett
; 23(11): 3253-6, 2013 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23623416
5.
Isolation, structure, and biological activity of Phaeofungin, a cyclic lipodepsipeptide from a Phaeosphaeria sp. Using the Genome-Wide Candida albicans Fitness Test.
J Nat Prod
; 76(3): 334-45, 2013 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23259972
6.
Synthesis and biological evaluation of antifungal derivatives of enfumafungin as orally bioavailable inhibitors of ß-1,3-glucan synthase.
Bioorg Med Chem Lett
; 22(22): 6811-6, 2012 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22672801
7.
Isolation, structure, and biological activities of Fellutamides C and D from an undescribed Metulocladosporiella (Chaetothyriales) using the genome-wide Candida albicans fitness test.
J Nat Prod
; 74(8): 1721-30, 2011 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21761939
8.
Differential Aspergillus lentulus echinocandin susceptibilities are Fksp independent.
Antimicrob Agents Chemother
; 54(12): 4992-8, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20855747
9.
PAP inhibitor with in vivo efficacy identified by Candida albicans genetic profiling of natural products.
Chem Biol
; 15(4): 363-74, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18420143
10.
Isolation and structure elucidation of parnafungins C and D, isoxazolidinone-containing antifungal natural products.
Bioorg Med Chem Lett
; 19(4): 1224-7, 2009 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19147347
11.
Isolation, structure and biological activity of phomafungin, a cyclic lipodepsipeptide from a widespread tropical Phoma sp.
Bioorg Med Chem
; 17(3): 1361-9, 2009 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19112025
12.
Isolation, structure elucidation, and biological activity of virgineone from Lachnum Wirgineum using the genome-wide Candida albicans fitness test.
J Nat Prod
; 72(1): 136-41, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19115836
13.
Distribution of the antifungal agents sordarins across filamentous fungi.
Mycol Res
; 113(Pt 6-7): 754-70, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19249360
14.
Chemical Genomics-Based Antifungal Drug Discovery: Targeting Glycosylphosphatidylinositol (GPI) Precursor Biosynthesis.
ACS Infect Dis
; 1(1): 59-72, 2015 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26878058
15.
Common pharmacophore of structurally distinct small-molecule inhibitors of intracellular retrograde trafficking of ribosome inactivating proteins.
Sci Rep
; 3: 3397, 2013 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-24292269
16.
Chemical structure of Retro-2, a compound that protects cells against ribosome-inactivating proteins.
Sci Rep
; 2: 631, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22953052
17.
Small-molecule inhibitor leads of ribosome-inactivating proteins developed using the doorstop approach.
PLoS One
; 6(3): e17883, 2011 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21455295
18.
Acquired echinocandin resistance in a Candida krusei isolate due to modification of glucan synthase.
Antimicrob Agents Chemother
; 51(5): 1876-8, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17325225
19.
Caspofungin susceptibility in Aspergillus and non-Aspergillus molds: inhibition of glucan synthase and reduction of beta-D-1,3 glucan levels in culture.
Antimicrob Agents Chemother
; 50(6): 2214-6, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16723587