Detalhe da pesquisa
1.
Better Peptides via Chemical Glycosylation: Somatostatin Analogues Having a Human Complex-Type N-Glycan with Improved Drug Properties.
Chemistry
; 29(31): e202300111, 2023 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36945747
2.
Spontaneously Cleavable Glycosylated Linker Capable of Extended Release of Its Conjugated Peptide.
Chem Pharm Bull (Tokyo)
; 67(3): 236-243, 2019 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30305463
3.
Manganese ion concentration affects production of human core 3 O-glycan in Saccharomyces cerevisiae.
Biochim Biophys Acta
; 1860(9): 1809-20, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27259834
4.
Neuropeptide Y5 receptor antagonism does not induce clinically meaningful weight loss in overweight and obese adults.
Cell Metab
; 4(4): 275-82, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17011500
5.
Discovery of novel phenylpyridone derivatives as potent and selective MCH1R antagonists.
Bioorg Med Chem
; 19(2): 883-93, 2011 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21190859
6.
Discovery of novel phenethylpyridone derivatives as potent melanin-concentrating hormone 1 receptor antagonists.
Bioorg Med Chem Lett
; 19(17): 5186-90, 2009 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19632840
7.
Discovery of substituted 2,4,4-triarylimidazoline derivatives as potent and selective neuropeptide Y Y5 receptor antagonists.
Bioorg Med Chem Lett
; 19(6): 1670-4, 2009 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19233647
8.
Identification and characterization of a selective radioligand for melanin-concentrating hormone 1-receptor (MCH1R).
Bioorg Med Chem Lett
; 19(10): 2835-9, 2009 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19361985
9.
Identification of 2-aminobenzimidazoles as potent melanin-concentrating hormone 1-receptor (MCH1R) antagonists.
Bioorg Med Chem Lett
; 19(13): 3568-72, 2009 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19457661
10.
Discovery of imidazo[1,2-a]pyridines as potent MCH1R antagonists.
Bioorg Med Chem Lett
; 19(16): 4589-93, 2009 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19615899
11.
Identification of positron emission tomography ligands for NPY Y5 receptors in the brain.
Bioorg Med Chem Lett
; 19(18): 5436-9, 2009 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19679469
12.
Identification of novel and orally active spiroindoline NPY Y5 receptor antagonists.
Bioorg Med Chem Lett
; 19(6): 1564-8, 2009 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19243937
13.
Discovery of novel spiro-piperidine derivatives as highly potent and selective melanin-concentrating hormone 1 receptor antagonists.
Bioorg Med Chem Lett
; 19(11): 3072-7, 2009 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19403308
14.
Aryl urea derivatives of spiropiperidines as NPY Y5 receptor antagonists.
Bioorg Med Chem Lett
; 19(13): 3511-6, 2009 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19464889
15.
Discovery of novel diarylketoxime derivatives as selective and orally active melanin-concentrating hormone 1 receptor antagonists.
Bioorg Med Chem Lett
; 19(18): 5339-45, 2009 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19683441
16.
Novel orally active NPY Y5 receptor antagonists: Synthesis and structure-activity relationship of spiroindoline class compounds.
Bioorg Med Chem
; 17(14): 5015-26, 2009 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19525116
17.
Discovery of pyridone-containing imidazolines as potent and selective inhibitors of neuropeptide Y Y5 receptor.
Bioorg Med Chem
; 17(16): 6106-22, 2009 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19616955
18.
Discovery of trans-N-[1-(2-fluorophenyl)-3-pyrazolyl]-3-oxospiro[6-azaisobenzofuran-1(3H),1'-cyclohexane]-4'-carboxamide, a potent and orally active neuropeptide Y Y5 receptor antagonist.
Bioorg Med Chem
; 17(19): 6971-82, 2009 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19720539
19.
Distinctive role of central histamine H3 receptor in various orexigenic pathways.
Eur J Pharmacol
; 579(1-3): 229-32, 2008 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-18037404
20.
Syntheses and structure-activity relationships of novel, potent, and selective trans-2-[3-oxospiro[isobenzofuran-1(3H),1'-cyclohexan]-4'-yl]benzimidazole NPY Y5 receptor antagonists.
Bioorg Med Chem Lett
; 18(18): 4997-5001, 2008 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18752943