Detalhe da pesquisa
1.
Valproic acid disables the Nrf2 anti-oxidant response in acute myeloid leukaemia cells enhancing reactive oxygen species-mediated killing.
Br J Cancer
; 126(2): 275-286, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34686779
2.
The 'known-knowns', and 'known-unknowns' of extracellular Nm23-H1/NDPK proteins.
Lab Invest
; 98(5): 602-608, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29339833
3.
Pathogen and human NDPK-proteins promote AML cell survival via monocyte NLRP3-inflammasome activation.
PLoS One
; 18(7): e0288162, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37418424
4.
Does the pursuit of scientific excellence serve or hamper translational medical research: an historical perspective from hematological malignancies.
Blood Cancer J
; 12(10): 142, 2022 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36202796
5.
Novel intravesical therapeutics in the treatment of non-muscle invasive bladder cancer: Horizon scanning.
Front Surg
; 9: 912438, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35959122
6.
Targeting Asparagine and Serine Metabolism in Germinal Centre-Derived B Cells Non-Hodgkin Lymphomas (B-NHL).
Cells
; 10(10)2021 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34685569
7.
Combined bezafibrate, medroxyprogesterone acetate and valproic acid treatment inhibits osteosarcoma cell growth without adversely affecting normal mesenchymal stem cells.
Biosci Rep
; 41(1)2021 01 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33289496
8.
The Hyperlipidaemic Drug Fenofibrate Significantly Reduces Infection by SARS-CoV-2 in Cell Culture Models.
Front Pharmacol
; 12: 660490, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34421587
9.
The anti-tumour activity of DNA methylation inhibitor 5-aza-2'-deoxycytidine is enhanced by the common analgesic paracetamol through induction of oxidative stress.
Cancer Lett
; 501: 172-186, 2021 03 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-33359448
10.
Elevated NCOR1 disrupts PPARalpha/gamma signaling in prostate cancer and forms a targetable epigenetic lesion.
Carcinogenesis
; 31(9): 1650-60, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20466759
11.
Combined bezafibrate and medroxyprogesterone acetate have efficacy without haematological toxicity in elderly and relapsed acute myeloid leukaemia (AML).
Br J Haematol
; 149(1): 65-9, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20067564
12.
Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy.
BMC Cell Biol
; 10: 31, 2009 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-19400951
13.
Bezafibrate and medroxyprogesterone acetate in resistant and relapsed endemic Burkitt lymphoma in Malawi; an open-label, single-arm, phase 2 study (ISRCTN34303497).
Br J Haematol
; 164(6): 888-90, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24266453
14.
Elevated FOSB-expression; a potential marker of valproate sensitivity in AML.
Br J Haematol
; 144(3): 332-41, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19036090
15.
The aldo-keto reductase AKR1C3 contributes to 7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol mediated oxidative DNA damage in myeloid cells: implications for leukemogenesis.
Mutat Res
; 662(1-2): 67-74, 2009 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-19162045
16.
A framework for tracer-based metabolism in mammalian cells by NMR.
Sci Rep
; 9(1): 2520, 2019 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30792403
17.
Probing the action of a novel anti-leukaemic drug therapy at the single cell level using modern vibrational spectroscopy techniques.
Sci Rep
; 7(1): 2649, 2017 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28572622
18.
Knockdown of AKR1C3 exposes a potential epigenetic susceptibility in prostate cancer cells.
J Steroid Biochem Mol Biol
; 155(Pt A): 47-55, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26429394
19.
Malonate as a ROS product is associated with pyruvate carboxylase activity in acute myeloid leukaemia cells.
Cancer Metab
; 4: 15, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27493727
20.
Establishing the Bladder Cancer Research Centre at the University of Birmingham.
Nat Rev Urol
; 18(6): 318-320, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33712734