Detalhe da pesquisa
1.
Correction: Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia.
PLoS Biol
; 20(5): e3001621, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35507910
2.
Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia.
PLoS Biol
; 19(12): e3001480, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34914695
3.
Coding and Noncoding Variation in LRRK2 and Parkinson's Disease Risk.
Mov Disord
; 37(1): 95-105, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34542912
4.
Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia.
Brain
; 143(1): 234-248, 2020 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31755958
5.
Differences in Stability, Activity and Mutation Effects Between Human and Mouse Leucine-Rich Repeat Kinase 2.
Neurochem Res
; 44(6): 1446-1459, 2019 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-30291536
6.
The G2385R risk factor for Parkinson's disease enhances CHIP-dependent intracellular degradation of LRRK2.
Biochem J
; 474(9): 1547-1558, 2017 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28320779
7.
The function of orthologues of the human Parkinson's disease gene LRRK2 across species: implications for disease modelling in preclinical research.
Biochem J
; 473(3): 221-32, 2016 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26811536
8.
Heparin-binding peptide as a novel affinity tag for purification of recombinant proteins.
Protein Expr Purif
; 126: 93-103, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27235575
9.
Comparisons of interfacial Phe, Tyr, and Trp residues as determinants of orientation and dynamics for GWALP transmembrane peptides.
Biochemistry
; 53(22): 3637-45, 2014 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24829070
10.
Evaluating N-benzylgalactonoamidines as putative transition state analogs for ß-galactoside hydrolysis.
Org Biomol Chem
; 12(17): 2792-800, 2014 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24668069
11.
Intracranial hematolymphoid malignancies: A case series with molecular characterization.
Clin Neurol Neurosurg
; 233: 107928, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37573681
12.
Divergent patterns of healthy aging across human brain regions at single-cell resolution reveal links to neurodegenerative disease.
bioRxiv
; 2023 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37577533
13.
Association of a common genetic variant with Parkinson's disease is mediated by microglia.
Sci Transl Med
; 14(655): eabp8869, 2022 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35895835
14.
Generation of fourteen isogenic cell lines for Parkinson's disease-associated leucine-rich repeat kinase (LRRK2).
Stem Cell Res
; 53: 102354, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34087985
15.
Genetic analysis of amyotrophic lateral sclerosis identifies contributing pathways and cell types.
Sci Adv
; 7(3)2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33523907
16.
LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies.
EMBO Mol Med
; 13(9): e14745, 2021 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34309222
17.
Pathways of protein synthesis and degradation in PD pathogenesis.
Prog Brain Res
; 252: 217-270, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32247365
18.
Characteristics and career outcomes of Neurosurgery Research and Education Foundation research fellowship recipients.
J Neurosurg
; 132(3): 802-808, 2019 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30738408
19.
Use of a Modified STROOP Test to Assess Color Discrimination Deficit in Parkinson's Disease.
Front Neurol
; 9: 765, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30258399
20.
Hexokinases link DJ-1 to the PINK1/parkin pathway.
Mol Neurodegener
; 12(1): 70, 2017 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28962651