1.
J Org Chem
; 89(9): 6602-6606, 2024 May 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38635314
RESUMO
Oxidation of 2-furylaninlies with m-CPBA followed by treatment with a base provides access to functionalized indolin-3-ones. The designed oxidative transformation utilizes an underassessed chemical behavior of furyl-containing amines to form a C-N bond via engaging a ß-carbon atom of the furan core upon a ring-forming step, thereby providing an alternative disconnection toward nitrogen-containing heterocycles.