Detalhe da pesquisa
1.
Targeted ultra-deep sequencing of a South African Bantu-speaking cohort to comprehensively map and characterize common and novel variants in 65 pharmacologically-related genes.
Pharmacogenet Genomics
; 29(7): 167-178, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31162291
2.
UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria.
Antimicrob Agents Chemother
; 62(9)2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29941635
3.
Potent Plasmodium falciparum gametocytocidal compounds identified by exploring the kinase inhibitor chemical space for dual active antimalarials.
J Antimicrob Chemother
; 73(5): 1279-1290, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29420756
4.
In vitro anti-malarial interaction and gametocytocidal activity of cryptolepine.
Malar J
; 16(1): 496, 2017 12 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29282057
5.
Nowhere to hide: interrogating different metabolic parameters of Plasmodium falciparum gametocytes in a transmission blocking drug discovery pipeline towards malaria elimination.
Malar J
; 14: 213, 2015 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25994518
6.
Erratum for Brunschwig et al., "UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria".
Antimicrob Agents Chemother
; 62(11)2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30355750
7.
Thermo-responsive non-woven scaffolds for "smart" 3D cell culture.
Biotechnol Bioeng
; 109(8): 2147-58, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22367720
8.
In vitro anti-plasmodial activity of Dicoma anomala subsp. gerrardii (Asteraceae): identification of its main active constituent, structure-activity relationship studies and gene expression profiling.
Malar J
; 10: 295, 2011 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21985233
9.
Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box.
Nat Commun
; 12(1): 269, 2021 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33431834
10.
Identification and Profiling of a Novel Diazaspiro[3.4]octane Chemical Series Active against Multiple Stages of the Human Malaria Parasite Plasmodium falciparum and Optimization Efforts.
J Med Chem
; 64(4): 2291-2309, 2021 02 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33573376
11.
Plasmodium falciparum spermidine synthase inhibition results in unique perturbation-specific effects observed on transcript, protein and metabolite levels.
BMC Genomics
; 11: 235, 2010 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-20385001
12.
Acute Kidney Injury, Risk Factors, and Prognosis in Hospitalized HIV-Infected Adults in South Africa, Compared by Tenofovir Exposure.
AIDS Res Hum Retroviruses
; 33(1): 33-40, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27478997
13.
Expression of the alpha1A-adrenergic receptor in schizophrenia.
Neurosci Lett
; 401(3): 248-51, 2006 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-16600500
14.
Discovering New Transmission-Blocking Antimalarial Compounds: Challenges and Opportunities.
Trends Parasitol
; 32(9): 669-681, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27209388
15.
Association between dopamine D3 receptor gene polymorphisms and schizophrenia in an isolate population.
Schizophr Res
; 73(1): 49-54, 2005 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15567076
16.
Pharmacogenomics of psychiatric drug treatment.
Curr Opin Mol Ther
; 5(6): 642-9, 2003 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-14755891
17.
Clinical applications of pharmacogenetics in psychiatry.
Psychopharmacology (Berl)
; 162(1): 18-23, 2002 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12107612
18.
Role of pharmacogenomics in individualising treatment with SSRIs.
CNS Drugs
; 17(3): 143-51, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-12617694
19.
Genetic predictors of therapeutic response to clozapine: current status of research.
CNS Drugs
; 16(5): 317-24, 2002.
Artigo
em Inglês
| MEDLINE | ID: mdl-11994021
20.
Review of existing experimental approaches for the clinical evaluation of the benefits of plant food supplements on cardiovascular function.
Food Funct
; 4(6): 856-70, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23673390