Detalhe da pesquisa
1.
Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability.
Cell
; 186(22): 4898-4919.e25, 2023 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37827155
2.
Deregulations of miR-1 and its target Multiplexin promote dilated cardiomyopathy associated with myotonic dystrophy type 1.
EMBO Rep
; 24(4): e56616, 2023 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36852954
3.
Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy.
Genes Dev
; 31(11): 1122-1133, 2017 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28698297
4.
Intracerebral Distribution of CAG Repeat-Binding Small Molecule Visualized by Whole-Brain Imaging.
Bioconjug Chem
; 34(12): 2187-2193, 2023 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37948852
5.
CAG repeat-binding small molecule improves motor coordination impairment in a mouse model of Dentatorubral-pallidoluysian atrophy.
Neurobiol Dis
; 163: 105604, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34968706
6.
A CTG repeat-selective chemical screen identifies microtubule inhibitors as selective modulators of toxic CUG RNA levels.
Proc Natl Acad Sci U S A
; 116(42): 20991-21000, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31570586
7.
Cellular Senescence and Aging in Myotonic Dystrophy.
Int J Mol Sci
; 23(4)2022 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35216455
8.
Targeting Expanded Repeats by Small Molecules in Repeat Expansion Disorders.
Mov Disord
; 36(2): 298-305, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33284473
9.
The Dimeric Form of 1,3-Diaminoisoquinoline Derivative Rescued the Mis-splicing of Atp2a1 and Clcn1 Genes in Myotonic Dystrophy Typeâ 1 Mouse Model.
Chemistry
; 26(63): 14305-14309, 2020 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32449537
10.
Modulating RNA secondary and tertiary structures by mismatch binding ligands.
Methods
; 167: 78-91, 2019 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31078794
11.
The myotonic dystrophy health index: Japanese adaption and validity testing.
Muscle Nerve
; 59(5): 577-582, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30681157
12.
A Dimeric 2,9-Diamino-1,10-phenanthroline Derivative Improves Alternative Splicing in Myotonic Dystrophy Typeâ 1 Cell and Mouse Models.
Chemistry
; 24(68): 18115-18122, 2018 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30302858
13.
Targeting nuclear RNA for in vivo correction of myotonic dystrophy.
Nature
; 488(7409): 111-5, 2012 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22859208
14.
Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects.
Nucleic Acids Res
; 42(10): 6591-602, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24799433
15.
Detection of slipped-DNAs at the trinucleotide repeats of the myotonic dystrophy type I disease locus in patient tissues.
PLoS Genet
; 9(12): e1003866, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24367268
16.
Muscle weakness in myotonic dystrophy associated with misregulated splicing and altered gating of Ca(V)1.1 calcium channel.
Hum Mol Genet
; 21(6): 1312-24, 2012 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22140091
17.
Splicing biomarkers of disease severity in myotonic dystrophy.
Ann Neurol
; 74(6): 862-72, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23929620
18.
From dynamic combinatorial 'hit' to lead: in vitro and in vivo activity of compounds targeting the pathogenic RNAs that cause myotonic dystrophy.
Nucleic Acids Res
; 40(13): 6380-90, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22492623
19.
[Myotonia and cardiac conduction defects in myotonic dystrophy and defect in ion channels].
Rinsho Byori
; 62(3): 246-54, 2014 Mar.
Artigo
em Japonês
| MEDLINE | ID: mdl-24800500
20.
Contribution of Complement, Microangiopathy and Inflammation in Idiopathic Inflammatory Myopathies.
J Neuromuscul Dis
; 11(1): 5-16, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38143369