Detalhe da pesquisa
1.
TFEB and TFE3 control glucose homeostasis by regulating insulin gene expression.
EMBO J
; 42(21): e113928, 2023 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37712288
2.
Increased expression or activation of TRPML1 reduces hepatic storage of toxic Z alpha-1 antitrypsin.
Mol Ther
; 31(9): 2651-2661, 2023 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37394797
3.
Nutrient-sensitive transcription factors TFEB and TFE3 couple autophagy and metabolism to the peripheral clock.
EMBO J
; 38(12)2019 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31126958
4.
Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB.
PLoS Pathog
; 16(6): e1008567, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32574211
5.
Enhancement of hepatic autophagy increases ureagenesis and protects against hyperammonemia.
Proc Natl Acad Sci U S A
; 115(2): 391-396, 2018 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29279371
6.
HDAC6-dependent ciliophagy is involved in ciliary loss and cholangiocarcinoma growth in human cells and murine models.
Am J Physiol Gastrointest Liver Physiol
; 318(6): G1022-G1033, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32338033
7.
Activation of the c-Jun N-terminal kinase pathway aggravates proteotoxicity of hepatic mutant Z alpha1-antitrypsin.
Hepatology
; 65(6): 1865-1874, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28073160
8.
Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell Proteinopathy.
J Biol Chem
; 290(50): 29742-57, 2015 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26494620
10.
Loss of the batten disease protein CLN3 leads to mis-trafficking of M6PR and defective autophagic-lysosomal reformation.
Nat Commun
; 14(1): 3911, 2023 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37400440
11.
TFEB regulates murine liver cell fate during development and regeneration.
Nat Commun
; 11(1): 2461, 2020 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32424153
12.
Keeping the autophagy tempo.
Autophagy
; 15(10): 1854-1856, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31318631
13.
Fasting Imparts a Switch to Alternative Daily Pathways in Liver and Muscle.
Cell Rep
; 25(12): 3299-3314.e6, 2018 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30566858
14.
TFE3 regulates whole-body energy metabolism in cooperation with TFEB.
EMBO Mol Med
; 9(5): 605-621, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28283651
15.
Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth.
Science
; 356(6343): 1188-1192, 2017 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28619945
16.
TFEB and TFE3 cooperate in the regulation of the innate immune response in activated macrophages.
Autophagy
; 12(8): 1240-58, 2016 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27171064
17.
Correction of hyperbilirubinemia in gunn rats by surgical delivery of low doses of helper-dependent adenoviral vectors.
Hum Gene Ther Methods
; 25(3): 181-6, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24593043
18.
Wilson disease protein ATP7B utilizes lysosomal exocytosis to maintain copper homeostasis.
Dev Cell
; 29(6): 686-700, 2014 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24909901
19.
Autophagy master regulator TFEB induces clearance of toxic SERPINA1/α-1-antitrypsin polymers.
Autophagy
; 9(7): 1094-6, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23584152
20.
Improved efficacy and reduced toxicity by ultrasound-guided intrahepatic injections of helper-dependent adenoviral vector in Gunn rats.
Hum Gene Ther Methods
; 24(5): 321-7, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23947957