Detalhe da pesquisa
1.
Discovery of a novel highly potent broad-spectrum heterocyclic chemical series of arenavirus cell entry inhibitors.
Bioorg Med Chem Lett
; 41: 127983, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33965007
2.
SAR studies of 4-acyl-1,6-dialkylpiperazin-2-one arenavirus cell entry inhibitors.
Bioorg Med Chem Lett
; 29(22): 126620, 2019 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31537423
3.
Design and synthesis of a novel pyrrolidinyl pyrido pyrimidinone derivative as a potent inhibitor of PI3Kα and mTOR.
Bioorg Med Chem Lett
; 22(15): 5098-103, 2012 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22749419
4.
Azaindole N-methyl hydroxamic acids as HIV-1 integrase inhibitors-II. The impact of physicochemical properties on ADME and PK.
Bioorg Med Chem Lett
; 20(24): 7429-34, 2010 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21036042
5.
Discovery of Selective Small Molecule Degraders of BRAF-V600E.
J Med Chem
; 63(8): 4069-4080, 2020 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32223235
6.
Discovery of First-In-Class Potent and Selective Tropomyosin Receptor Kinase Degraders.
J Med Chem
; 63(23): 14562-14575, 2020 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33058680
7.
Discovery of Adamantane Carboxamides as Ebola Virus Cell Entry and Glycoprotein Inhibitors.
ACS Med Chem Lett
; 11(6): 1160-1167, 2020 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32550996
8.
(3aS,7aS)-5-[(S)-3,3,3-Trifluoro-2-meth-oxy-2-phenyl-propano-yl]-2,3,4,5,6,7-hexa-hydro-1H-pyrrolo[3,4-c]pyridin-3(2H)-one monohydrate.
Acta Crystallogr Sect E Struct Rep Online
; 66(Pt 1): o175-6, 2009 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21580061
9.
New beta-alanine derivatives are orally available glucagon receptor antagonists.
J Med Chem
; 50(1): 113-28, 2007 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-17201415
10.
Optimization of alkylidene hydrazide based human glucagon receptor antagonists. Discovery of the highly potent and orally available 3-cyano-4-hydroxybenzoic acid [1-(2,3,5,6-tetramethylbenzyl)-1H-indol-4-ylmethylene]hydrazide.
J Med Chem
; 45(26): 5755-75, 2002 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-12477359
11.
Design and synthesis of novel N-hydroxy-dihydronaphthyridinones as potent and orally bioavailable HIV-1 integrase inhibitors.
J Med Chem
; 54(9): 3393-417, 2011 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21446745
12.
Azaindole hydroxamic acids are potent HIV-1 integrase inhibitors.
J Med Chem
; 52(22): 7211-9, 2009 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-19873974
13.
Human glucagon receptor antagonists based on alkylidene hydrazides.
Bioorg Med Chem Lett
; 12(4): 663-6, 2002 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-11844695