Detalhe da pesquisa
1.
Recommendations for empowering early career researchers to improve research culture and practice.
PLoS Biol
; 20(7): e3001680, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35797414
2.
Probing SARS-CoV-2-positive plasma to identify potential factors correlating with mild COVID-19 in Ghana, West Africa.
BMC Med
; 20(1): 370, 2022 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36184636
3.
Progressive emergence of an S153F plus R263K combination of integrase mutations in the proviral DNA of one individual successfully treated with dolutegravir.
J Antimicrob Chemother
; 76(3): 639-647, 2021 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33184634
4.
Biochemical characterization of TyrA enzymes from Ignicoccus hospitalis and Haemophilus influenzae: A comparative study of the bifunctional and monofunctional dehydrogenase forms.
Biochim Biophys Acta Proteins Proteom
; 1865(3): 312-320, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-28025081
5.
Identification of a Pyridoxine-Derived Small-Molecule Inhibitor Targeting Dengue Virus RNA-Dependent RNA Polymerase.
Antimicrob Agents Chemother
; 60(1): 600-8, 2016 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26574011
6.
Characterization of the Drug Resistance Profiles of Integrase Strand Transfer Inhibitors in Simian Immunodeficiency Virus SIVmac239.
J Virol
; 89(23): 12002-13, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26378179
7.
Differential effects of the G118R, H51Y, and E138K resistance substitutions in different subtypes of HIV integrase.
J Virol
; 89(6): 3163-75, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25552724
8.
Subtype-specific analysis of the K65R substitution in HIV-1 that confers hypersusceptibility to a novel nucleotide-competing reverse transcriptase inhibitor.
Antimicrob Agents Chemother
; 59(6): 3189-96, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25779585
9.
Dolutegravir maintains a durable effect against HIV replication in tissue culture even after drug washout.
J Antimicrob Chemother
; 70(10): 2810-5, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26142476
10.
Evolution of a novel pathway leading to dolutegravir resistance in a patient harbouring N155H and multiclass drug resistance.
J Antimicrob Chemother
; 70(2): 405-11, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25281399
11.
Effect of HIV-1 integrase resistance mutations when introduced into SIVmac239 on susceptibility to integrase strand transfer inhibitors.
J Virol
; 88(17): 9683-92, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24920794
12.
A resveratrol analog termed 3,3',4,4',5,5'-hexahydroxy-trans-stilbene is a potent HIV-1 inhibitor.
J Med Virol
; 87(12): 2054-60, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25989218
13.
The M50I polymorphic substitution in association with the R263K mutation in HIV-1 subtype B integrase increases drug resistance but does not restore viral replicative fitness.
Retrovirology
; 11: 7, 2014 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24433497
14.
HIV-1 group O integrase displays lower enzymatic efficiency and higher susceptibility to raltegravir than HIV-1 group M subtype B integrase.
Antimicrob Agents Chemother
; 58(12): 7141-50, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25224008
15.
Addition of E138K to R263K in HIV integrase increases resistance to dolutegravir, but fails to restore activity of the HIV integrase enzyme and viral replication capacity.
J Antimicrob Chemother
; 69(10): 2733-40, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24917583
16.
Upper Airway Epithelial Tissue Transcriptome Analysis Reveals Immune Signatures Associated with COVID-19 Severity in Ghanaians.
J Immunol Res
; 2024: 6668017, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38375062
17.
Development and utility of a SARS-CoV-2 pseudovirus assay for compound screening and antibody neutralization assays.
Heliyon
; 10(10): e31392, 2024 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38826759
18.
Knowledge, attitude and perception towards COVID-19 among representative educated sub-Saharan Africans: A cross-sectional study during the exponential phase of the pandemic.
PLoS One
; 19(2): e0281342, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38300957
19.
Automethylation of protein arginine methyltransferase 6 (PRMT6) regulates its stability and its anti-HIV-1 activity.
Retrovirology
; 10: 73, 2013 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-23866860
20.
Viral fitness cost prevents HIV-1 from evading dolutegravir drug pressure.
Retrovirology
; 10: 22, 2013 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23432922