Detalhe da pesquisa
1.
Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry.
J Am Chem Soc
; 144(12): 5284-5294, 2022 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35293206
2.
The Human and Mouse Islet Peptidome: Effects of Obesity and Type 2 Diabetes, and Assessment of Intraislet Production of Glucagon-like Peptide-1.
J Proteome Res
; 20(9): 4507-4517, 2021 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34423991
3.
Discordance between GLP-1R gene and protein expression in mouse pancreatic islet cells.
J Biol Chem
; 295(33): 11529-11541, 2020 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32554468
4.
Interconversion of Unexpected Thiol States Affects the Stability, Structure, and Dynamics of Antibody Engineered for Site-Specific Conjugation.
Bioconjug Chem
; 32(8): 1834-1844, 2021 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34369158
5.
Acute health effects from exposure to indoor ultrafine particles-A randomized controlled crossover study among young mild asthmatics.
Indoor Air
; 31(6): 1993-2007, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34235780
6.
A Platform for Site-Specific DNA-Antibody Bioconjugation by Using Benzoylacrylic-Labelled Oligonucleotides.
Angew Chem Int Ed Engl
; 60(49): 25905-25913, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34555238
7.
Dichloro Butenediamides as Irreversible Site-Selective Protein Conjugation Reagent.
Angew Chem Int Ed Engl
; 60(44): 23750-23755, 2021 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34472678
8.
Improved Physical Stability of an Antibody-Drug Conjugate Using Host-Guest Chemistry.
Bioconjug Chem
; 31(1): 123-129, 2020 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31794200
9.
Development and characterisation of a novel glucagon like peptide-1 receptor antibody.
Diabetologia
; 61(3): 711-721, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29119245
10.
Use of CRISPR/Cas9-engineered INS-1 pancreatic ß cells to define the pharmacology of dual GIPR/GLP-1R agonists.
Biochem J
; 473(18): 2881-91, 2016 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27422784
11.
High Affinity Recognition of a Selected Amino Acid Epitope within a Protein by Cucurbit[8]uril Complexation.
Angew Chem Int Ed Engl
; 55(45): 14000-14004, 2016 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27735110
12.
Structural and pharmacological characterization of novel potent and selective monoclonal antibody antagonists of glucose-dependent insulinotropic polypeptide receptor.
J Biol Chem
; 288(27): 19760-72, 2013 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23689510
13.
Dose-response curves for co-exposure inhalation challenges with ozone and pollen allergen.
Eur Respir J
; 54(2)2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31048347
14.
The effect of air quality on sleep and cognitive performance in school children aged 10-12 years: a double-blinded, placebo-controlled, crossover trial.
Int J Occup Med Environ Health
; 36(2): 177-191, 2023 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36861764
15.
Mechanistic insights into the rational design of masked antibodies.
MAbs
; 14(1): 2095701, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35799328
16.
Controlled masking and targeted release of redox-cycling ortho-quinones via a C-C bond-cleaving 1,6-elimination.
Nat Chem
; 14(7): 754-765, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35764792
17.
The Effect of Seasonal Priming on Specific Inhalation Challenges With Birch and Grass Allergen Among Persons With Allergic Rhinitis.
Front Allergy
; 2: 737799, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35387055
18.
Gut Hormone GIP Induces Inflammation and Insulin Resistance in the Hypothalamus.
Endocrinology
; 161(9)2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32603429
19.
An RCT of acute health effects in COPD-patients after passive vape exposure from e-cigarettes.
Eur Clin Respir J
; 8(1): 1861580, 2020 Dec 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33456728
20.
Pharmacological antagonism of the incretin system protects against diet-induced obesity.
Mol Metab
; 32: 44-55, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32029229