Detalhe da pesquisa
1.
Efficacy of multivalent adenovirus-based vaccine against simian immunodeficiency virus challenge.
J Virol
; 84(6): 2996-3003, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20042509
2.
Design and synthesis of substituted 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamides, novel HIV-1 integrase inhibitors.
Bioorg Med Chem Lett
; 18(2): 721-5, 2008 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18078751
3.
10-Hydroxy-7,8-dihydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-1,9(2H,6H)-diones: potent, orally bioavailable HIV-1 integrase strand-transfer inhibitors with activity against integrase mutants.
Bioorg Med Chem Lett
; 18(16): 4581-3, 2008 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18657970
4.
8-Hydroxy-3,4-dihydropyrrolo[1,2-a]pyrazine-1(2H)-one HIV-1 integrase inhibitors.
Bioorg Med Chem Lett
; 17(23): 6511-5, 2007 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17931865
5.
Efficacy of indinavir-ritonavir-based regimens in HIV-1-infected patients with prior protease inhibitor failures.
AIDS
; 17(13): 1933-9, 2003 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-12960826
6.
3'-Tetrahydrofuranylglycine as a Novel, Unnatural Amino Acid Surrogate for Asparagine in the Design of Inhibitors of the HIV Protease.
J Am Chem Soc
; 115(2): 801-803, 1993 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30364398
7.
Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors.
J Med Chem
; 46(10): 1831-44, 2003 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-12723947
8.
Design and synthesis of 8-hydroxy-[1,6]naphthyridines as novel inhibitors of HIV-1 integrase in vitro and in infected cells.
J Med Chem
; 46(4): 453-6, 2003 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-12570367
9.
CCR5 antagonists: 3-(pyrrolidin-1-yl)propionic acid analogues with potent anti-HIV activity.
Org Lett
; 5(14): 2473-5, 2003 Jul 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-12841758
10.
The effect of early versus delayed challenge after vaccination in controlling SHIV 89.6P infection.
Virology
; 381(1): 75-80, 2008 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-18793788
11.
Synthesis of novel HIV protease inhibitors (PI) with activity against PI-resistant virus.
Bioorg Med Chem Lett
; 17(19): 5432-6, 2007 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17692518
12.
Early depletion of proliferating B cells of germinal center in rapidly progressive simian immunodeficiency virus infection.
Virology
; 361(2): 455-64, 2007 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-17223151
13.
Dihydroxypyridopyrazine-1,6-dione HIV-1 integrase inhibitors.
Bioorg Med Chem Lett
; 17(20): 5595-9, 2007 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17822898
14.
Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors possessing augmented P2' side chains.
Bioorg Med Chem Lett
; 16(4): 859-63, 2006 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16298527
15.
A series of 5-aminosubstituted 4-fluorobenzyl-8-hydroxy-[1,6]naphthyridine-7-carboxamide HIV-1 integrase inhibitors.
Bioorg Med Chem Lett
; 16(11): 2900-4, 2006 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16554152
16.
Covalent stabilization of coiled coils of the HIV gp41 N region yields extremely potent and broad inhibitors of viral infection.
Proc Natl Acad Sci U S A
; 102(36): 12903-8, 2005 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-16129831
17.
Orally bioavailable highly potent HIV protease inhibitors against PI-resistant virus.
Bioorg Med Chem Lett
; 15(23): 5311-4, 2005 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16203148
18.
Synthesis and evaluation of CCR5 antagonists containing modified 4-piperidinyl-2-phenyl-1-(phenylsulfonylamino)-butane.
Bioorg Med Chem Lett
; 15(4): 977-82, 2005 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15686896
19.
Cytotoxic T-lymphocyte escape does not always explain the transient control of simian immunodeficiency virus SIVmac239 viremia in adenovirus-boosted and DNA-primed Mamu-A*01-positive rhesus macaques.
J Virol
; 79(24): 15556-66, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16306626
20.
Potent 1,3,4-trisubstituted pyrrolidine CCR5 receptor antagonists: effects of fused heterocycles on antiviral activity and pharmacokinetic properties.
Bioorg Med Chem Lett
; 15(8): 2129-34, 2005 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15808483