Detalhe da pesquisa
1.
FDA and industry collaboration: Identifying opportunities to further reduce reliance on nonhuman primates for nonclinical safety evaluations.
Regul Toxicol Pharmacol
; 138: 105327, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36586472
2.
Nonclinical safety assessment of engineered T cell therapies.
Regul Toxicol Pharmacol
; 127: 105064, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34656748
3.
The T-cell-dependent antibody response assay in nonclinical studies of pharmaceuticals and chemicals: study design, data analysis, interpretation.
Regul Toxicol Pharmacol
; 69(1): 7-21, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24566336
4.
Current nonclinical approaches for immune assessments of immuno-oncology biotherapeutics.
Drug Discov Today
; 28(2): 103440, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36375739
5.
Comprehensive BCMA Expression Profiling in Adult Normal Human Brain Suggests a Low Risk of On-target Neurotoxicity in BCMA-targeting Multiple Myeloma Therapy.
J Histochem Cytochem
; 70(4): 273-287, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35193424
6.
Summary of a workshop on preclinical and translational safety assessment of CD3 bispecifics.
J Immunotoxicol
; 17(1): 67-85, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32100588
7.
Immunomodulatory effects of dietary potassium perfluorooctane sulfonate (PFOS) exposure in adult Sprague-Dawley rats.
J Toxicol Environ Health A
; 71(23): 1516-25, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18923994
8.
Animal models of idiosyncratic drug reactions.
Chem Biol Interact
; 150(1): 53-70, 2004 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15522261
9.
Developmental immunotoxicity (DIT) testing of pharmaceuticals: current practices, state of the science, knowledge gaps, and recommendations.
J Immunotoxicol
; 9(2): 210-30, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22428536
10.
Monoclonal antibody therapeutics: history and future.
Curr Opin Pharmacol
; 12(5): 615-22, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22920732
11.
Study of the sequence of events involved in nevirapine-induced skin rash in Brown Norway rats.
Chem Res Toxicol
; 19(9): 1205-14, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16978025
12.
Evidence of an immune-mediated mechanism for an idiosyncratic nevirapine-induced reaction in the female Brown Norway rat.
Chem Res Toxicol
; 18(12): 1799-813, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16359170
13.
Investigation of the involvement of macrophages and T cells in D-penicillamine-induced autoimmunity in the Brown Norway rat.
J Immunotoxicol
; 1(2): 79-93, 2004 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18958641
14.
Characterization of a potential animal model of an idiosyncratic drug reaction: nevirapine-induced skin rash in the rat.
Chem Res Toxicol
; 16(9): 1078-89, 2003 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12971795