Detalhe da pesquisa
1.
Azologization and repurposing of a hetero-stilbene-based kinase inhibitor: towards the design of photoswitchable sirtuin inhibitors.
Beilstein J Org Chem
; 15: 2170-2183, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31598174
2.
Identification of Bichalcones as Sirtuin Inhibitors by Virtual Screening and In Vitro Testing.
Molecules
; 23(2)2018 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29443909
3.
Three-Component Aminoalkylations Yielding Dihydronaphthoxazine-Based Sirtuin Inhibitors: Scaffold Modification and Exploration of Space for Polar Side-Chains.
Arch Pharm (Weinheim)
; 350(7)2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28547816
4.
Sirtuin 1 Inhibiting Thiocyanates (S1th)-A New Class of Isotype Selective Inhibitors of NAD+ Dependent Lysine Deacetylases.
Front Oncol
; 10: 657, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32426286
5.
New chemical tools for probing activity and inhibition of the NAD+-dependent lysine deacylase sirtuin 2.
Philos Trans R Soc Lond B Biol Sci
; 373(1748)2018 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29685963
6.
Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals).
J Med Chem
; 61(2): 482-491, 2018 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28379698