Detalhe da pesquisa
1.
Systematic Modification of the Substitution Pattern of the 7-Hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide Scaffold Enabled the Discovery of New Ligands with High Affinity and Selectivity for the Cannabinoid Type 2 Receptor.
Molecules
; 28(13)2023 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37446625
2.
Ruthenium-catalyzed synthesis of 5-amino-1,2,3-triazole-4-carboxylates for triazole-based scaffolds: beyond the dimroth rearrangement.
J Org Chem
; 80(5): 2562-72, 2015 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25654488
3.
In Memory of Maurizio Botta: His Contribution to the Development of Computer-Aided Drug Design.
J Chem Inf Model
; 59(12): 4961-4967, 2019 12 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31804073
4.
Stereoretentive chlorination of cyclic alcohols catalyzed by titanium(IV) tetrachloride: evidence for a front side attack mechanism.
J Org Chem
; 78(5): 2118-27, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23298402
5.
Unconventional plasticity of HIV-1 reverse transcriptase: how inhibitors could open a connection "gate" between allosteric and catalytic sites.
J Chem Inf Model
; 53(12): 3117-22, 2013 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24256065
6.
Stereochemical preference of 2'-deoxycytidine for chiral bis(diamido)-bridged basket resorcin[4]arenes.
Chirality
; 25(12): 840-51, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24038320
7.
Characterization of COR627 and COR628, two novel positive allosteric modulators of the GABA(B) receptor.
J Pharmacol Exp Ther
; 340(3): 529-38, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22129594
8.
N-linked peptidoresorc[4]arene-based receptors as noncompetitive inhibitors for α-chymotrypsin.
J Org Chem
; 76(11): 4396-407, 2011 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-21534559
9.
Microwave-assisted intramolecular Huisgen cycloaddition of azido alkynes derived from alpha-amino acids.
J Org Chem
; 74(3): 1314-21, 2009 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-19138079
10.
A dynamic target-based pharmacophoric model mapping the CD4 binding site on HIV-1 gp120 to identify new inhibitors of gp120-CD4 protein-protein interactions.
Bioorg Med Chem Lett
; 19(21): 6087-91, 2009 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19783140
11.
Interactions of vinca alkaloid subunits with chiral amido[4]resorcinarenes: a dynamic, kinetic, and spectroscopic study.
Org Biomol Chem
; 7(9): 1798-806, 2009 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-19590774
12.
Pharmacophore modeling for qualitative prediction of antiestrogenic activity.
J Chem Inf Model
; 49(11): 2489-97, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19877675
13.
Tetrahydrofuran acetogenins from Laurencia glandulifera.
J Nat Prod
; 72(2): 190-3, 2009 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19138151
14.
Structure-activity relationship studies of a new series of imidazo[2,1-f]purinones as potent and selective A(3) adenosine receptor antagonists.
Bioorg Med Chem
; 16(24): 10281-94, 2008 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19006671
15.
Dihydro-alkylthio-benzyl-oxopyrimidines as inhibitors of reverse transcriptase: synthesis and rationalization of the biological data on both wild-type enzyme and relevant clinical mutants.
J Med Chem
; 50(26): 6580-95, 2007 Dec 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-18052319
16.
Pharmacophore based receptor modeling: the case of adenosine A3 receptor antagonists. An approach to the optimization of protein models.
J Med Chem
; 49(14): 4085-97, 2006 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-16821770
17.
Molecular Recognition of Natural Products by Resorc[4]arene Receptors.
Curr Pharm Des
; 22(12): 1715-29, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26654589
18.
Antifungal agents. 11. N-substituted derivatives of 1-[(aryl)(4-aryl-1H-pyrrol-3-yl)methyl]-1H-imidazole: synthesis, anti-Candida activity, and QSAR studies.
J Med Chem
; 48(16): 5140-53, 2005 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-16078834
19.
AMBER force field implementation of the boronate function to simulate the inhibition of beta-lactamases by alkyl and aryl boronic acids.
Eur J Med Chem
; 40(11): 1134-42, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16153747
20.
Discovery and cardioprotective effects of the first non-Peptide agonists of the G protein-coupled prokineticin receptor-1.
PLoS One
; 10(4): e0121027, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25831128