Detalhe da pesquisa
1.
NPP-669, a prodrug of cidofovir, is highly efficacious against human adenovirus infection in the permissive Syrian hamster model.
Antimicrob Agents Chemother
; : e0048924, 2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38775484
2.
Targeting Lin28 axis enhances glypican-3-CAR T cell efficacy against hepatic tumor initiating cell population.
Mol Ther
; 31(3): 715-728, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36609146
3.
NPP-669, a Novel Broad-Spectrum Antiviral Therapeutic with Excellent Cellular Uptake, Antiviral Potency, Oral Bioavailability, Preclinical Efficacy, and a Promising Safety Margin.
Mol Pharm
; 20(1): 370-382, 2023 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36484496
4.
Identification of Ebselen derivatives as novel SARS-CoV-2 main protease inhibitors: Design, synthesis, biological evaluation, and structure-activity relationships exploration.
Bioorg Med Chem
; 96: 117531, 2023 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37972434
5.
Filociclovir Is a Potent In Vitro and In Vivo Inhibitor of Human Adenoviruses.
Antimicrob Agents Chemother
; 64(11)2020 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32816736
6.
Pathology in Permissive Syrian Hamsters after Infection with Species C Human Adenovirus (HAdV-C) Is the Result of Virus Replication: HAdV-C6 Replicates More and Causes More Pathology than HAdV-C5.
J Virol
; 91(10)2017 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28250128
7.
Correction: STAT2 Knockout Syrian Hamsters Support Enhanced Replication and Pathogenicity of Human Adenovirus, Revealing an Important Role of Type I Interferon Response in Viral Control.
PLoS Pathog
; 12(1): e1005392, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26745633
8.
Biographical Feature: William S. M. Wold, Ph.D., 1944-2021.
J Virol
; 95(22): e0118421, 2021 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34549981
9.
STAT2 Knockout Syrian Hamsters Support Enhanced Replication and Pathogenicity of Human Adenovirus, Revealing an Important Role of Type I Interferon Response in Viral Control.
PLoS Pathog
; 11(8): e1005084, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26291525
10.
[Long term results after invasive treatment of critical limb ischemia]. / A krónikus kritikus végtagischaemia invazív kezelésének hosszú távú eredményei.
Orv Hetil
; 158(11): 418-425, 2017 Mar.
Artigo
em Húngaro
| MEDLINE | ID: mdl-28287292
11.
Investigation of hydrophobically derivatized hyperbranched polyglycerol with PEGylated shell as a nanocarrier for systemic delivery of chemotherapeutics.
Nanomedicine
; 11(7): 1785-95, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25981338
12.
Ganciclovir inhibits human adenovirus replication and pathogenicity in permissive immunosuppressed Syrian hamsters.
Antimicrob Agents Chemother
; 58(12): 7171-81, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25224011
13.
Transpedal access after failed anterograde recanalization of complex below-the-knee and femoropoliteal occlusions in critical limb ischemia.
Catheter Cardiovasc Interv
; 83(6): 997-1007, 2014 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24142739
14.
Oral USC-093, a novel homoserinamide analogue of the tyrosinamide (S)-HPMPA prodrug USC-087 has decreased nephrotoxicity while maintaining antiviral efficacy against human adenovirus infection of Syrian hamsters.
Antiviral Res
; 222: 105799, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38190973
15.
Hydrogel Delivery Device for the In Vitro and In Vivo Sustained Release of Active rhGALNS Enzyme.
Pharmaceuticals (Basel)
; 16(7)2023 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37513843
16.
Identification of novel 1,2,3-triazole isatin derivatives as potent SARS-CoV-2 3CLpro inhibitors via click-chemistry-based rapid screening.
RSC Med Chem
; 14(10): 2068-2078, 2023 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37859715
17.
Design, Synthesis, and Biological Evaluation of Trisubstituted Piperazine Derivatives as Noncovalent Severe Acute Respiratory Syndrome Coronavirus 2 Main Protease Inhibitors with Improved Antiviral Activity and Favorable Druggability.
J Med Chem
; 66(23): 16426-16440, 2023 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37992202
18.
Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition.
BMC Cancer
; 12: 293, 2012 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22804960
19.
Filociclovir is a potent inhibitor of human adenovirus F41.
Antiviral Res
; 208: 105431, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36209985
20.
Discovery and Crystallographic Studies of Nonpeptidic Piperazine Derivatives as Covalent SARS-CoV-2 Main Protease Inhibitors.
J Med Chem
; 65(24): 16902-16917, 2022 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36475694