Detalhe da pesquisa
1.
TSPYL5 Depletion Induces Specific Death of ALT Cells through USP7-Dependent Proteasomal Degradation of POT1.
Mol Cell
; 75(3): 469-482.e6, 2019 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31278054
2.
PAR-TERRA is the main contributor to telomeric repeat-containing RNA transcripts in normal and cancer mouse cells.
RNA
; 27(1): 106-121, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33127860
3.
ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2.
Nucleic Acids Res
; 47(4): 1896-1907, 2019 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30629181
4.
No effect of the endurance training status on senescence despite reduced inflammation in skeletal muscle of older individuals.
Am J Physiol Endocrinol Metab
; 319(2): E447-E454, 2020 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32691630
5.
Expression of progerin in aging mouse brains reveals structural nuclear abnormalities without detectible significant alterations in gene expression, hippocampal stem cells or behavior.
Hum Mol Genet
; 24(5): 1305-21, 2015 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25343989
6.
Neuromelanin activates proinflammatory microglia through a caspase-8-dependent mechanism.
J Neuroinflammation
; 12: 5, 2015 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25586882
7.
Senescence-related impairment of autophagy induces toxic intraneuronal amyloid-ß accumulation in a mouse model of amyloid pathology.
Acta Neuropathol Commun
; 11(1): 82, 2023 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37198698
8.
ZNF524 directly interacts with telomeric DNA and supports telomere integrity.
Nat Commun
; 14(1): 8252, 2023 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38086788
9.
At a glance: the largest Niemann-Pick type C1 cohort with 602 patients diagnosed over 15 years.
Eur J Hum Genet
; 31(10): 1108-1116, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37433892
10.
Mitochondrial oxidative stress induced by Ca2+ and monoamines: different behaviour of liver and brain mitochondria in undergoing permeability transition.
Amino Acids
; 42(2-3): 751-9, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21805134
11.
Polyamine catabolism: target for antiproliferative therapies in animals and stress tolerance strategies in plants.
Amino Acids
; 42(2-3): 411-26, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21874532
12.
An integrated multiomic approach as an excellent tool for the diagnosis of metabolic diseases: our first 3720 patients.
Eur J Hum Genet
; 30(9): 1029-1035, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35614200
13.
The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1.
Nat Commun
; 12(1): 2668, 2021 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33976151
14.
Cytotoxicity of spermine oxidation products to multidrug resistant melanoma M14 ADR2 cells: sensitization by the MDL 72527 lysosomotropic compound.
Int J Oncol
; 35(3): 485-98, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19639169
15.
Accumulation of Progerin Affects the Symmetry of Cell Division and Is Associated with Impaired Wnt Signaling and the Mislocalization of Nuclear Envelope Proteins.
J Invest Dermatol
; 139(11): 2272-2280.e12, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31128203
16.
Highly Aggressive Metastatic Melanoma Cells Unable to Maintain Telomere Length.
Cell Rep
; 19(12): 2529-2543, 2017 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28636941
17.
Rare progerin-expressing preadipocytes and adipocytes contribute to tissue depletion over time.
Sci Rep
; 7(1): 4405, 2017 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28667315
18.
Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation.
Cell Rep
; 10(9): 1626-1638, 2015 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25753426
19.
Low levels of the reverse transactivator fail to induce target transgene expression in vascular smooth muscle cells.
PLoS One
; 9(8): e104098, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25090270
20.
Embryonic expression of the common progeroid lamin A splice mutation arrests postnatal skin development.
Aging Cell
; 13(2): 292-302, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24305605