Detalhe da pesquisa
1.
Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis.
J Am Chem Soc
; 142(9): 4445-4455, 2020 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32064871
2.
Biased Complement Diversity Selection for Effective Exploration of Chemical Space in Hit-Finding Campaigns.
J Chem Inf Model
; 59(5): 1709-1714, 2019 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30943027
3.
Molecular Basis of mRNA Cap Recognition by Influenza B Polymerase PB2 Subunit.
J Biol Chem
; 291(1): 363-70, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26559973
4.
Structural and biophysical comparisons of the pomalidomide- and CC-220-induced interactions of SALL4 with cereblon.
Sci Rep
; 13(1): 22088, 2023 12 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38086859
5.
Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections.
Science
; 380(6652): 1349-1356, 2023 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37384702
6.
Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy.
Cell Chem Biol
; 30(3): 235-247.e12, 2023 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36863346
7.
Biosensor-based small molecule fragment screening with biolayer interferometry.
J Comput Aided Mol Des
; 25(7): 669-76, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21660516
8.
Biochemical Characterization of Respiratory Syncytial Virus RNA-Dependent RNA Polymerase Complex.
ACS Infect Dis
; 6(10): 2800-2811, 2020 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32886480
9.
A polyomavirus peptide binds to the capsid VP1 pore and has potent antiviral activity against BK and JC polyomaviruses.
Elife
; 92020 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31960795
10.
Structural and Biological Basis of Small Molecule Inhibition of Escherichia coli LpxD Acyltransferase Essential for Lipopolysaccharide Biosynthesis.
ACS Infect Dis
; 6(6): 1480-1489, 2020 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31402665
11.
Inhibition of IRF5 cellular activity with cell-penetrating peptides that target homodimerization.
Sci Adv
; 6(20): eaay1057, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32440537
12.
Structural basis for therapeutic inhibition of influenza A polymerase PB2 subunit.
Sci Rep
; 7(1): 9385, 2017 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28839261
13.
Inhibition of prenylated KRAS in a lipid environment.
PLoS One
; 12(4): e0174706, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28384226
14.
A novel antiangiogenesis therapy using an integrin antagonist or anti-Flk-1 antibody coated 90Y-labeled nanoparticles.
Int J Radiat Oncol Biol Phys
; 58(4): 1215-27, 2004 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15001266
15.
Deconstruction of a nutlin: dissecting the binding determinants of a potent protein-protein interaction inhibitor.
ACS Med Chem Lett
; 4(7): 660-5, 2013 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900726
16.
Metal impurities cause false positives in high-throughput screening campaigns.
ACS Med Chem Lett
; 4(2): 197-200, 2013 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900642
17.
Label-free detection of biomolecular interactions using BioLayer interferometry for kinetic characterization.
Comb Chem High Throughput Screen
; 12(8): 791-800, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19758119
18.
Enhancement of the efficacy of an antagonist of an extracellular receptor by attachment to the surface of a biocompatible carrier.
Pharm Res
; 21(10): 1880-5, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15553236