Detalhe da pesquisa
1.
Differentiation of subnucleus-sized oligomers and nucleation-competent assemblies of the Aß peptide.
Biophys J
; 122(2): 269-278, 2023 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36529991
2.
Met/Val129 polymorphism of the full-length human prion protein dictates distinct pathways of amyloid formation.
J Biol Chem
; 298(10): 102430, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36037966
3.
Atomic Resolution Insights into pH Shift Induced Deprotonation Events in LS-Shaped Aß(1-42) Amyloid Fibrils.
J Am Chem Soc
; 145(4): 2161-2169, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36653015
4.
A So-Far Overlooked Secondary Conformation State in the Binding Mode of SARS-CoV-2 Spike Protein to Human ACE2 and Its Conversion Rate Are Crucial for Estimating Infectivity Efficacy of the Underlying Virus Variant.
J Virol
; 96(13): e0068522, 2022 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35674432
5.
Residue alterations within a conserved hydrophobic pocket influence light, oxygen, voltage photoreceptor dark recovery.
Photochem Photobiol Sci
; 22(4): 713-727, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36480084
6.
Amyloid-type Protein Aggregation and Prion-like Properties of Amyloids.
Chem Rev
; 121(13): 8285-8307, 2021 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34137605
7.
An essential role of the autophagy activating kinase ULK1 in snRNP biogenesis.
Nucleic Acids Res
; 49(11): 6437-6455, 2021 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34096600
8.
Disrupted-in-schizophrenia 1 protein aggregates in cerebrospinal fluid are elevated in patients with first-episode psychosis.
Psychiatry Clin Neurosci
; 77(12): 665-671, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37668563
9.
Stabilization of Monomeric Tau Protein by All D-Enantiomeric Peptide Ligands as Therapeutic Strategy for Alzheimer's Disease and Other Tauopathies.
Int J Mol Sci
; 24(3)2023 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36768484
10.
Structural details of amyloid ß oligomers in complex with human prion protein as revealed by solid-state MAS NMR spectroscopy.
J Biol Chem
; 296: 100499, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33667547
11.
Tryptophan (W) at position 37 of murine IL-12/IL-23 p40 is mandatory for binding to IL-12Rß1 and subsequent signal transduction.
J Biol Chem
; 297(5): 101295, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34637790
12.
Structure-Based Design of Stapled Peptides That Bind GABARAP and Inhibit Autophagy.
J Am Chem Soc
; 144(32): 14687-14697, 2022 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35917476
13.
The intramolecular allostery of GRB2 governing its interaction with SOS1 is modulated by phosphotyrosine ligands.
Biochem J
; 478(14): 2793-2809, 2021 07 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34232285
14.
Smad7 in intestinal CD4+ T cells determines autoimmunity in a spontaneous model of multiple sclerosis.
Proc Natl Acad Sci U S A
; 116(51): 25860-25869, 2019 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31796589
15.
CDC42-IQGAP Interactions Scrutinized: New Insights into the Binding Properties of the GAP-Related Domain.
Int J Mol Sci
; 23(16)2022 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36012107
16.
Biophysical and Dynamic Characterization of Fine-Tuned Binding of the Human Respiratory Syncytial Virus M2-1 Core Domain to Long RNAs.
J Virol
; 94(23)2020 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32938771
17.
Structural Insights into Curli CsgA Cross-ß Fibril Architecture Inspire Repurposing of Anti-amyloid Compounds as Anti-biofilm Agents.
PLoS Pathog
; 15(8): e1007978, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31469892
18.
Reelin Amplifies Glycoprotein VI Activation and AlphaIIb Beta3 Integrin Outside-In Signaling via PLC Gamma 2 and Rho GTPases.
Arterioscler Thromb Vasc Biol
; 40(10): 2391-2403, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32787521
19.
Histamine H3 receptor antagonists with peptidomimetic (keto)piperazine structures to inhibit Aß oligomerisation.
Bioorg Med Chem
; 50: 116462, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34695709
20.
In Vitro and In Vivo Efficacies of the Linear and the Cyclic Version of an All-d-Enantiomeric Peptide Developed for the Treatment of Alzheimer's Disease.
Int J Mol Sci
; 22(12)2021 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34207233