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1.
Brief Bioinform ; 25(4)2024 May 23.
Artigo em Inglês | MEDLINE | ID: mdl-39007595

RESUMO

Biomedical research now commonly integrates diverse data types or views from the same individuals to better understand the pathobiology of complex diseases, but the challenge lies in meaningfully integrating these diverse views. Existing methods often require the same type of data from all views (cross-sectional data only or longitudinal data only) or do not consider any class outcome in the integration method, which presents limitations. To overcome these limitations, we have developed a pipeline that harnesses the power of statistical and deep learning methods to integrate cross-sectional and longitudinal data from multiple sources. In addition, it identifies key variables that contribute to the association between views and the separation between classes, providing deeper biological insights. This pipeline includes variable selection/ranking using linear and nonlinear methods, feature extraction using functional principal component analysis and Euler characteristics, and joint integration and classification using dense feed-forward networks for cross-sectional data and recurrent neural networks for longitudinal data. We applied this pipeline to cross-sectional and longitudinal multiomics data (metagenomics, transcriptomics and metabolomics) from an inflammatory bowel disease (IBD) study and identified microbial pathways, metabolites and genes that discriminate by IBD status, providing information on the etiology of IBD. We conducted simulations to compare the two feature extraction methods.


Assuntos
Aprendizado Profundo , Doenças Inflamatórias Intestinais , Humanos , Estudos Transversais , Doenças Inflamatórias Intestinais/classificação , Doenças Inflamatórias Intestinais/genética , Estudos Longitudinais , Análise Discriminante , Metabolômica/métodos , Biologia Computacional/métodos
2.
Brief Bioinform ; 23(3)2022 05 13.
Artigo em Inglês | MEDLINE | ID: mdl-35380616

RESUMO

In the last few decades, antimicrobial peptides (AMPs) have been explored as an alternative to classical antibiotics, which in turn motivated the development of machine learning models to predict antimicrobial activities in peptides. The first generation of these predictors was filled with what is now known as shallow learning-based models. These models require the computation and selection of molecular descriptors to characterize each peptide sequence and train the models. The second generation, known as deep learning-based models, which no longer requires the explicit computation and selection of those descriptors, started to be used in the prediction task of AMPs just four years ago. The superior performance claimed by deep models regarding shallow models has created a prevalent inertia to using deep learning to identify AMPs. However, methodological flaws and/or modeling biases in the building of deep models do not support such superiority. Here, we analyze the main pitfalls that led to establish biased conclusions on the leading performance of deep models. Also, we analyze whether deep models truly contribute to achieve better predictions than shallow models by performing fair studies on different state-of-the-art benchmarking datasets. The experiments reveal that deep models do not outperform shallow models in the classification of AMPs, and that both types of models codify similar chemical information since their predictions are highly similar. Thus, according to the currently available datasets, we conclude that the use of deep learning could not be the most suitable approach to develop models to identify AMPs, mainly because shallow models achieve comparable-to-superior performances and are simpler (Ockham's razor principle). Even so, we suggest the use of deep learning only when its capabilities lead to obtaining significantly better performance gains worth the additional computational cost.


Assuntos
Aprendizado Profundo , Sequência de Aminoácidos , Peptídeos Antimicrobianos , Aprendizado de Máquina , Peptídeos/química
3.
BMC Med Inform Decis Mak ; 24(1): 198, 2024 Jul 22.
Artigo em Inglês | MEDLINE | ID: mdl-39039464

RESUMO

Genes, expressed as sequences of nucleotides, are susceptible to mutations, some of which can lead to cancer. Machine learning and deep learning methods have emerged as vital tools in identifying mutations associated with cancer. Thyroid cancer ranks as the 5th most prevalent cancer in the USA, with thousands diagnosed annually. This paper presents an ensemble learning model leveraging deep learning techniques such as Long Short-Term Memory (LSTM), Gated Recurrent Units (GRUs), and Bi-directional LSTM (Bi-LSTM) to detect thyroid cancer mutations early. The model is trained on a dataset sourced from asia.ensembl.org and IntOGen.org, consisting of 633 samples with 969 mutations across 41 genes, collected from individuals of various demographics. Feature extraction encompasses techniques including Hahn moments, central moments, raw moments, and various matrix-based methods. Evaluation employs three testing methods: self-consistency test (SCT), independent set test (IST), and 10-fold cross-validation test (10-FCVT). The proposed ensemble learning model demonstrates promising performance, achieving 96% accuracy in the independent set test (IST). Statistical measures such as training accuracy, testing accuracy, recall, sensitivity, specificity, Mathew's Correlation Coefficient (MCC), loss, training accuracy, F1 Score, and Cohen's kappa are utilized for comprehensive evaluation.


Assuntos
Aprendizado Profundo , Mutação , Neoplasias da Glândula Tireoide , Humanos , Neoplasias da Glândula Tireoide/genética , Neoplasias da Glândula Tireoide/diagnóstico , Progressão da Doença
4.
Sensors (Basel) ; 24(4)2024 Feb 07.
Artigo em Inglês | MEDLINE | ID: mdl-38400254

RESUMO

Stress has emerged as a major concern in modern society, significantly impacting human health and well-being. Statistical evidence underscores the extensive social influence of stress, especially in terms of work-related stress and associated healthcare costs. This paper addresses the critical need for accurate stress detection, emphasising its far-reaching effects on health and social dynamics. Focusing on remote stress monitoring, it proposes an efficient deep learning approach for stress detection from facial videos. In contrast to the research on wearable devices, this paper proposes novel Hybrid Deep Learning (DL) networks for stress detection based on remote photoplethysmography (rPPG), employing (Long Short-Term Memory (LSTM), Gated Recurrent Units (GRU), 1D Convolutional Neural Network (1D-CNN)) models with hyperparameter optimisation and augmentation techniques to enhance performance. The proposed approach yields a substantial improvement in accuracy and efficiency in stress detection, achieving up to 95.83% accuracy with the UBFC-Phys dataset while maintaining excellent computational efficiency. The experimental results demonstrate the effectiveness of the proposed Hybrid DL models for rPPG-based-stress detection.


Assuntos
Aprendizado Profundo , Humanos , Fotopletismografia , Face , Custos de Cuidados de Saúde , Memória de Longo Prazo
5.
J Environ Manage ; 358: 120756, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38599080

RESUMO

Water quality indicators (WQIs), such as chlorophyll-a (Chl-a) and dissolved oxygen (DO), are crucial for understanding and assessing the health of aquatic ecosystems. Precise prediction of these indicators is fundamental for the efficient administration of rivers, lakes, and reservoirs. This research utilized two unique DL algorithms-namely, convolutional neural network (CNNs) and gated recurrent units (GRUs)-alongside their amalgamation, CNN-GRU, to precisely gauge the concentration of these indicators within a reservoir. Moreover, to optimize the outcomes of the developed hybrid model, we considered the impact of a decomposition technique, specifically the wavelet transform (WT). In addition to these efforts, we created two distinct machine learning (ML) algorithms-namely, random forest (RF) and support vector regression (SVR)-to demonstrate the superior performance of deep learning algorithms over individual ML ones. We initially gathered WQIs from diverse locations and varying depths within the reservoir using an AAQ-RINKO device in the study area to achieve this. It is important to highlight that, despite utilizing diverse data-driven models in water quality estimation, a significant gap persists in the existing literature regarding implementing a comprehensive hybrid algorithm. This algorithm integrates the wavelet transform, convolutional neural network (CNN), and gated recurrent unit (GRU) methodologies to estimate WQIs accurately within a spatiotemporal framework. Subsequently, the effectiveness of the models that were developed was assessed utilizing various statistical metrics, encompassing the correlation coefficient (r), root mean square error (RMSE), mean absolute error (MAE), and Nash-Sutcliffe efficiency (NSE) throughout both the training and testing phases. The findings demonstrated that the WT-CNN-GRU model exhibited better performance in comparison with the other algorithms by 13% (SVR), 13% (RF), 9% (CNN), and 8% (GRU) when R-squared and DO were considered as evaluation indices and WQIs, respectively.


Assuntos
Algoritmos , Redes Neurais de Computação , Qualidade da Água , Aprendizado de Máquina , Monitoramento Ambiental/métodos , Lagos , Clorofila A/análise , Análise de Ondaletas
6.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi ; 41(1): 26-33, 2024 Feb 25.
Artigo em Chinês | MEDLINE | ID: mdl-38403601

RESUMO

Sleep stage classification is essential for clinical disease diagnosis and sleep quality assessment. Most of the existing methods for sleep stage classification are based on single-channel or single-modal signal, and extract features using a single-branch, deep convolutional network, which not only hinders the capture of the diversity features related to sleep and increase the computational cost, but also has a certain impact on the accuracy of sleep stage classification. To solve this problem, this paper proposes an end-to-end multi-modal physiological time-frequency feature extraction network (MTFF-Net) for accurate sleep stage classification. First, multi-modal physiological signal containing electroencephalogram (EEG), electrocardiogram (ECG), electrooculogram (EOG) and electromyogram (EMG) are converted into two-dimensional time-frequency images containing time-frequency features by using short time Fourier transform (STFT). Then, the time-frequency feature extraction network combining multi-scale EEG compact convolution network (Ms-EEGNet) and bidirectional gated recurrent units (Bi-GRU) network is used to obtain multi-scale spectral features related to sleep feature waveforms and time series features related to sleep stage transition. According to the American Academy of Sleep Medicine (AASM) EEG sleep stage classification criterion, the model achieved 84.3% accuracy in the five-classification task on the third subgroup of the Institute of Systems and Robotics of the University of Coimbra Sleep Dataset (ISRUC-S3), with 83.1% macro F1 score value and 79.8% Cohen's Kappa coefficient. The experimental results show that the proposed model achieves higher classification accuracy and promotes the application of deep learning algorithms in assisting clinical decision-making.


Assuntos
Fases do Sono , Sono , Fases do Sono/fisiologia , Polissonografia/métodos , Eletroencefalografia/métodos , Algoritmos
7.
Sensors (Basel) ; 23(18)2023 Sep 16.
Artigo em Inglês | MEDLINE | ID: mdl-37765990

RESUMO

Lidar presents a promising solution for bird surveillance in airport environments. However, the low observation refresh rate of Lidar poses challenges for tracking bird targets. To address this problem, we propose a gated recurrent unit (GRU)-based interacting multiple model (IMM) approach for tracking bird targets at low sampling frequencies. The proposed method constructs various GRU-based motion models to extract different motion patterns and to give different predictions of target trajectory in place of traditional target moving models and uses an interacting multiple model mechanism to dynamically select the most suitable GRU-based motion model for trajectory prediction and tracking. In order to fuse the GRU-based motion model and IMM, the approximation state transfer matrix method is proposed to transform the prediction of GRU-based network into an explicit state transfer model, which enables the calculation of the models' probability. The simulation carried out on an open bird trajectory dataset proves that our method outperforms classical tracking methods at low refresh rates with at least 26% improvement in tracking error. The results show that the proposed method is effective for tracking small bird targets based on Lidar systems, as well as for other low-refresh-rate tracking systems.

8.
Sensors (Basel) ; 23(20)2023 Oct 13.
Artigo em Inglês | MEDLINE | ID: mdl-37896526

RESUMO

This paper introduces a new bidirectional integration approach that combines fiber sensor/free space optics (FSO) communication using an intensity and wavelength division multiplexer (IWDM) techniques-based long-distance fiber Bragg grating (FBG) sensor strain-sensing system. By implementing coarse wavelength division multiplexing (CWDM), the system achieves the simultaneous transmission of optical communication and fiber optical sensor (FOS) sensing signals, resulting in a highly capable, flexible, and cost-effective solution. The proposed FSO transmission technique addresses complex fiber cable installation concerns with topographical limitations. This bidirectional structure ensures the reliability and stability of the long-distance FBG sensor system, supported by extensive research and experimentation. A hybrid stacked gated recurrent units and long short-term memory (SGRU-LSTM) model is proposed to enhance strain measurement accuracy by predicting and measuring the central wavelength of overlapped strain-sensing FBG sensor signals. The results demonstrate the superiority of the proposed model in peak wavelength detection accuracy. The primary benefit of integrating communication and sensing is the significant reduction in construction costs by eliminating the requirement for two individual fiber optic systems, as the integration allows for a single system to fulfill both functions, resulting in more efficient and cost-effective implementation. Overall, this paper contributes to advancing long-distance FBG sensor systems by integrating fiber sensor/FSO communication and deep learning techniques, improving transmission distance, multiplexing capacity, measurement accuracy, system survivability, and cost-effectiveness.

9.
Sensors (Basel) ; 22(4)2022 Feb 10.
Artigo em Inglês | MEDLINE | ID: mdl-35214241

RESUMO

Internet of Vehicles (IoV) is an application of the Internet of Things (IoT) network that connects smart vehicles to the internet, and vehicles with each other. With the emergence of IoV technology, customers have placed great attention on smart vehicles. However, the rapid growth of IoV has also caused many security and privacy challenges that can lead to fatal accidents. To reduce smart vehicle accidents and detect malicious attacks in vehicular networks, several researchers have presented machine learning (ML)-based models for intrusion detection in IoT networks. However, a proficient and real-time faster algorithm is needed to detect malicious attacks in IoV. This article proposes a hybrid deep learning (DL) model for cyber attack detection in IoV. The proposed model is based on long short-term memory (LSTM) and gated recurrent unit (GRU). The performance of the proposed model is analyzed by using two datasets-a combined DDoS dataset that contains CIC DoS, CI-CIDS 2017, and CSE-CIC-IDS 2018, and a car-hacking dataset. The experimental results demonstrate that the proposed algorithm achieves higher attack detection accuracy of 99.5% and 99.9% for DDoS and car hacks, respectively. The other performance scores, precision, recall, and F1-score, also verify the superior performance of the proposed framework.


Assuntos
Aprendizado Profundo , Internet das Coisas , Internet , Aprendizado de Máquina , Redes Neurais de Computação
10.
Sensors (Basel) ; 22(10)2022 May 11.
Artigo em Inglês | MEDLINE | ID: mdl-35632071

RESUMO

Short-term forecasting of electric energy consumption has become a critical issue for companies selling and buying electricity because of the fluctuating and rising trend of its price. Forecasting tools based on Artificial Intelligence have proved to provide accurate and reliable prediction, especially Neural Networks, which have been widely used and have become one of the preferred ones. In this work, two of them, Long Short-Term Memories and Gated Recurrent Units, have been used along with a preprocessing algorithm, the Empirical Mode Decomposition, to make up a hybrid model to predict the following 24 hourly consumptions (a whole day ahead) of a hospital. Two different datasets have been used to forecast them: a univariate one in which only consumptions are used and a multivariate one in which other three variables (reactive consumption, temperature, and humidity) have been also used. The results achieved show that the best performances were obtained with the multivariate dataset. In this scenario, the hybrid models (neural network with preprocessing) clearly outperformed the simple ones (only the neural network). Both neural models provided similar performances in all cases. The best results (Mean Absolute Percentage Error: 3.51% and Root Mean Square Error: 55.06) were obtained with the Long Short-Term Memory with preprocessing with the multivariate dataset.


Assuntos
Inteligência Artificial , Redes Neurais de Computação , Algoritmos , Atenção à Saúde , Previsões
11.
Int J Mol Sci ; 23(19)2022 Sep 29.
Artigo em Inglês | MEDLINE | ID: mdl-36232840

RESUMO

Genes are composed of DNA and each gene has a specific sequence. Recombination or replication within the gene base ends in a permanent change in the nucleotide collection in a DNA called mutation and some mutations can lead to cancer. Breast adenocarcinoma starts in secretary cells. Breast adenocarcinoma is the most common of all cancers that occur in women. According to a survey within the United States of America, there are more than 282,000 breast adenocarcinoma patients registered each 12 months, and most of them are women. Recognition of cancer in its early stages saves many lives. A proposed framework is developed for the early detection of breast adenocarcinoma using an ensemble learning technique with multiple deep learning algorithms, specifically: Long Short-Term Memory (LSTM), Gated Recurrent Units (GRU), and Bi-directional LSTM. There are 99 types of driver genes involved in breast adenocarcinoma. This study uses a dataset of 4127 samples including men and women taken from more than 12 cohorts of cancer detection institutes. The dataset encompasses a total of 6170 mutations that occur in 99 genes. On these gene sequences, different algorithms are applied for feature extraction. Three types of testing techniques including independent set testing, self-consistency testing, and a 10-fold cross-validation test is applied to validate and test the learning approaches. Subsequently, multiple deep learning approaches such as LSTM, GRU, and bi-directional LSTM algorithms are applied. Several evaluation metrics are enumerated for the validation of results including accuracy, sensitivity, specificity, Mathew's correlation coefficient, area under the curve, training loss, precision, recall, F1 score, and Cohen's kappa while the values obtained are 99.57, 99.50, 99.63, 0.99, 1.0, 0.2027, 99.57, 99.57, 99.57, and 99.14 respectively.


Assuntos
Adenocarcinoma , Neoplasias da Mama , Aprendizado Profundo , Adenocarcinoma/diagnóstico , Adenocarcinoma/genética , Neoplasias da Mama/diagnóstico , Neoplasias da Mama/genética , Carcinógenos , Feminino , Humanos , Masculino , Mutação , Nucleotídeos
12.
BMC Bioinformatics ; 22(Suppl 3): 293, 2021 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-34074242

RESUMO

BACKGROUND: Drug repositioning, meanings finding new uses for existing drugs, which can accelerate the processing of new drugs research and development. Various computational methods have been presented to predict novel drug-disease associations for drug repositioning based on similarity measures among drugs and diseases. However, there are some known associations between drugs and diseases that previous studies not utilized. METHODS: In this work, we develop a deep gated recurrent units model to predict potential drug-disease interactions using comprehensive similarity measures and Gaussian interaction profile kernel. More specifically, the similarity measure is used to exploit discriminative feature for drugs based on their chemical fingerprints. Meanwhile, the Gaussian interactions profile kernel is employed to obtain efficient feature of diseases based on known disease-disease associations. Then, a deep gated recurrent units model is developed to predict potential drug-disease interactions. RESULTS: The performance of the proposed model is evaluated on two benchmark datasets under tenfold cross-validation. And to further verify the predictive ability, case studies for predicting new potential indications of drugs were carried out. CONCLUSION: The experimental results proved the proposed model is a useful tool for predicting new indications for drugs or new treatments for diseases, and can accelerate drug repositioning and related drug research and discovery.


Assuntos
Aprendizado Profundo , Reposicionamento de Medicamentos , Algoritmos , Biologia Computacional , Simulação por Computador
13.
Chaos Solitons Fractals ; 146: 110861, 2021 May.
Artigo em Inglês | MEDLINE | ID: mdl-33746373

RESUMO

In December 2019, first case of the COVID-19 was reported in Wuhan, Hubei province in China. Soon world health organization has declared contagious coronavirus disease (a.k.a. COVID-19) as a global pandemic in the month of March 2020. Over the span of eleven months, it has rapidly spread out all over the world with total confirmed cases of ~ 41.39 M and causing a total fatality of ~1.13 M. At present, the entire mankind is facing serious threat and it is believed that COVID-19 may have been around for quite some time. Therefore, it has become imperative to forecast the global impact of COVID-19 in the near future. The present work proposes state-of-art deep learning Recurrent Neural Networks (RNN) models to predict the country-wise cumulative confirmed cases, cumulative recovered cases and the cumulative fatalities. The Gated Recurrent Units (GRUs) and Long Short-Term Memory (LSTM) cells along with Recurrent Neural Networks (RNN) were developed to predict the future trends of the COVID-19. We have used publicly available data from John Hopkins University's COVID-19 database. In this work, we emphasize the importance of various factors such as age, preventive measures, and healthcare facilities, population density, etc. that play vital role in rapid spread of COVID-19 pandemic. Therefore, our forecasted results are very helpful for countries to better prepare themselves to control the pandemic.

14.
Chaos Solitons Fractals ; 140: 110121, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-32834633

RESUMO

The novel coronavirus (COVID-19) has significantly spread over the world and comes up with new challenges to the research community. Although governments imposing numerous containment and social distancing measures, the need for the healthcare systems has dramatically increased and the effective management of infected patients becomes a challenging problem for hospitals. Thus, accurate short-term forecasting of the number of new contaminated and recovered cases is crucial for optimizing the available resources and arresting or slowing down the progression of such diseases. Recently, deep learning models demonstrated important improvements when handling time-series data in different applications. This paper presents a comparative study of five deep learning methods to forecast the number of new cases and recovered cases. Specifically, simple Recurrent Neural Network (RNN), Long short-term memory (LSTM), Bidirectional LSTM (BiLSTM), Gated recurrent units (GRUs) and Variational AutoEncoder (VAE) algorithms have been applied for global forecasting of COVID-19 cases based on a small volume of data. This study is based on daily confirmed and recovered cases collected from six countries namely Italy, Spain, France, China, USA, and Australia. Results demonstrate the promising potential of the deep learning model in forecasting COVID-19 cases and highlight the superior performance of the VAE compared to the other algorithms.

15.
Sensors (Basel) ; 20(24)2020 Dec 17.
Artigo em Inglês | MEDLINE | ID: mdl-33348876

RESUMO

Oxford Nanopore sequencing is an important sequencing technology, which reads the nucleotide sequence by detecting the electrical current signal changes when DNA molecule is forced to pass through a biological nanopore. The research on signal simulation of nanopore sequencing is highly desirable for method developments of nanopore sequencing applications. To improve the simulation accuracy, we propose a novel signal simulation method based on Bi-directional Gated Recurrent Units (BiGRU). In this method, the signal processing model based on BiGRU is built to replace the traditional low-pass filter to post-process the ground-truth signal calculated by the input nucleotide sequence and nanopore sequencing pore model. Gaussian noise is then added to the filtered signal to generate the final simulated signal. This method can accurately model the relation between ground-truth signal and real-world sequencing signal through experimental sequencing data. The simulation results reveal that the proposed method utilizing the powerful learning ability of the neural network can generate the simulated signal that is closer to the real-world sequencing signal in the time and frequency domains than the existing simulation method.

16.
Sensors (Basel) ; 20(18)2020 Sep 04.
Artigo em Inglês | MEDLINE | ID: mdl-32899773

RESUMO

Building a human-like car-following model that can accurately simulate drivers' car-following behaviors is helpful to the development of driving assistance systems and autonomous driving. Recent studies have shown the advantages of applying reinforcement learning methods in car-following modeling. However, a problem has remained where it is difficult to manually determine the reward function. This paper proposes a novel car-following model based on generative adversarial imitation learning. The proposed model can learn the strategy from drivers' demonstrations without specifying the reward. Gated recurrent units was incorporated in the actor-critic network to enable the model to use historical information. Drivers' car-following data collected by a test vehicle equipped with a millimeter-wave radar and controller area network acquisition card was used. The participants were divided into two driving styles by K-means with time-headway and time-headway when braking used as input features. Adopting five-fold cross-validation for model evaluation, the results show that the proposed model can reproduce drivers' car-following trajectories and driving styles more accurately than the intelligent driver model and the recurrent neural network-based model, with the lowest average spacing error (19.40%) and speed validation error (5.57%), as well as the lowest Kullback-Leibler divergences of the two indicators used for driving style clustering.


Assuntos
Condução de Veículo , Automóveis , Acidentes de Trânsito , Análise por Conglomerados , Simulação por Computador , Humanos , Comportamento Imitativo
17.
BMC Bioinformatics ; 20(1): 377, 2019 Jul 06.
Artigo em Inglês | MEDLINE | ID: mdl-31277574

RESUMO

BACKGROUND: Electron transport chain is a series of protein complexes embedded in the process of cellular respiration, which is an important process to transfer electrons and other macromolecules throughout the cell. It is also the major process to extract energy via redox reactions in the case of oxidation of sugars. Many studies have determined that the electron transport protein has been implicated in a variety of human diseases, i.e. diabetes, Parkinson, Alzheimer's disease and so on. Few bioinformatics studies have been conducted to identify the electron transport proteins with high accuracy, however, their performance results require a lot of improvements. Here, we present a novel deep neural network architecture to address this problem. RESULTS: Most of the previous studies could not use the original position specific scoring matrix (PSSM) profiles to feed into neural networks, leading to a lack of information and the neural networks consequently could not achieve the best results. In this paper, we present a novel approach by using deep gated recurrent units (GRU) on full PSSMs to resolve this problem. Our approach can precisely predict the electron transporters with the cross-validation and independent test accuracy of 93.5 and 92.3%, respectively. Our approach demonstrates superior performance to all of the state-of-the-art predictors on electron transport proteins. CONCLUSIONS: Through the proposed study, we provide ET-GRU, a web server for discriminating electron transport proteins in particular and other protein functions in general. Also, our achievement could promote the use of GRU in computational biology, especially in protein function prediction.


Assuntos
Complexo de Proteínas da Cadeia de Transporte de Elétrons/química , Redes Neurais de Computação , Software , Transporte de Elétrons , Humanos , Matrizes de Pontuação de Posição Específica
18.
Sensors (Basel) ; 19(2)2019 Jan 17.
Artigo em Inglês | MEDLINE | ID: mdl-30658480

RESUMO

Every year, a significant number of people lose a body part in an accident, through sickness or in high-risk manual jobs. Several studies and research works have tried to reduce the constraints and risks in their lives through the use of technology. This work proposes a learning-based approach that performs gesture recognition using a surface electromyography-based device, the Myo Armband released by Thalmic Labs, which is a commercial device and has eight non-intrusive low-cost sensors. With 35 able-bodied subjects, and using the Myo Armband device, which is able to record data at about 200 MHz, we collected a dataset that includes six dissimilar hand gestures. We used a gated recurrent unit network to train a system that, as input, takes raw signals extracted from the surface electromyography sensors. The proposed approach obtained a 99.90% training accuracy and 99.75% validation accuracy. We also evaluated the proposed system on a test set (new subjects) obtaining an accuracy of 77.85%. In addition, we showed the test prediction results for each gesture separately and analyzed which gestures for the Myo armband with our suggested network can be difficult to distinguish accurately. Moreover, we studied for first time the gated recurrent unit network capability in gesture recognition approaches. Finally, we integrated our method in a system that is able to classify live hand gestures.


Assuntos
Custos e Análise de Custo , Eletromiografia/economia , Eletromiografia/instrumentação , Gestos , Mãos/fisiologia , Humanos , Redes Neurais de Computação , Reconhecimento Automatizado de Padrão , Processamento de Sinais Assistido por Computador
19.
Neural Netw ; 172: 106081, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38181615

RESUMO

Synchronization between neural networks (NNs) has been intensively investigated to analyze stability, convergence properties, neuronal behaviors and response to various inputs. However, synchronization techniques of NNs with gated recurrent units (GRUs) have not been provided until now due to their complicated nonlinearity. In this paper, we address the sampled-data synchronization problems of GRUs for the first time, and propose controller design methods using discretely sampled control inputs to synchronize master and slave GRUs. The master and slave GRUs are mathematically modeled as a linear parameter varying (LPV) system in which the parameter of the slave GRUs is constructed independently of the master GRUs. This distinctive modeling feature provides flexibility to extend the existing master and slave NNs into a more general structure. Indeed, the sampled-data synchronization can be achieved by formulating the design condition in terms of linear matrix inequalities (LMIs). The novel sampled-data synchronization criteria are devised by combining the H∞ controller design with the looped-functional approach. The synthesized synchronization controllers guarantee not only asymptotic stability of the synchronization error system with aperiodic sampling, but also provides a satisfactory H∞ control performance. Moreover, the communication efficiency is improved by using the proposed method in which the sampled-data synchronization controller is combined with the event-triggered mechanism. Finally, the numerical example validates the proposed theoretical contributions via simulation results.


Assuntos
Redes Neurais de Computação , Simulação por Computador , Fatores de Tempo
20.
Sci Rep ; 14(1): 6269, 2024 03 15.
Artigo em Inglês | MEDLINE | ID: mdl-38491134

RESUMO

Soil health is essential for whirling stale soil into rich coffee-growing land. By keeping healthy soil, coffee producers may improve plant growth, leaf health, buds, cherry and bean quality, and yield. Traditional soil monitoring is tedious, time-consuming, and error-prone. Enhancing the monitoring system using AI-based IoT technologies for quick and precise changes. Integrated soil fertility control system to optimize soil health, maximize efficiency, promote sustainability, and prevent crop threads using real-time data analysis to turn infertile land into fertile land. The RNN-IoT approach uses IoT sensors in the coffee plantation to collect real-time data on soil temperature, moisture, pH, nutrient levels, weather, CO2 levels, EC, TDS, and historical data. Data transmission using a wireless cloud platform. Testing and training using recurrent neural networks (RNNs) and gated recurrent units gathered data for predicting soil conditions and crop hazards. Researchers are carrying out detailed qualitative testing to evaluate the proposed RNN-IoT approach. Utilize counterfactual recommendations for developing alternative strategies for irrigation, fertilization, fertilizer regulation, and crop management, taking into account the existing soil conditions, forecasts, and historical data. The accuracy is evaluated by comparing it to other deep learning algorithms. The utilization of the RNN-IoT methodology for soil health monitoring enhances both efficiency and accuracy in comparison to conventional soil monitoring methods. Minimized the ecological impact by minimizing water and fertilizer utilization. Enhanced farmer decision-making and data accessibility with a mobile application that provides real-time data, AI-generated suggestions, and the ability to detect possible crop hazards for swift action.


Assuntos
Fertilizantes , Solo , Agricultura , Fazendas , Poder Psicológico
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