Influence of oral health on the facial expressions and on the acupuncture examination in equines / Inflluência da saúde da cavidade oral na expressão facial e exame de acupuntura em equinos

The present study investigated the influence of oral health on horses' facial expression, reactivity of the acupuncture points and the perception of trainers and owners. We investigated 87 adult horses involved in sports or working activities. Pain was scored in person and by photography by an evaluator "blinded" to the animals' dental condition, using the Horse Grimace Scale (HGS). The acupuncture examination was performed by the same evaluator. Animals were evaluated before (T0) and 15 days (T1) after dental treatment. All horses included in the study had dental disorders. Statistically significant results were seen in median HGS scoring (3 vs. 1, p = 0.001) and number of reactive acupoints (11.2±5.6 vs. 4±2.9, p = 0.001). Additionally, complaints by the trainers/owners were lower at T1 compared with T0. There was a reduction in the pain reaction to application of pressure on following acupoints: dental point (44 vs. 4), Stomach-7 (31 vs. 3), Tiple-Heater (TH)-17 (27 vs. 4), and TH-16 (22 vs. 4). We concluded that acupuncture can be an adjunct method for diagnosis of dental disorders and treatment follow-up.

Este estudo avaliou a influência da saúde bucal na saúde geral de cavalos, por meio da expressão facial, do exame de acupuntura e da percepção geral dos treinadores/proprietários. Avaliaram-se 87 cavalos adultos, envolvidos em atividades esportivas ou de trabalho. A dor foi avaliada pela Horse Grimace Scale, presencialmente e por fotografia, por um avaliador que desconhecia a condição dos animais. Os exames de acupuntura foram realizados sempre pelo mesmo avaliador. As avaliações ocorreram antes (T0) e 15 dias (T1) após o tratamento odontológico. Todos os cavalos estudados apresentavam alterações odontológicas. Observou-se redução significativa na mediana do escore de dor (3 vs. 1, P = 0,001), no número de acupontos reativos (11,2±5,6 vs. 4±2,9, P = 0,001) e nas reclamações dos responsáveis em T1 em relação a T0. Também houve redução na sensibilidade nos acupontos 'ponto do dente' (44 vs. 4), estômago-7 (31 vs. 3), triplo aquecedor (TA)-17 (27 vs. 4) e TA-16 (22 vs. 4). Concluindo, o presente estudo mostrou que a acupuntura pode auxiliar no diagnóstico de problemas odontológicos e no acompanhamento pós-tratamento da cavidade bucal.

Assessment of thermal response, cardiorespiratory parameters and post-operative analgesia in dogs undergoing ovariohysterectomy with different combinations of epidural analgesia and isoflurane

This study aimed to evaluate the thermal response of the eyelids and lacrimal gland of the left eye (LETG) through infrared thermography (IRT), cardiorespiratory parameters, and their association with nociception and pain in bitches undergoing elective ovariohysterectomy (OVH) anesthetized with isoflurane and epidural analgesia. Twenty-one healthy bitches of different breeds were randomized into three groups receiving epidural blocks: GL (n=7), lidocaine (2 mg Kg-1 ); GLF (n=7), lidocaine (2 mg Kg-1 ) and fentanyl (3 µg Kg-1 ); and GLM (n=7), lidocaine (2 mg Kg-1 ) with morphine (0.1 mg Kg-1 ). IRT and cardiorespiratory parameters were evaluated at baseline (Ebasal), thirty minutes before anesthetic premedication, and at different surgical events: first incision (EInc), ligature and section of the left (ELoV), and right (ERoV) ovarian pedicle, ligature, and re-section of the cervix (EUt), and skin suture (ESut). The assessment of acute pain in the immediate post-operative period was registered at E1h, E2h, and E3h using IRT, the Dynamic Interactive Visual Analogic Scale (DIVAS), and the University of Melbourne Pain Scale (UMPS) scales. The results showed a statistically significant decrease in the lower eyelid surface temperature (LELT) during EInc for GL (32.9°C ± 0.62), in comparison to GLF (34.2°C ± 0.62) and GLM (35.3°C ± 0.62) (P = 0.006). Regarding LETG, a significant increase (P = 0.03) in the IRT of Ebasal (36.8°C ± 0.63) and EInc (36.1°C ± 0.63) for GLM was observed in comparison to the thermographic values for both perioperative events and groups. The GLM showed a significant decrease in IRT values of ERoV at E3h in the upper and lower eyelids (P = 0.03 and P = 0.01, respectively). A progressive and significant reduction of the IRT values of LETG was also recorded in GLM, with differences in ERoV (35.2 °C ± 0.63) (P = 0.02) and E3h (35.3 °C ± 0.63) (P = 0.01). The cardiovascular parameters (SAP, DAP, and MAP) did not differ between treatments, but in GL, there was a significant difference (P = 0.01) during EInc and ESut, compared to Ebasal. In the body temperature, EInc and ESut gradually decreased in all treatment groups (P = 0.01). In conclusion, hemodynamic and cardiorespiratory stability was associated with IRT readings and the absence of nociception. Changes in superficial temperature in the immediate post-operative period were lessened using isoflurane and epidural analgesia of lidocaine alone or in combination with pure opioids. These findings were clinically validated to the DIVAS and UMPS acute pain assessment scales.

Uso do carprofeno associado aos glicosaminoglicanos em cães com osteoartrite / Use of carprofen associated with glycosaminoglycans in dogs with osteoarthritis

O presente trabalho avaliou os efeitos analgésicos do carprofeno associado ou não à condroitina com glicosamina no tratamento de 26 cães com osteoartrite, distribuídos nos grupos: GT ­ carprofeno (Carproflan®); GTP ­ carprofeno e glicosaminoglicanos (Carproflan® e Procart®); e GC ­ somente analgésico (dipirona). A evolução dos pacientes foi classificada na escala de claudicação no dia do primeiro atendimento e aos 7, 14 e 21 dias. No GT, 60% dos animais apresentou melhora clínica a partir do 7º dia, 30% não alterou seu escore de claudicação e 10% apresentou êmese a partir do 7º dia, com suspensão da medicação. No GTP, 60% dos animais apresentou melhora clínica a partir do 7º dia, 30% não alterou seu escore de claudicação, 5% apresentou êmese a partir do 7º dia e 5% a partir do 14º dia, com suspensão da medicação. No GC, nenhum animal apresentou melhora clínica. Conclui-se que os animais submetidos ao tratamento com carprofeno apresentaram melhora na claudicação, principalmente quando associado aos glicosaminoglicanos.(AU)

The analgesic effects of carprofen associated or not with chondroitin with glucosamine were evaluated in the treatment of 26 dogs with osteoarthritis, distributed into groups: TG ­ carprofen (Carproflan®); PTG ­ carprofen and glycosaminoglycans (Carproflan® and Procart®); and CG ­ only analgesic (dipyrone). The evolution of patients was classified on the lameness scale on the first day of care and at 7, 14 and 21 days. In the TG, 60% of the animals showed clinical improvement from the 7th day, 30% did not change their lameness score and 10% had emesis from the 7th day, with discontinuation of the medication. In the PTG, 60% of the animals showed clinical improvement from the 7th day, 30% did not change their lameness score, 5% had emesis from the 7th day and 5% from the 14th day, with discontinuation of the medication. In the CG, no animal showed clinical improvement. It was concluded that animals undergoing treatment with carprofen showed improvement in lameness, especially when associated with glycosaminoglycans.(AU)

Focal spinal hyperesthesia as a prognostic factor in paraplegic dogs without deep pain perception / Hiperestesia espinhal focal como fator prognóstico em cães paraplégicos sem percepção de dor profunda

Intervertebral disc extrusion (IVDE) is the most common cause of spinal cord compression in dogs, whose prognosis is variable and depends on several factors, with deep pain perception (DPP) being the main parameter used. Investigations of new prognostic factors are studied to assist in the estimation of functional recovery. Thus, this study aimed to evaluate whether spinal hyperesthesia (SH) at the compression site can be used as a prognostic factor for the functional recovery of dogs with acute IVDE (Hansen type I), without DPP being subjected to thoracolumbar hemilaminectomy. Decompression surgery was performed on the same day or the day after admission. The duration of the loss of DPP until surgery performance ranged from 1 to 60 days, with a median of 4.5 days for the group of dogs with SH and 5.5 days for those without SH. Among the 68 dogs included in this retrospective study, 73.5% (50/68) showed SH, and 26.5% (18/68) were not identified. Recovery was satisfactory in 60% (30/50) of dogs with SH and in 27.7% (5/18) of dogs without SH, demonstrating that paraplegic dogs without DPP but with SH were 3.9 times more likely to recover when compared to dogs in the same condition, but with no SH. No studies have evaluated SH by palpation of the spine as a prognostic factor, which reinforces the relevance of the present study. The results of this study imply that SH in paraplegic dogs affected by thoracolumbar IVDE, without the presence of DPP, can be used as a possible prognostic indicator of functional recovery.

A extrusão do disco intervertebral (EDIV) é a causa mais comum de lesão compressiva na medula espinhal de cães, cujo prognóstico é variável e depende de diversos fatores, sendo a percepção de dor profunda (PDP) o principal parâmetro utilizado. Pesquisas de novos fatores prognósticos são estudados com intuito de auxiliar na estimativa mais precisa de recuperação funcional. Com isso, o objetivo do estudo foi avaliar se a hiperestesia espinhal (HE) no local da compressão, pode ser utilizada como um fator prognóstico para recuperação funcional de cães com extrusão aguda do disco intervertebral (Hansen tipo I), sem a presença de PDP submetidos a hemilaminectomia toracolombar. A cirurgia descompressiva ocorreu no mesmo dia ou no dia seguinte ao atendimento. A duração da perda de dor profunda até a realização da cirurgia variou de 1 a 60 dias, com uma mediana de 4,5 dias para o grupo de cães com e 5,5 dias para aqueles sem hiperestesia espinhal. Dos 68 cães incluídos nesse estudo retrospectivo, 73,5% (50/68) apresentavam HE e, em 26,5% (18/68) a dor não foi identificada. A recuperação foi satisfatória nos cães com HE em 60% (30/50) e, sem HE, em 27,7% (5/18) dos casos, demonstrando que os cães paraplégicos sem PDP, mas com presença de hiperestesia espinhal tem 3,9 vezes mais chances de recuperação quando comparado com cães na mesma condição, mas sem HE. Não foram encontrados trabalhos que avaliaram a HE mediante a palpação da coluna vertebral como um fator prognóstico, o que reforça a relevância do presente estudo. Os resultados do presente trabalho sugerem que a HE em cães paraplégicos acometidos por EDIV toracolombar sem presença de PDP pode ser utilizada como um possível indicador prognóstico de recuperação funcional.

Celecoxib in the treatment of orofacial pain and discomfort in rats subjected to a dental occlusal interference model

Purpose: To evaluate the effect of a selective cyclooxygenase 2 (COX-2) inhibitor on trigeminal ganglion changes and orofacial discomfort/nociception in rats submitted to an experimental model of dental occlusal interference (DOI). Methods: Female Wistar rats (180-200 g) were divided into five groups: a sham group (without DOI) (n=15); and four experimental groups with DOI treated daily with 0.1 mL/kg saline (DOI+SAL), 8, 16, or 32 mg/kg celecoxib (DOI+cel -8, -16, -32) (n=30/group). The animals were euthanized after one, three, and seven days. The bilateral trigeminal ganglia were analyzed histomorphometrically (neuron cell body area) and immunohistochemically (COX-2, nuclear factor-kappa B [NFkB], and peroxisome proliferator-activated receptor-y [PPARy]). A bilateral nociception assay of the masseter muscle was performed. The number of bites/scratches, weight, and grimace scale scores were determined daily. One-way/two-way analysis of variance (ANOVA)/Bonferroni post hoc tests were used (P < .05, GraphPad Prism 5.0). Results: DOI+SAL showed a reduction in neuron cell body area bilaterally, whereas DOI+cel-32 exhibited a significative increase in neuron cell body area compared with DOI+SAL group (P < 0.05). The ipsilateral (P=0.007 and P=0.039) and contralateral (P < 0.001 and P=0.005) overexpression of COX-2 and NFkB and downregulation of PPARy (P=0.016 and P < 0.001) occurred in DOI+SAL, but DOI+cel-32 reverted this alteration. DOI+SAL showed increase in isplateral (P < 0.001) and contralateral (P < 0.001) nociception, an increased number of bites (P=0.010), scratches (P < 0.001), and grimace scores (P=0.032). In the group of DOI+cel-32, these parameters were reduced. Conclusions: Celecoxib attenuated DOI-induced transitory nociception/orofacial discomfort resulting from trigeminal COX-2 overexpression.

Analgesia pós-operatória com Fentanil transdérmico ou Metadona intramuscular em cães submetidos à hemilaminectomia toracolombar / Postoperative analgesia with transdermal Fentanyl or intramuscular Methadone in dogs submitted to thoracolumbar hemilaminectomy

Background: Postoperative care after thoracolumbar hemilaminectomy in dogs generally includes rest, physical therapy,and analgesics such as opioids. Currently, there is no established standard for the management of postoperative pain inpatients undergoing hemilaminectomy. Ideally, an analgesic protocol should provide adequate pain relief with limited sedation, low adverse effects, and postoperative patient comfort. Therefore, this study aimed to evaluate postoperative analgesiausing transdermal fentanyl or intramuscular methadone in dogs undergoing thoracolumbar hemilaminectomy associatedwith intervertebral disc fenestration (HT) for the treatment of intervertebral disc extrusion (IVDE).Materials, Methods & Results: Eight dogs from the Department of Neurology and Neurosurgery of a Veterinary TeachingHospital, submitted to HT for the treatment of IVDE, were included. The dogs were randomly distributed into 2 groups ofequal numbers, namely the transdermal fentanyl (FT) group and the intramuscular methadone (IM) group. At the end ofthe surgical procedure, a fentanyl adhesive patch was applied to the animals in the FT group, which remained there for 72h. In the IM group, analgesia was induced by intramuscular administration of methadone at intervals of 6 h until 72 h aftersurgery. The animals were evaluated using the short form of the Glasgow Composite Measure Pains Scale (CMPS-SF).Evaluations of physiological parameters, side effects, and pain were performed by 2 assessors who had experience usingthe pain scale and were blinded to the analgesic protocol. Pain evaluations were performed every 2 h (from T4) until 24h after the surgical procedure. Evaluations were performed every 4 h from 24 h to 48 h after the surgical procedure and...

Associação do bloqueio do plano transverso e serrátil em gata submetida à mastectomia / Association of transversus and serratus plane block in cat submitted to mastectomy

Os bloqueios locorregionais são considerados padrão-ouro para a analgesia perioperatória. Sendo assim, este trabalho apresenta o efeito da associação do bloqueio do plano transverso do abdome com o bloqueio do plano serrátil em um felino de 11 anos, fêmea, que foi submetido à mastectomia unilateral. Foi utilizada a metadona 0,3 mg/kg via intramuscular (IM) na medicação pré-anestésica e propofol dose-efeito via intravenosa (IV) para indução, enquanto a manutenção foi feita com isoflurano. O TAP Block e o SP-Block foram realizados unilateralmente utilizando a associação de bupivacaína 0,3mL/kg, em cada ponto, diluída a 0,25% com solução fisiológica. A frequência cardíaca (FC), a frequência respiratória (f), a pressão arterial não invasiva (Método Doppler), a temperatura esofágica (oC), a saturação de oxigênio (SpO2), a capnografia (EtCO2) e o eletrocardiograma foram monitorados continuamente e registrados a cada dez minutos. A paciente foi monitorada por cinco horas, após a extubação, quanto à dor, sendo utilizada, para isso, a Escala Multidimensional de Dor Aguda (UNESP-Botucatu). A recuperação anestésica da paciente foi rápida e sem complicações. Durante a avaliação de dor, o animal apresentou escore zero, não manifestando qualquer desconforto pós-operatório. A associação das técnicas foi eficaz no bloqueio anestésico das paredes torácica e abdominal, sugerindo a inclusão destas nos protocolos de analgesia multimodal para esse tipo de cirurgia.

Locoregional blocks are considered the gold standard for perioperative analgesia. Thus, this paper presents the effect of the association of transverse abdominal plane block with serratus plane block in an 11-year-old female feline submitted to unilateral mastectomy. Methadone 0.3 mg/kg via intramuscular (IM) was used as pre anesthetic medication and dose-effect propofol via intravenous (IV) was used for induction, while the maintenance was done with isofluorane. TAP Block and SP-Block were performed unilaterally using an association of Bupivacaine 0.3 ml/kg at each point, diluted to 0.25% with saline solution. Heart rate (HR), respiratory rate (f), non-invasive blood pressure (Doppler method), esophageal temperature (oC), oxygen saturation (SpO2), capnography (EtCO2), and electrocardiogram were monitored continuously and recorded every 10 minutes. The patient was monitored for pain during five hours after extubation using the Multidimensional Scale of UNESP-Botucatu. The anesthetic recovery of the patient was fast and without complications. During pain assessment, the animal presented a score of zero and did not present any postoperative discomfort. The association of techniques was effective in the anesthetic blockade of the thoracic and abdominal walls, suggesting their inclusion in multimodal analgesia protocols for this type of surgery.

Bloqueio do plano serrátil associado ao transverso do abdômen na mastectomia total unilateral em cadela / Blocking of the Serratus Plan associated with the Transverse Abdominis in a total unilateral mastectomy in bitch

A anestesia locorregional, em pequenos animais, está em crescente utilização como forma de promover analgesia para procedimentos cirúrgicos, através do bloqueio reversível da condução do impulso nervoso. Assim, o objetivo deste trabalho foi relatar o uso do bloqueio locorregional do plano serrátil (SP block) associado ao bloqueio locorregional do plano transverso do abdômen (TAP block) em uma cadela da raça Lhasa Apso. A associação de tais bloqueios visou à insensibilização da musculatura na região da cadeia mamária para um procedimento cirúrgico de mastectomia unilateral total. A cadela castrada, foi encaminhada para a mastectomia unilateral total direita, apresentando nódulos nas glândulas mamárias torácica caudal e inguinal. Os bloqueios foram realizados com a paciente em decúbito dorsal, utilizando-se bupivacaína a 0,25%. Em seguida, a paciente foi liberada para o procedimento, o qual foi monitorado. Os parâmetros de eletrocardiografia, frequência respiratória, frequência cardíaca, oximetria de pulso, pressão arterial oscilométrica (composta por pressão arterial sistólica, pressão arterial diastólica e pressão arterial média), capnografia e temperatura esofágica foram anotados a cada dez minutos em uma ficha de avaliação anestésica. Durante a recuperação pós-operatória, foi realizada a avaliação de dor aguda por meio da escala de dor da Universidade de Melbourne. Os resultados demonstram que a associação do TAP block com o SP block foi eficiente em promover analgesia para uma mastectomia total unilateral de cadela.

Locoregional anesthesia in small animals is increasingly used as a way to promote analgesia for surgical procedures, through a reversible block of nerve impulse conduction. Thus, the objective of this study was to report the use of locoregional block of the serratus plane (SP block) associated with the locoregional block of the transverse abdominis plane (TAP block) in a bitch of the Lhasa Apso breed. The association of such blocks aimed to desensitize the musculature in the region of the mammary chain for a surgical procedure of total unilateral mastectomy. The castrated bitch was referred for total right unilateral mastectomy, showing nodules in the caudal thoracic and inguinal mammary glands. The blocks were performed with the patient in dorsal decubitus, using 0.25% bupivacaine. Then, the patient was released for the procedure, which was monitored. The parameters of electrocardiography, respiratory rate, heart rate, pulse oximetry, oscillometric blood pressure (composed of systolic blood pressure, diastolic blood pressure, and mean blood pressure), capnography, and esophageal temperature were recorded every 10 minutes in an anesthetic evaluation form. During the postoperative recovery, acute pain was evaluated using the pain scale of the University of Melbourne. The results demonstrate that the association of TAP block with SP block was efficient in promoting analgesia for a total unilateral mastectomy in a bitch.

Closure of defects in a geometric figure pattern associated with tumescent anesthesia with lidocaine in rabbits (Oryctolagus cuniculus) / Fechamento de defeitos em padrão de figura geométrica associado ao emprego de anestesia por tumescência com lidocaína em coelhos (Oryctolagus cuniculus)

The use of tumescent anesthesia with lidocaine can provide better intra- and postoperative analgesia that would benefit extensive reconstructive surgery. However, lidocaine can interfere with the healing process. Therefore, this study aimed to assess the local interference of the healing of induced and closed skin defects in a geometric pattern associated with the use of tumescent anesthesia with lidocaine in rabbits. Furthermore, we assessed its influence on cardiorespiratory parameters and postoperative analgesia. This study included 27 rabbits divided into three groups: GC (without the use of tumescence), GS (use of tumescence with 0.9% NaCl solution), and GL (use of tumescent anesthesia with lidocaine). There was no statistically significant intergroup difference in any stage of the wound healing process on macroscopic evaluations, in the angiogenesis process, or in the process of collagenization and fibroblast deposition. There were significant differences in heart rate (lower in GL), respiratory rate (higher in GC), mean arterial pressure (higher in GL), and expired concentration of isoflurane (lower in GL). There was no significant intergroup difference in the von Frey filament test or the visual analog scale score used to evaluate postoperative analgesia. We concluded that tumescent anesthesia with lidocaine does not impair postoperative tissue repair. Its use features benefits such as reducing the volume of inhaled anesthetic, maintaining the anesthesia plan, stable heart and respiratory rates, and lower hypotension during the surgical procedure.

O uso da anestesia por tumescência com lidocaína pode proporcionar melhor analgesia transoperatória e pós-operatória, o que seria um benefício em cirurgias reconstrutivas extensas. Entretanto, a lidocaína pode interferir na cicatrização. Diante disso, delineou-se um estudo a fim de avaliar a interferência local da cicatrização de defeitos cutâneos induzidos e fechados em padrão de figura geométrica, associado ao emprego de anestesia por tumescência com lidocaína em coelhos. Ademais, avaliar sua influência em parâmetros cardiorrespiratórios e na analgesia pós-operatória. Foi realizado um estudo com 27 coelhos, separados em três grupos, compreendidos em GC (sem o emprego de tumescência), GS (emprego de tumescência com solução NaCl 0.9%) e GL (emprego de anestesia por tumescência com lidocaína). Não houve diferença estatística em nenhuma etapa do processo cicatricial da ferida entre os grupos, tampouco nas avaliações macroscópicas, e no processo de angiogênese, ou ainda no processo de colagenização e deposição de fibroblastos. Houve diferença significativa na frequência cardíaca (menor no GL) e na respiratória (maior no GC), na pressão arterial média (maior no GL) e na concentração expirada de isoflurano (menor no GL). Não houve diferença significativa entre os grupos no teste de filamentos de von Frey e na Escala Visual Analógica, utilizados para avaliar a analgesia pós-operatória. Conclui-se que anestesia por tumescência com lidocaína não prejudica a regeneração tecidual após a cirurgia. O seu uso oferece benefícios como a diminuição do volume de anestésico inalatório, manutenção do plano anestésico, estabilidade das frequências cardíaca e respiratória, além de menor hipotensão durante o procedimento cirúrgico.

Pathophysiology of pain and use of opioids in cattle / Fisiopatogenia da dor e uso de opioides em bovinos / Fisiopatología del dolor y uso de opioides en bovinos

O controle da dor é uma área que atualmente vem ganhando grande importância, principalmente para a bovinocultura. Determinar a origem e as causas do processo doloroso é uma tarefa que demanda grande atenção por parte dos profissionais, especialmente para que possam intervir da melhor maneira possível, além de buscar remover os fatores que incitaram, atuar na prevenção e tratamento do mecanismo da dor com uso de diversos fármacos disponíveis no mercado. O uso de opioides vem sendo alvo de estudos como estratégia farmacológica para controle e manejo do sofrimento animal, fato este que induz graves perdas e prejuízos para a produção bovina, a nível produtivo, reprodutivo e econômico. No entanto, faz-se necessário cada vez mais novos estudos a respeito dos benefícios que eles podem proporcionar aos bovinos, uma vez que existem alguns limitantes como custo e efeitos adversos.

Pain control is an area that is currently gaining great importance, mainly for beef production. Determining the origin and causes of the painful process is a task that demands great attention from professionals, especially so that they can intervene in the best possible way. In addition to seeking to remove the factors that prompted them, they act in the prevention and treatment of the pain mechanism with the use of various drugs available on the market. The use of opioids has been the subject of studies as a pharmacological strategy for the control and management of animal suffering, a fact that induces serious losses and losses for bovine production, at the productive, reproductive and economic level. However, more and more studies are needed regarding the benefits they can provide to cattle, since there are some limitations such as cost and adverse effects.

El control del dolor es un área que está cobrando gran importancia en la actualidad, especialmente para la ganadería. Determinar el origen y las causas del proceso doloroso es una tarea que requiere una gran atención por parte de los profesionales, especialmente para que puedan intervenir de la mejor manera posible, además de buscar remover los factores que los incitaron, actuando en la prevención y tratamiento del mecanismo del dolor mediante el uso de diversos fármacos disponibles en el mercado. El uso de opioides ha sido objeto de estudios como estrategia farmacológica para el control y manejo del sufrimiento animal, hecho que induce graves pérdidas y pérdidas para la producción bovina, a nivel productivo, reproductivo y económico. Sin embargo, se necesitan cada vez más estudios sobre los beneficios que pueden brindar al ganado, ya que existen algunas limitaciones como el costo y los efectos adversos.

Pathophysiology of pain and use of opioids in cattle / Fisiopatogenia da dor e uso de opioides em bovinos / Fisiopatología del dolor y uso de opioides en bovinos

O controle da dor é uma área que atualmente vem ganhando grande importância, principalmente para a bovinocultura. Determinar a origem e as causas do processo doloroso é uma tarefa que demanda grande atenção por parte dos profissionais, especialmente para que possam intervir da melhor maneira possível, além de buscar remover os fatores que incitaram, atuar na prevenção e tratamento do mecanismo da dor com uso de diversos fármacos disponíveis no mercado. O uso de opioides vem sendo alvo de estudos como estratégia farmacológica para controle e manejo do sofrimento animal, fato este que induz graves perdas e prejuízos para a produção bovina, a nível produtivo, reprodutivo e econômico. No entanto, faz-se necessário cada vez mais novos estudos a respeito dos benefícios que eles podem proporcionar aos bovinos, uma vez que existem alguns limitantes como custo e efeitos adversos.(AU)

Pain control is an area that is currently gaining great importance, mainly for beef production. Determining the origin and causes of the painful process is a task that demands great attention from professionals, especially so that they can intervene in the best possible way. In addition to seeking to remove the factors that prompted them, they act in the prevention and treatment of the pain mechanism with the use of various drugs available on the market. The use of opioids has been the subject of studies as a pharmacological strategy for the control and management of animal suffering, a fact that induces serious losses and losses for bovine production, at the productive, reproductive and economic level. However, more and more studies are needed regarding the benefits they can provide to cattle, since there are some limitations such as cost and adverse effects.(AU)

El control del dolor es un área que está cobrando gran importancia en la actualidad, especialmente para la ganadería. Determinar el origen y las causas del proceso doloroso es una tarea que requiere una gran atención por parte de los profesionales, especialmente para que puedan intervenir de la mejor manera posible, además de buscar remover los factores que los incitaron, actuando en la prevención y tratamiento del mecanismo del dolor mediante el uso de diversos fármacos disponibles en el mercado. El uso de opioides ha sido objeto de estudios como estrategia farmacológica para el control y manejo del sufrimiento animal, hecho que induce graves pérdidas y pérdidas para la producción bovina, a nivel productivo, reproductivo y económico. Sin embargo, se necesitan cada vez más estudios sobre los beneficios que pueden brindar al ganado, ya que existen algunas limitaciones como el costo y los efectos adversos.(AU)

Complete avulsion of the hoof capsule and subsequent testicular degeneration in a criollo stallion

Background: Complete avulsion of the hoof in horses, also known as exungulation, is not a commonly reported injury and usually leads to euthanasia due to the great amount of tissue loss, intense pain, secondary complications, expensive and lengthy treatment. It can involve deep structures and cause different complications leading to chronic lameness. In stallions affected by such injury, the reproductive tract and performance may also be affected. The aim of this study was to report a case of complete avulsion of the right front hoof in a Criollo stallion and subsequent bilateral testicular degeneration. Case: A 10-year-old Criollo stallion was referred to the Veterinary Clinical Hospital of the Federal University of Pelotas (HCV- UFPel) with a complete avulsion of the left front hoof. At admission, the stallion had clinical parameters compatible with intense pain and blood loss. Evaluation of the wound demonstrated that the distal end of the third phalanx (P3) was exposed but no fracture was detected on radiological evaluation. No other structure was apparently affected. Initially, anti-inflammatory (phenylbutazone) and opioid (morphine) was given for pain control and supportive fluid therapy was started to restore hydration. Antibiotic (Sulfamethoxazole with trimethoprim) was administered for 10 days. Continued therapy with phenylbutazone, pentoxifylline, omeprazole and supplementation with methionine, biotin and zinc was also given. Local treatment was carried out by cleaning the wound, applying an antimicrobial ointment and dressing it with a bandage. Wound management was adapted according to the evolution and healing process. The stallion was kept in stall rest during its hospitalization time. In the second month after the injury, accumulation of liquid in the scrotum was observed. Clinical and ultrasound evaluation lead to a presumptive diagnosis of testicular degeneration. The stallion was discharged after three months when the wound was almost healed and the hoof had started to grow. Six month later, a follow up by the referring vet showed that the hoof was almost completely grown and the x-ray assessment demonstrated a dorsal rotation and resorption of the distal end of the third phalanx. Discussion: The stallion of this report had a complete avulsion of the hoof capsule caused by trauma. Conservative treatment was established including wound cleaning and dressing to avoid contamination, control of pain and inflammation, antimicrobial care and supplementation to support hoof growth. Time period for wound healing and hoof growth was in agreement with other cases described previously. Bone sequestrum of the distal end of the third phalanx, and detachment of a fragment were observed in this case, followed by bone resorption. The stallion was closely monitored to prevent laminitis in the contralateral limb and no alterations were detected during the treatment period. Testicular degeneration was observed, probably caused as a consequence of hoof avulsion and due to a long period of stall rest. Degenerative alterations in testicles interfere with thermoregulation and spermatogenesis, affecting semen quality and reproductive performance. Rotation of the third phalanx was also observed six months later caused by the hoof loss. In conclusion, the patient of this report had a complete regrowth of the hoof capsule although a long intensive treatment was necessary to achieve this result. As a consequence, testicles degeneration may happen impairing its function as a stallion.(AU)

Effects of parasites and predators on nociception: decreases analgesia reduces overwinter survival in root voles (Rodentia: Cricetidae)

ABSTRACT Growing evidence suggests that parasite-infected prey is more vulnerable to predation. However, the mechanism underlying this phenomenon is obscure. In small mammals, analgesia induced by environmental stressors is a fundamental component of the defensive repertoire, promoting defensive responses. Thus, the reduced analgesia may impair the defensive ability of prey and increase their predation risk. This study aimed to determine whether coccidia infection increases the vulnerability to predation in root voles, Microtus oeconomus (Pallas, 1776), by decreased analgesia. Herein, a predator stimulus and parasitic infection were simulated in the laboratory via a two-level factorial experiment, then, the vole nociceptive responses to an aversive thermal stimulus were evaluated. Further, a field experiment was performed to determine the overwinter survival of voles with different nociceptive responses via repeated live trapping. The coccidia-infected voles demonstrated reduced predator-induced analgesia following exposure to predator odor. Meanwhile, pain-sensitive voles had lower overwinter survival than pain-inhibited voles in enclosed populations throughout the duration of the experiment. Our findings suggest that coccidia infection attenuates predator-induced analgesia, resulting in an increased vulnerability to predation.

Comparison of intraoperative nociception and postoperative acute pain after traditional or minimally invasive ovariohysterectomy in dogs

Many variations of ovariohysterectomy techniques have been described, including the traditional one and minimally invasive procedures. Non-laparoscopic Snook hook technique is an alternative for performing minimally invasive ovariohysterectomy. Few studies have been carried out in order to assess pain in animals submitted to minimally invasive surgeries, especially involving one of the most performed surgical procedures in veterinary practice. The aim of this study was to evaluate surgical duration, intraoperative nociception and acute postoperative pain after traditional ovariohysterectomy or minimally invasive non-laparoscopic technique in dogs using Snook hook. The hypothesis is that non-laparoscopic minimally invasive ovariohysterectomy would be faster and less painful than the conventional technique. Thirty dogs were divided into Traditional Group (TG = 15) and Minimally Invasive Group (MIG = 15). Heart rate, respiratory rate, systolic blood pressure, body temperature, oxyhemoglobin saturation, end-tidal carbon dioxide concentration (ETCO2) and end-tidal isoflurane concentration were evaluated before the surgery begins (M0), during incision (M1), clamping of the first ovarian pedicle (M2), second ovarian pedicle (M3), uterine cervix (M4), abdominal suture (M5) and at the end of surgery (M6). The modified Glasgow Pain Scale was used for acute postoperative pain assessment and Visual Analogue Scale (VAS) was used to assess the sensitivity of surgical wound. The level of significance established for all statistical analysis was 5%. Statistical differences were not observed between groups considering total surgical time and postoperative acute pain intensity (P > 0.05), in spite of MIG having shorter duration of surgery. There was no statistical difference between groups considering all intraoperative parameters except respiratory rate (TG < MIG; P < 0.05) and ETCO2 (MIG < TG; P < 0.05) at the moment of traction of the first ovarian pedicle (M2). Pain assessment by VAS showed statistical difference 24h after the end of surgery (TG < MIG) (P < 0.05). Both procedures were similar regarding intraoperative nociception and acute postoperative pain. It is possible that the sensation of pain in both procedures was blocked by the effectiveness of analgesics, once they might cause an inhibition of painful behaviors limiting a possible difference in pain identification. Higher respiratory stress observed in MIG at M2 and higher pain score by VAS noted in MIG 24 h after the end of surgery can be justified by greater traction of ovarian pedicle, due to limited surgical access of minimally invasive technique. Minimally invasive ovariohysterectomy non-laparoscopic seems to be potentially faster, probably due to the smaller size of the abdominal incision, which takes less time to be closed. In the present study, both techniques were performed by an experienced surgeon, providing safe procedures, nevertheless it is important to emphasize that iatrogenic injury can be caused by surgeons non-proficient in the Snook hook technique, considering the limited visualization of anatomical abdominal structures. Data obtained indicate that traditional ovariohysterectomy and non-laparoscopic Snook hook technique promote similar intraoperative nociception and acute postoperative pain, however minimally invasive procedure is potentially faster with less surgical trauma.(AU)

Postoperative evaluation of analgesia promoted by the use of dexmedetomidine alone and associated with morphine as an intramuscular pre-anesthetic medication in bitches submitted for ovariohysterectomy / Avaliação pós-operatória da analgesia promovida pelo uso da dexmedetomidina isolada e associada à morfina em cadelas submetidas à ovariohisterectomia

This study aimed to evaluate the postoperative analgesic efficacy of dexmedetomidine alone and when associated with morphine in patients under general inhalational anesthesia with isoflurane and undergoing elective ovariohysterectomy (OH). Twenty healthy bitches were selected via physical and laboratory examinations. Prior to the study, they underwent a 24-h period of adaptation to the environment and observers. They were then randomly divided into two groups: the dexmedetomidine group receiving a dose of 10 µg/kg, and dexmedetomidine group (10 µg/kg) associated with morphine receiving a dose of 0.3 mg/kg, administered via the intramuscular route. Thereafter, patients were induced with propofol and maintained with isoflurane diluted in 100% oxygen administered through a calibrated vaporizer. To verify postoperative analgesia, pain assessments were performed using the modified Glasgow (EGM) and Melbourne (EM) scales. For sedation assessment, the Dobbins scale was used at different times: before the administration of pre-anesthetic medication (T0) and at another six times in the postoperative period, 1 (T1), 2 (T2), 4 (T3), 8 (T4), 12 (T5), and 24 (T6) h after orotracheal extubation. No statistical differences were observed between groups in the scales according to Dunn's Kruskal-Wallis post hoc test, and between the times a statistical difference was noticed by the Friedman test (p<0.05) for the EGM and EM scale scores, but there was no need for analgesic rescue. Therefore, we found that isolated dexmedetomidine and morphine produced adequate analgesic effects in the postoperative period of bitches submitted for OH.

Objetivou-se avaliar a eficácia analgésica pós-operatória da dexmedetomidina isolada e associada à morfina em pacientes submetidas à anestesia geral inalatória com isoflurano e submetidas à ovariohisterectomia eletiva (OH). Vinte cadelas saudáveis foram selecionadas a partir de exames físico e laboratoriais. Previamente ao estudo, foram submetidas a um período de 24 horas de adaptação ao ambiente e aos observadores. Ato contínuo, foram divididas aleatoriamente em dois grupos: grupo dexmedetomidina, na dose de 10 µg/Kg (GD) e grupo dexmedetomidina (10 µg/Kg) associado com morfina, na dose de 0,3 mg/Kg (GDM), administrados pela via intramuscular (IM). Ato contínuo, as pacientes foram induzidas com propofol e mantidas com isoflurano diluído em oxigênio 100% e administrado através de vaporizador calibrado. Para verificação da analgesia pós-operatória foram realizadas avaliações de dor por meio de escalas de Glasgow Modificada (EGM) e de Melbourne (EM). Para avaliação de sedação, por meio da escala de Dobbins (ED), em diferentes tempos: antes da administração da MPA (T0), e em mais 6 tempos no período pós-operatório, uma (T1), duas (T2), quatro (T3), oito (T4), 12 (T5) e 24 (T6) horas após a extubação orotraqueal. Não foram observadas diferenças estatísticas entre os grupos nas escalas de acordo com o teste de Kruskal-Wallis post-hoc de Dunn; e entre os tempos notou-se diferença estatística pelo teste de Friedman (p<0,05) para EGM e EM, porém não houve necessidade de resgate analgésico. Portanto, conclui-se que a dexmedetomidina isolada e associada a morfina produziu efeito analgésico adequado no período pós-operatório de cadelas submetidas a OH.

The need for opioid in the postoperative analgesia of dogs undergoing hemilaminectomy due to intervertebral disc extrusion

ABSTRACT: The aim of this study was to evaluate the postoperative analgesic effect of protocols with and without the opioid methadone in dogs with intervertebral disc extrusion undergoing decompressive surgery. Sixteen paraplegic dogs with preserved nociception underwent hemilaminectomy/disc fenestration and were randomly assigned to two groups. The analgesic protocol consisted of methadone, meloxicam and dipyrone in Group I (G1), and meloxicam and dipyrone in Group II (G2). The animals were blindly assessed by two observers, using the visual analogue scale (VAS) and the short-form Glasgow Composite Measure Pain Scale (CMPS-SF). Assessments occurred every 2 hours during first 24 hours post-surgery, and every 4 hours afterwards. There was no statistical difference among groups regarding pain scores or analgesic rescues. Both analgesic protocols provided analgesia in the initial 48 hours postoperatively, demonstrating that opioids are not necessary in the postoperative period of dogs undergoing hemilaminectomy and disc fenestration.

RESUMO: O objetivo deste estudo foi avaliar a analgesia pós-operatória de protocolos com e sem o opioide metadona em cães com extrusão de disco intervertebral submetidos à descompressão cirúrgica. Dezesseis cães paraplégicos com presença de nocicepção foram submetidos à hemilaminectomia/fenestração de disco e distribuídos aleatoriamente em dois grupos. No Grupo I (G1), o protocolo analgésico consistiu em metadona, meloxicam e dipirona e, no Grupo II (G2), por meloxicam e dipirona. Os pacientes foram avaliados de maneira cega por dois avaliadores, com base na escala visual analógica (EVA) e na escala simplificada composta de dor de Glasgow (CMPS-SF). As avaliações ocorreram a cada 2 horas durante as primeiras 24 horas de pós-operatório e, por mais 24 horas, a cada 4 horas. Não houve diferença estatística entre os grupos avaliados em relação à escores de dor e nem a necessidade de resgate analgésico. Ambos os protocolos promoveram analgesia nas 48 horas iniciais de pós-operatório, demonstrando não haver a necessidade do uso de opioide em cães submetidos à hemilaminectomia e fenestração de disco.

Postoperative analgesic effects of Reiki therapy in bitches undergoing ovariohysterectomy / Efeito analgésico pós-operatório da terapia Reiki em cadelas submetidas a ovariohisterectomia

ABSTRACT: This study aimed to evaluate the effects of Reiki therapy on postoperative pain in bitches undergoing elective minimally invasive ovariohysterectomy (OVH). Thirty bitches were randomly assigned to three groups: Control, Placebo, or Reiki. All dogs received methadone as preanesthetic medication (PAM), meloxicam in the preoperative period, propofol for anesthetic induction, and isoflurane for anesthetic maintenance. Immediately after OVH, the dogs in the Reiki were submitted to a single session of Reiki therapy, dogs in the Placebo received simulated Reiki therapy from a non-therapist, and dogs in the Control received no treatment. All dogs were evaluated for pain using short-form Glasgow composite measure pain scale (CMPS-SF) and visual analog scale (VAS) before (M0) and 2 (M2), 4 (M4), 8 (M8), 12 (M12), and 24 hours (M24) after administration of PAM. Comparing the CMPS-SF scores between the groups, at M2 Reiki scores were lower than those of the Placebo and at M4 those in the Reiki were lower than those of the Control or Placebo groups. Comparing the VAS scores, at M4 and M8, Reiki scores were lower than those of the Control or Placebo groups. Additional analgesia (morphine 0.2 mg.kg-1 intramuscularly) was administered to three bitches in Control and to four bitches of the Placebo. Reiki did not require additional opioid analgesia in the postoperative period. It was concluded that Reiki therapy provided analgesic effect and contributed to improve postoperative comfort of bitches submitted to elective OVH.

RESUMO: Este estudo teve o objetivo de avaliar os efeitos da terapia Reiki na dor do período pós-operatório de cadelas submetidas à ovariohisterectomia (OVH) eletiva pelo método minimamente invasivo com gancho. Para isso, foram utilizadas 30 cadelas alocadas aleatoriamente em três grupos experimentais: Controle, Placebo e Reiki. Todos os animais receberam metadona como medicação pré-anestésica (MPA), meloxicam, propofol na indução anestésica e isofluorano na manutenção anestésica. Imediatamente após a OVH, os animais do Reiki foram submetidos a uma única sessão de Reiki, os animais do Placebo receberam uma simulação da terapia Reiki por um indivíduo não terapeuta e os animais do Controle não receberam nenhum tratamento. Os animais foram avaliados por meio da forma curta da escala de dor de Glasgow (CMPS-SF) e da escala visual analógica (EVA) antes da administração da MPA (M0) e 2h (M2), 4h (M4), 8h (M8), 12h (M12) e 24h (M24) após a MPA. Comparando-se os valores obtidos pela CMPS-SF, em M2, os valores do Reiki foram menores que do Placebo e, em M4, os valores do Reiki foram menores que do Controle e do Placebo. Observando-se os dados obtidos com a EVA, em M4 e M8, os valores do Reiki foram menores que do Controle e do Placebo. Foi administrada analgesia adicional (0,2 mg.kg-1 de morfina por via intramuscular) em três animais do Controle e em quatro animais do Placebo. Os animais do Reiki não necessitaram de analgesia adicional no período pós-operatório. Concluiu-se que a terapia Reiki contribuiu com a analgesia e o conforto pós-operatório de cadelas submetidas à OVH eletiva.

Postoperative analgesic effects of Reiki therapy in bitches undergoing ovariohysterectomy / Efeito analgésico pós-operatório da terapia Reiki em cadelas submetidas a ovariohisterectomia

This study aimed to evaluate the effects of Reiki therapy on postoperative pain in bitches undergoing elective minimally invasive ovariohysterectomy (OVH). Thirty bitches were randomly assigned to three groups: Control, Placebo, or Reiki. All dogs received methadone as preanesthetic medication (PAM), meloxicam in the preoperative period, propofol for anesthetic induction, and isoflurane for anesthetic maintenance. Immediately after OVH, the dogs in the Reiki were submitted to a single session of Reiki therapy, dogs in the Placebo received simulated Reiki therapy from a non-therapist, and dogs in the Control received no treatment. All dogs were evaluated for pain using short-form Glasgow composite measure pain scale (CMPS-SF) and visual analog scale (VAS) before (M0) and 2 (M2), 4 (M4), 8 (M8), 12 (M12), and 24 hours (M24) after administration of PAM. Comparing the CMPS-SF scores between the groups, at M2 Reiki scores were lower than those of the Placebo and at M4 those in the Reiki were lower than those of the Control or Placebo groups. Comparing the VAS scores, at M4 and M8, Reiki scores were lower than those of the Control or Placebo groups. Additional analgesia (morphine 0.2 mg.kg-1 intramuscularly) was administered to three bitches in Control and to four bitches of the Placebo. Reiki did not require additional opioid analgesia in the postoperative period. It was concluded that Reiki therapy provided analgesic effect and contributed to improve postoperative comfort of bitches submitted to elective OVH.

Este estudo teve o objetivo de avaliar os efeitos da terapia Reiki na dor do período pós-operatório de cadelas submetidas à ovariohisterectomia (OVH) eletiva pelo método minimamente invasivo com gancho. Para isso, foram utilizadas 30 cadelas alocadas aleatoriamente em três grupos experimentais: Controle, Placebo e Reiki. Todos os animais receberam metadona como medicação pré-anestésica (MPA), meloxicam, propofol na indução anestésica e isofluorano na manutenção anestésica. Imediatamente após a OVH, os animais do Reiki foram submetidos a uma única sessão de Reiki, os animais do Placebo receberam uma simulação da terapia Reiki por um indivíduo não terapeuta e os animais do Controle não receberam nenhum tratamento. Os animais foram avaliados por meio da forma curta da escala de dor de Glasgow (CMPS-SF) e da escala visual analógica (EVA) antes da administração da MPA (M0) e 2h (M2), 4h (M4), 8h (M8), 12h (M12) e 24h (M24) após a MPA. Comparando-se os valores obtidos pela CMPS-SF, em M2, os valores do Reiki foram menores que do Placebo e, em M4, os valores do Reiki foram menores que do Controle e do Placebo. Observando-se os dados obtidos com a EVA, em M4 e M8, os valores do Reiki foram menores que do Controle e do Placebo. Foi administrada analgesia adicional (0,2 mg.kg-1 de morfina por via intramuscular) em três animais do Controle e em quatro animais do Placebo. Os animais do Reiki não necessitaram de analgesia adicional no período pós-operatório. Concluiu-se que a terapia Reiki contribuiu com a analgesia e o conforto pós-operatório de cadelas submetidas à OVH eletiva.

Postoperative analgesic effects of Reiki therapy in bitches undergoing ovariohysterectomy / Efeito analgésico pós-operatório da terapia Reiki em cadelas submetidas a ovariohisterectomia

This study aimed to evaluate the effects of Reiki therapy on postoperative pain in bitches undergoing elective minimally invasive ovariohysterectomy (OVH). Thirty bitches were randomly assigned to three groups: Control, Placebo, or Reiki. All dogs received methadone as preanesthetic medication (PAM), meloxicam in the preoperative period, propofol for anesthetic induction, and isoflurane for anesthetic maintenance. Immediately after OVH, the dogs in the Reiki were submitted to a single session of Reiki therapy, dogs in the Placebo received simulated Reiki therapy from a non-therapist, and dogs in the Control received no treatment. All dogs were evaluated for pain using short-form Glasgow composite measure pain scale (CMPS-SF) and visual analog scale (VAS) before (M0) and 2 (M2), 4 (M4), 8 (M8), 12 (M12), and 24 hours (M24) after administration of PAM. Comparing the CMPS-SF scores between the groups, at M2 Reiki scores were lower than those of the Placebo and at M4 those in the Reiki were lower than those of the Control or Placebo groups. Comparing the VAS scores, at M4 and M8, Reiki scores were lower than those of the Control or Placebo groups. Additional analgesia (morphine 0.2 mg.kg-1 intramuscularly) was administered to three bitches in Control and to four bitches of the Placebo. Reiki did not require additional opioid analgesia in the postoperative period. It was concluded that Reiki therapy provided analgesic effect and contributed to improve postoperative comfort of bitches submitted to elective OVH.(AU)

Este estudo teve o objetivo de avaliar os efeitos da terapia Reiki na dor do período pós-operatório de cadelas submetidas à ovariohisterectomia (OVH) eletiva pelo método minimamente invasivo com gancho. Para isso, foram utilizadas 30 cadelas alocadas aleatoriamente em três grupos experimentais: Controle, Placebo e Reiki. Todos os animais receberam metadona como medicação pré-anestésica (MPA), meloxicam, propofol na indução anestésica e isofluorano na manutenção anestésica. Imediatamente após a OVH, os animais do Reiki foram submetidos a uma única sessão de Reiki, os animais do Placebo receberam uma simulação da terapia Reiki por um indivíduo não terapeuta e os animais do Controle não receberam nenhum tratamento. Os animais foram avaliados por meio da forma curta da escala de dor de Glasgow (CMPS-SF) e da escala visual analógica (EVA) antes da administração da MPA (M0) e 2h (M2), 4h (M4), 8h (M8), 12h (M12) e 24h (M24) após a MPA. Comparando-se os valores obtidos pela CMPS-SF, em M2, os valores do Reiki foram menores que do Placebo e, em M4, os valores do Reiki foram menores que do Controle e do Placebo. Observando-se os dados obtidos com a EVA, em M4 e M8, os valores do Reiki foram menores que do Controle e do Placebo. Foi administrada analgesia adicional (0,2 mg.kg-1 de morfina por via intramuscular) em três animais do Controle e em quatro animais do Placebo. Os animais do Reiki não necessitaram de analgesia adicional no período pós-operatório. Concluiu-se que a terapia Reiki contribuiu com a analgesia e o conforto pós-operatório de cadelas submetidas à OVH eletiva.(AU)

The need for opioid in the postoperative analgesia of dogs undergoing hemilaminectomy due to intervertebral disc extrusion / A necessidade de opioide na analgesia pós-operatória de cães submetidos à hemilaminectomia devido à extrusão do disco intervertebral

The aim of this study was to evaluate the postoperative analgesic effect of protocols with and without the opioid methadone in dogs with intervertebral disc extrusion undergoing decompressive surgery. Sixteen paraplegic dogs with preserved nociception underwent hemilaminectomy/disc fenestration and were randomly assigned to two groups. The analgesic protocol consisted of methadone, meloxicam and dipyrone in Group I (G1), and meloxicam and dipyrone in Group II (G2). The animals were blindly assessed by two observers, using the visual analogue scale (VAS) and the short-form Glasgow Composite Measure Pain Scale (CMPS-SF). Assessments occurred every 2 hours during first 24 hours post-surgery, and every 4 hours afterwards. There was no statistical difference among groups regarding pain scores or analgesic rescues. Both analgesic protocols provided analgesia in the initial 48 hours postoperatively, demonstrating that opioids are not necessary in the postoperative period of dogs undergoing hemilaminectomy and disc fenestration.(AU)

O objetivo deste estudo foi avaliar a analgesia pós-operatória de protocolos com e sem o opioide metadona em cães com extrusão de disco intervertebral submetidos à descompressão cirúrgica. Dezesseis cães paraplégicos com presença de nocicepção foram submetidos à hemilaminectomia/fenestração de disco e distribuídos aleatoriamente em dois grupos. No Grupo I (G1), o protocolo analgésico consistiu em metadona, meloxicam e dipirona e, no Grupo II (G2), por meloxicam e dipirona. Os pacientes foram avaliados de maneira cega por dois avaliadores, com base na escala visual analógica (EVA) e na escala simplificada composta de dor de Glasgow (CMPS-SF). As avaliações ocorreram a cada 2 horas durante as primeiras 24 horas de pós-operatório e, por mais 24 horas, a cada 4 horas. Não houve diferença estatística entre os grupos avaliados em relação à escores de dor e nem a necessidade de resgate analgésico. Ambos os protocolos promoveram analgesia nas 48 horas iniciais de pós-operatório, demonstrando não haver a necessidade do uso de opioide em cães submetidos à hemilaminectomia e fenestração de disco.(AU)