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Int J Gynaecol Obstet ; 8(2): 43-50, Mar. 1970.
Artigo em Inglês | MedCarib | ID: med-14657

RESUMO

Forty-seven patients with primary amenorrhea, oligomenorrhea, and secondary amenorrhea were investigated by chromosome examination, and laparotomy was performed in six. Thirty-six percent of patients with primary amenorrhea showed sex chromosomal abnormality, and two cases showed autosomal anomalities. We feel that undetected mosaicism was present in some of the sexual infantile patients with apparently normal complement; probably, several of this group have gonadal dysgenesis. No abnormality was detected in patients with virilization. However, we now believe that any patient without adrenal hyperplasia should have laparotomy and removal of abnormal gonadal tissue. Laparotomy and gonadal extirpation may be considered for patients with streak gonads without virilization. Patients with normal secondary sexual development deserve full and early investigation of the genital tract, as they may have congenital anomalities associated with normal ovaries (Summary)


Assuntos
Humanos , Adolescente , Adulto , Feminino , Amenorreia/genética , Citogenética , Sinais e Sintomas , Aberrações dos Cromossomos Sexuais , Hipogonadismo , Virilismo , Estatura , Índias Ocidentais
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