RESUMO
The course of 24 "J" -type diabetics attending the University College Hospital of the West Indies was reviewed. The "J" type is not a separate subgroup. So-called "J" -type cases are type-II cases in which the diabetes has been badly treated.(AU)
Assuntos
Humanos , Adulto , Pessoa de Meia-Idade , Masculino , Feminino , Diabetes Mellitus/classificação , Biópsia , Glucagon/administração & dosagem , Carbutamida/administração & dosagem , Insulina/farmacocinética , Diabetes Mellitus/diagnóstico , Cetoacidose Diabética , Jamaica , Diabetes Mellitus Tipo 1 , Diabetes Mellitus Tipo 2RESUMO
The case of a diabetic adult male who exhibited a number of serious toxic reactions to carbutamide administration is reported. The findings included thrombocytopenia, fever, lymphocytosis, generalized lymphadenopathy, exfoliative dermatitis, hepatitis and the development of a secondary anemia. Recovery followed administration of cortisone. Delayed "hypoglycemic" episodes were associated with adminstration of high dosage of the drug.(AU)
Assuntos
Humanos , Adulto , Masculino , Carbutamida/efeitos adversos , Diabetes Mellitus/complicações , Cortisona/administração & dosagem , Hemoglobinometria , Trombocitopenia , Febre , Linfocitose , Dermatite Esfoliativa , Anemia , Dieta para DiabéticosRESUMO
The oral treatment of eight diabetic patients with B.Z.55 (carbutamide) is reported. Two middle aged non-obese patients and one underweight patient responded satisfactorily and were discharged taking the drug. Two underweight Type II patients responded well to 8 and 10 g. per day. One "J" Type patient showed no response. Toxic effects were common with the high dosage employed. (AU)
