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1.
Biochem Genet ; 61(3): 945-962, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-36251226

RESUMO

The American horseshoe crab (Limulus polyphemus) is an economically and ecologically important species, which is currently categorized as endangered in Mexico. L. polyphemus, one of four extant horseshoe crab species that constitute the class Merostomata, is distributed along the Atlantic coastline of the USA from Alabama to Maine and has another population on the coastline of Campeche, Yucatan, and Quintana Roo in the Yucatan Peninsula, Mexico. In the present study, we evaluated the genetic diversity and genetic structure of four separated localities along the coast of the Yucatan peninsula (Champoton, CH; Isla Arena, IA; Rio Lagartos, RL; and Holbox Island, HI), using nine microsatellite-type molecular markers for this species. The aim of this study is to obtain a baseline of the current level of genetic diversity, which would allow the monitoring of important changes over time. Multilocus analyses revealed moderate levels of genetic diversity (He, 0.5230 to 0.6389) and genetic structure within the whole study area (FST 0.025). The population from RL showed limited gene flows, differing significantly from the other sampling sites. The genetic information obtained in this study can support the implementation of management and conservation programs for this species in Mexico.


Assuntos
Caranguejos Ferradura , Repetições de Microssatélites , Animais , Caranguejos Ferradura/genética , México , Variação Genética
2.
Sensors (Basel) ; 23(15)2023 Aug 07.
Artigo em Inglês | MEDLINE | ID: mdl-37571790

RESUMO

Reference evapotranspiration (ET0) is the first step in calculating crop irrigation demand, and numerous methods have been proposed to estimate this parameter. FAO-56 Penman-Monteith (PM) is the only standard method for defining and calculating ET0. However, it requires radiation, air temperature, atmospheric humidity, and wind speed data, limiting its application in regions where these data are unavailable; therefore, new alternatives are required. This study compared the accuracy of ET0 calculated with the Blaney-Criddle (BC) and Hargreaves-Samani (HS) methods versus PM using information from an automated weather station (AWS) and the NASA-POWER platform (NP) for different periods. The information collected corresponds to Module XII of the Lagunera Region Irrigation District 017, a semi-arid region in the North of Mexico. The HS method underestimated the reference evapotranspiration (ET0) by 5.5% compared to the PM method considering the total ET0 of the study period (26 February to 9 August 2021) and yielded the best fit in the different evaluation periods (daily, 5-day mean, and 5-day cumulative); the latter showed the best values of inferential parameters. The information about maximum and minimum temperatures from the NP platform was suitable for estimating ET0 using the HS equation. This data source is a suitable alternative, particularly in semi-arid regions with limited climatological data from weather stations.

3.
Artigo em Inglês | MEDLINE | ID: mdl-37702700

RESUMO

A complete screening was performed in a family after one of its members presented with a sudden cardiac death event. A genetical analysis revealed a mutation which led to a long QT syndrome.

4.
Proc Natl Acad Sci U S A ; 116(5): 1553-1558, 2019 01 29.
Artigo em Inglês | MEDLINE | ID: mdl-30642965

RESUMO

Educational attainment is one lever that can increase opportunity for economically disadvantaged families-especially in Science, Technology, Engineering, and Math (STEM). Unfortunately, students from lower-income backgrounds often perform poorly and fail high school STEM courses, which are a necessary step in pursuing fast-growing and lucrative STEM careers, graduating high school, and matriculating to college. We reasoned that, because high school STEM courses often use high-stakes tests to gauge performance, and such tests can be especially stressful for lower-income students, interventions that help students regulate their negative emotions during tests should reduce the achievement gap between higher- and lower-income students. In a large-scale (n = 1,175) field experiment conducted in ninth grade science classrooms, students were asked to complete a control exercise, or they were given the opportunity to complete an exercise to help them regulate their worries and reinterpret their anxious arousal before their tests. We found significant benefits of emotion regulation activities for lower-income students in terms of their science examination scores, science course passing rate, and students' attitudes toward examination stress, suggesting that students' emotions are one factor that impacts performance. For example, 39% of lower-income students failed the course in the control group compared with only 18% of students failing the course if they participated in the emotion regulation interventions-a reduction in course failure rate by half. Our work underscores the crucial importance of targeting students' emotions during impactful points in their academic trajectories for improving STEM preparedness and enhancing overall academic success.


Assuntos
Emoções/fisiologia , Pobreza/psicologia , Logro , Adolescente , Ansiedade/psicologia , Atitude , Avaliação Educacional/métodos , Engenharia , Feminino , Humanos , Masculino , Matemática , Instituições Acadêmicas , Ciência , Fatores Socioeconômicos , Estudantes , Tecnologia
5.
Cultur Divers Ethnic Minor Psychol ; 27(2): 256-268, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-33370136

RESUMO

OBJECTIVES: Navigating pathways of higher education means uncovering hidden "rules" about how to be successful in university systems that privilege dominant ways of knowing. To unpack these rules, universities have attempted a range of approaches from enrolling students in semester-long courses focused on the transition to college to more cost-effective psychological interventions that use stories to highlight pathways for navigating the transition. These cost-effective approaches are of increased interest to universities and effective in promoting student outcomes. Yet, their effects have mostly been examined in predominantly White institutions leaving open the question of how to tailor these interventions in less-resourced institutions serving a more diverse student body. We examined the effect of making these hidden resources known in concrete ways and of contextualizing these resources with student stories through a scalable online video-based assignment. METHOD: Across 2 large-scale experiments at a minority serving institution, participants watched either resource videos only or resource videos coupled with students' stories. RESULTS: Compared to a no-treatment control group, we found that first-generation-to-college students benefited from receiving both types of resource information. Continuing-generation-to-college students benefited the most when resources were coupled with student stories. CONCLUSIONS: We speculate that first-generation students at minority serving institutions have concrete concerns that need to be addressed alongside identity and social belonging needs. (PsycInfo Database Record (c) 2021 APA, all rights reserved).


Assuntos
Estudantes , Universidades , Logro , Humanos , Grupos Minoritários
6.
Int J Psychol ; 53 Suppl 2: 81-90, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-29926910

RESUMO

Around the world, people migrate from poorer countries with less educational opportunity to richer ones with greater educational opportunity. In this journey, they bring their family obligation values into societies that value individual achievement. This process can create home-school cultural value conflict-conflict between family and academic obligations-for the children of Latina/o immigrants who attend universities in the United States. We hypothesised that this conflict causes cognitive disruption. One-hundred sixty-one Latina/o first-generation university students (called college students in the United States) were randomly assigned to one of four experimental prompts; thereafter, the students engaged in an attentional control task (i.e., the Stroop test). For Latina/o students living close to home, prompting a home-school cultural value conflict was more deleterious to attentional control than the other conditions. In addition, across all Latina/o students, a comparison of performance before and after President Trump's election and inauguration showed that prompting family obligation (without mention of conflict) led to a significantly greater loss of attentional control after Trump was elected and inaugurated, compared with before Trump. We hypothesise that this effect resulted from Trump's threats and actions to deport undocumented Latina/o immigrants, thus making fear about the fate of family members more salient and cognitively disruptive.


Assuntos
Atenção/fisiologia , Cultura , Hispânico ou Latino/psicologia , Estudantes/psicologia , Criança , Etnopsicologia , Conflito Familiar , Feminino , Humanos , Masculino , Políticas , Distribuição Aleatória , Estados Unidos
7.
Rev Invest Clin ; 69(6): 314-318, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-29265116

RESUMO

BACKGROUND: Acute pancreatitis (AP), a disease that commonly requires in-hospital treatment, has been associated with a high incidence of abnormal cardiovascular findings (ACFs). We conducted a prospective study to explore the association of these findings with severity of the disease. METHODS: Adult patients with AP diagnosis were prospectively enrolled in an observational study during an 8-month period in a tertiary care center. AP and its severity were defined according to the Revised Atlanta Classification of AP. Subjects were submitted to electrocardiographic, echocardiographic, and serologic testing during the acute period and a 3-month follow-up. The incidence of ACF was compared between two groups: (1) Mild and (2) moderate/severe cases. RESULTS: Twenty-seven patients (mean age 48 ± 17 years) with AP were enrolled; 15 (55%) had mild and 12 (45%) had moderate/severe AP. During the acute episode, 67% had increased pro-brain natriuretic peptide levels; 52% had abnormal electrocardiographic findings; 48% had abnormal echocardiographic findings; and 18% had increased troponin I levels. There was no significant difference in the incidence of ACF between mild and moderate/severe groups. Nineteen patients (70%) had repeated follow-up testing, and most of the initial ACF did not persist. CONCLUSION: ACFs occur in an important proportion of patients during AP episodes. Future research should continue to focus in the association of ACFs and the severity of the disease.


Assuntos
Doenças Cardiovasculares/epidemiologia , Peptídeo Natriurético Encefálico/metabolismo , Pancreatite/fisiopatologia , Fragmentos de Peptídeos/metabolismo , Doença Aguda , Adulto , Idoso , Doenças Cardiovasculares/etiologia , Doenças Cardiovasculares/fisiopatologia , Ecocardiografia , Eletrocardiografia , Feminino , Seguimentos , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Pancreatite/complicações , Estudos Prospectivos , Índice de Gravidade de Doença , Centros de Atenção Terciária
8.
Hum Biol ; 88(2): 136-167, 2016 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-28162001

RESUMO

Maya civilization developed in Mesoamerica and encompassed the Yucatan Peninsula, Guatemala, Belize, part of the Mexican states of Tabasco and Chiapas, and the western parts of Honduras and El Salvador. This civilization persisted approximately 3,000 years and was one of the most advanced of its time, possessing the only known full writing system at the time, as well as art, sophisticated architecture, and mathematical and astronomical systems. This civilization reached the apex of its power and influence during the Preclassic period, from 2000 BCE to 250 CE. Genetic variation in the pre-Hispanic Mayas from archaeological sites in the Mexican states of Yucatan, Chiapas, Quintana Roo, and Tabasco and their relationship with the contemporary communities in these regions have not been previously studied. Consequently, the principal aim of this study was to determine mitochondrial DNA (mtDNA) variation in the pre-Hispanic Maya population and to assess the relationship of these individuals with contemporary Mesoamerican Maya and populations from Asia, Beringia, and North, Central, and South America. Our results revealed interactions and gene flow between populations in the different archaeological sites assessed in this study. The mtDNA haplogroup frequency in the pre-Hispanic Maya population (60.53%, 34.21%, and 5.26% for haplogroups A, C, and D, respectively) was similar to that of most Mexican and Guatemalan Maya populations, with haplogroup A exhibiting the highest frequency. Haplogroup B most likely arrived independently and mixed with populations carrying haplogroups A and C based on its absence in the pre-Hispanic Mexican Maya populations and low frequencies in most Mexican and Guatemalan Maya populations, although this also may be due to drift. Maya and Ciboneys sharing haplotype H10 belonged to haplogroup C1 and haplotype H4 of haplogroup D, suggesting shared regional haplotypes. This may indicate a shared genetic ancestry, suggesting more regional interaction between populations in the circum-Caribbean region than previously demonstrated. Haplotype sharing between the pre-Hispanic Maya and the indigenous populations from Asia, the Aleutian Islands, and North, Central, and South America provides evidence for gene flow from the ancestral Amerindian population of the pre-Hispanic Maya to Central and South America.


Assuntos
DNA Mitocondrial/genética , Variação Genética , Indígenas Centro-Americanos/genética , Arqueologia , Evolução Molecular , Fluxo Gênico , Genética Populacional , Haplótipos , Humanos , Filogeografia
9.
J Exp Child Psychol ; 141: 83-100, 2016 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-26342473

RESUMO

Even at young ages, children self-report experiencing math anxiety, which negatively relates to their math achievement. Leveraging a large dataset of first and second grade students' math achievement scores, math problem solving strategies, and math attitudes, we explored the possibility that children's math anxiety (i.e., a fear or apprehension about math) negatively relates to their use of more advanced problem solving strategies, which in turn relates to their math achievement. Our results confirm our hypothesis and, moreover, demonstrate that the relation between math anxiety and math problem solving strategies is strongest in children with the highest working memory capacity. Ironically, children who have the highest cognitive capacity avoid using advanced problem solving strategies when they are high in math anxiety and, as a result, underperform in math compared with their lower working memory peers.


Assuntos
Logro , Ansiedade/psicologia , Matemática , Resolução de Problemas , Criança , Pré-Escolar , Medo , Feminino , Humanos , Masculino , Memória de Curto Prazo , Instituições Acadêmicas , Autorrelato
10.
Psychol Sci ; 26(9): 1480-8, 2015 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-26253552

RESUMO

A large field study of children in first and second grade explored how parents' anxiety about math relates to their children's math achievement. The goal of the study was to better understand why some students perform worse in math than others. We tested whether parents' math anxiety predicts their children's math achievement across the school year. We found that when parents are more math anxious, their children learn significantly less math over the school year and have more math anxiety by the school year's end-but only if math-anxious parents report providing frequent help with math homework. Notably, when parents reported helping with math homework less often, children's math achievement and attitudes were not related to parents' math anxiety. Parents' math anxiety did not predict children's reading achievement, which suggests that the effects of parents' math anxiety are specific to children's math achievement. These findings provide evidence of a mechanism for intergenerational transmission of low math achievement and high math anxiety.


Assuntos
Logro , Ansiedade/psicologia , Matemática , Relações Pais-Filho , Pais/psicologia , Estudantes/psicologia , Criança , Feminino , Humanos , Masculino , Leitura , Instituições Acadêmicas
11.
Sensors (Basel) ; 14(11): 20645-66, 2014 Oct 31.
Artigo em Inglês | MEDLINE | ID: mdl-25365462

RESUMO

In this article, a toolbox based on a monitoring and control interface (MCI) is presented and applied in a heat exchanger. The MCI was programed in order to realize sensor fault detection and isolation and fault tolerance using virtual sensors. The virtual sensors were designed from model-based high-gain observers. To develop the control task, different kinds of control laws were included in the monitoring and control interface. These control laws are PID, MPC and a non-linear model-based control law. The MCI helps to maintain the heat exchanger under operation, even if a temperature outlet sensor fault occurs; in the case of outlet temperature sensor failure, the MCI will display an alarm. The monitoring and control interface is used as a practical tool to support electronic engineering students with heat transfer and control concepts to be applied in a double-pipe heat exchanger pilot plant. The method aims to teach the students through the observation and manipulation of the main variables of the process and by the interaction with the monitoring and control interface (MCI) developed in LabVIEW©. The MCI provides the electronic engineering students with the knowledge of heat exchanger behavior, since the interface is provided with a thermodynamic model that approximates the temperatures and the physical properties of the fluid (density and heat capacity). An advantage of the interface is the easy manipulation of the actuator for an automatic or manual operation. Another advantage of the monitoring and control interface is that all algorithms can be manipulated and modified by the users.

12.
Sensors (Basel) ; 14(5): 7580-601, 2014 Apr 25.
Artigo em Inglês | MEDLINE | ID: mdl-24776933

RESUMO

Here; we have described and tested a microarray based-method for the screening of dengue virus (DENV) serotypes. This DNA microarray assay is specific and sensitive and can detect dual infections with two dengue virus serotypes and single-serotype infections. Other methodologies may underestimate samples containing more than one serotype. This technology can be used to discriminate between the four DENV serotypes. Single-stranded DNA targets were covalently attached to glass slides and hybridised with specific labelled probes. DENV isolates and dengue samples were used to evaluate microarray performance. Our results demonstrate that the probes hybridized specifically to DENV serotypes; with no detection of unspecific signals. This finding provides evidence that specific probes can effectively identify single and double infections in DENV samples.


Assuntos
Técnicas Biossensoriais/instrumentação , DNA Viral/genética , Vírus da Dengue/genética , Vírus da Dengue/isolamento & purificação , Dengue/diagnóstico , Dengue/virologia , Análise de Sequência com Séries de Oligonucleotídeos/instrumentação , Vírus da Dengue/classificação , Desenho de Equipamento , Análise de Falha de Equipamento , Humanos , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Sorogrupo
13.
J Intell ; 12(3)2024 Mar 04.
Artigo em Inglês | MEDLINE | ID: mdl-38535164

RESUMO

Women reliably perform worse than men on measures of spatial ability, particularly those involving mental rotation. At the same time, females also report higher levels of spatial anxiety than males. What remains unclear, however, is whether and in what ways gender differences in these cognitive and affective aspects of spatial processing may be interrelated. Here, we tested for robust gender differences across six different datasets in spatial ability and spatial anxiety (N = 1257, 830 females). Further, we tested for bidirectional mediation effects. We identified indirect relations between gender and spatial skills through spatial anxiety, as well as between gender and spatial anxiety through spatial skills. In the gender → spatial anxiety → spatial ability direction, spatial anxiety explained an average of 22.4% of gender differences in spatial ability. In the gender → spatial ability → spatial anxiety direction, spatial ability explained an average of 25.9% of gender differences in spatial anxiety. Broadly, these results support a strong relation between cognitive and affective factors when explaining gender differences in the spatial domain. However, the nature of this relation may be more complex than has been assumed in previous literature. On a practical level, the results of this study caution the development of interventions to address gender differences in spatial processing which focus primarily on either spatial anxiety or spatial ability until such further research can be conducted. Our results also speak to the need for future longitudinal work to determine the precise mechanisms linking cognitive and affective factors in spatial processing.

14.
Proc Natl Acad Sci U S A ; 107(5): 1860-3, 2010 Feb 02.
Artigo em Inglês | MEDLINE | ID: mdl-20133834

RESUMO

People's fear and anxiety about doing math--over and above actual math ability--can be an impediment to their math achievement. We show that when the math-anxious individuals are female elementary school teachers, their math anxiety carries negative consequences for the math achievement of their female students. Early elementary school teachers in the United States are almost exclusively female (>90%), and we provide evidence that these female teachers' anxieties relate to girls' math achievement via girls' beliefs about who is good at math. First- and second-grade female teachers completed measures of math anxiety. The math achievement of the students in these teachers' classrooms was also assessed. There was no relation between a teacher's math anxiety and her students' math achievement at the beginning of the school year. By the school year's end, however, the more anxious teachers were about math, the more likely girls (but not boys) were to endorse the commonly held stereotype that "boys are good at math, and girls are good at reading" and the lower these girls' math achievement. Indeed, by the end of the school year, girls who endorsed this stereotype had significantly worse math achievement than girls who did not and than boys overall. In early elementary school, where the teachers are almost all female, teachers' math anxiety carries consequences for girls' math achievement by influencing girls' beliefs about who is good at math.


Assuntos
Ansiedade , Docentes , Matemática/educação , Estudantes/psicologia , Criança , Medo , Feminino , Humanos , Masculino , Autoavaliação (Psicologia) , Caracteres Sexuais , Estados Unidos
15.
J Am Mosq Control Assoc ; 29(1): 1-18, 2013 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-23687850

RESUMO

Patterns of gene flow vary greatly among Aedes aegypti populations throughout Mexico. The populations are panmictic along the Pacific coast, isolated by distance in northeast Mexico, and exhibit moderate gene flow across the Yucatan peninsula. Nine Ae. aegypti collections from 6 cities in Oaxaca, Mexico, were taken to examine the local patterns of gene flow. Genetic variation was examined in a 387-bp region of the nicotinamide adenine dinucleotide dehydrogenase subunit 4 mitochondrial gene (ND4) using single-strand conformation polymorphism analysis, and 3 haplotypes were detected. Cluster analysis on the linearized FST genetic distances failed to group collections in geographic proximity. Regression analysis of linear or road distances on linearized F(ST) indicated that proximal collections were as diverse as distant collections across an approximately 800-km range. The geographical distribution of the Mexican mosquito haplotype frequencies was determined for the ND4 sequences from 524 individuals from Oaxaca (this study) and 2,043 individuals from our previous studies. Herein, we report on yet another pattern dominated by genetic drift among 9 Ae. aegypti collections from 6 cities in Oaxaca, Mexico, and compare it to those reported in other regions of Mexico. Molecular analysis of variance showed that there was as much genetic variation among collections 4 km apart as there was among all collections. The numbers of haplotypes and the amount of genetic diversity among the collections from Oaxaca were much lower than detected in previous studies in other regions of Mexico and may reflect the effects of control efforts or adaptations to the altitudinal limits (1,500 m) of the species in Mexico. The geographical distribution of mosquito haplotypes in Mexico is also reported. Furthermore, based on the distribution of the mosquito haplotypes in America, we suggest that mosquito dispersion is very efficient, most likely due to commercial transportation.


Assuntos
Aedes/genética , DNA Mitocondrial/genética , Fluxo Gênico , Variação Genética , Animais , Análise por Conglomerados , Geografia , Haplótipos , América Latina , México , Filogenia
16.
Artigo em Inglês | MEDLINE | ID: mdl-24007438

RESUMO

Previous studies, based on limited data, found elevated levels of mercury in carp in Lake Chapala, Mexico. The extent of mercury contamination in carp throughout the Lake has not been determined. In order to obtain reliable information about total mercury concentration in carp (Cyprinus carpio), 262 fish from 27 sites (approximately 10 fish per site) throughout the lake were analyzed. Results were expressed as the mean and median of the results at each site. Only one of the samples exceeded Mexican National Standard (1.0 ppm) for mercury in fish flesh. We discuss these results in comparison to World Health Organization (WHO), US Food and Drug Administration (FDA) and US Environmental Protection Agency (US EPA) criteria; many of our samples exceed these criteria based on Tolerable Daily Intake (TDI) or Reference Dose (RfD). ANOVA of four groups of mercury results clustered by distance from the Lerma showed statistically significant differences (P = 0.0071) between the group closest to, versus farthest from, the Lerma River.


Assuntos
Carpas/metabolismo , Exposição Ambiental , Contaminação de Alimentos/análise , Mercúrio/metabolismo , Poluentes Químicos da Água/metabolismo , Animais , Monitoramento Ambiental , Feminino , Humanos , Lagos , Masculino , México , Espectrofotometria Atômica
17.
Rev Med Inst Mex Seguro Soc ; 61(Suppl 2): S193-S199, 2023 Sep 18.
Artigo em Espanhol | MEDLINE | ID: mdl-38011687

RESUMO

Background: The anterior cervical discectomy and fusion (ACDF) is the gold standard in the treatment of cervical compression pathology and the titanium cage for fusion represents the most used procedure at an institutional level. A technique using fibular autograft has been described, with good results, lower morbidity and lower cost. Objective: To compare the rate of fusion, subsidence and functional clinical results after discectomy with titanium cage and fibular autograft. Material and methods: A clinical trial with follow-up at 3 and 6 months was carried out in patients diagnosed with cervical spondylosis, candidates for ACDF. 2 groups were formed: fibular autograft and titanium cage. Pre and post functional evaluation using the cervical disability score was made, as well as radiographic fusion and subsidence evaluation. Descriptive statistics, Fisher's exact test, t-test and ANOVA were obtained, establishing p < 0.05. Results: A sample of 20 patients with an average age of 56 years was obtained, finding a fusion rate of 90% for fibular autograft and 30% for titanium (p = 0.02) at 3 months. 10% of patients with fibular autograft presented subsidence and 70% with titanium cage at 3 and 6 months (p = 0.02). In the functional results was not found difference between both procedures (p = 0.874). Conclusions: The use of autologous fibular graft offers a better rate of fusion and subsidence compared to the titanium cage, as well as similar functional results at 3 months of follow-up. It represents an excellent treatment option for cervical spondylosis.


Introducción: la disectomía cervical anterior y fusión (ACDF) es el estándar de oro en el tratamiento de la patología compresiva cervical. La caja de titanio para artrodesis es el procedimiento más usado a nivel institucional. Se ha descrito una técnica con autoinjerto de peroné, con buenos resultados, menor morbilidad y menor costo. Objetivo: comparar la tasa de fusión, subsidencia y resultados clínicos funcionales posteriores a disectomía con caja de titanio y autoinjerto de peroné. Material y métodos: ensayo clínico con seguimiento a tres y seis meses en pacientes con diagnóstico de espondilosis cervical, candidatos a ACDF. Se formaron dos grupos: autoinjerto de peroné y caja de titanio. Se hizo evaluación funcional antes y después mediante la escala de discapacidad cervical, y evaluación de fusión y subsidencia radiográficas. Se usó estadística descriptiva, prueba exacta de Fisher, prueba t y ANOVA, estableciendo una p < 0.05. Resultados: se obtuvo una muestra de 20 pacientes con promedio de 56 años; hubo una tasa de fusión del 90% para autoinjerto de peroné y 30% para titanio (p = 0.02) a los tres meses. De los pacientes con autoinjerto de peroné, 10% presentaron subsidencia y un 70% con caja de titanio a los tres y seis meses (p = 0.02). No se encontró diferencia en los resultados funcionales a tres y seis meses de ambos procedimientos. Conclusiones: el uso de injerto autólogo de peroné ofrece mejor tasa de fusión y subsidencia en comparación con la caja de titanio, así como resultados funcionales similares a los tres meses. Es una excelente opción para tratar la espondilosis cervical.


Assuntos
Vértebras Cervicais , Fusão Vertebral , Espondilose , Titânio , Transplante Autólogo , Humanos , Pessoa de Meia-Idade , Autoenxertos , Vértebras Cervicais/cirurgia , Fíbula , Estudos Retrospectivos , Fusão Vertebral/métodos , Espondilose/cirurgia , Espondilose/tratamento farmacológico , Titânio/uso terapêutico , Resultado do Tratamento , Seguimentos
18.
Arch Med Res ; 54(2): 113-123, 2023 02.
Artigo em Inglês | MEDLINE | ID: mdl-36792418

RESUMO

BACKGROUND: According to the International Diabetes Federation, Mexico is seventh place in the prevalence of type 2 diabetes (T2D) worldwide. Mitochondrial DNA variant association studies in multifactorial diseases like T2D are scarce in Mexican populations. AIM OF THE STUDY: The objective of this study was to analyze the association between 18 variants in the mtDNA control region and T2D and related metabolic traits in a Mexican mestizo population from Mexico City. METHODS: This study included 1001 participants divided into 477 cases with T2D and 524 healthy controls aged between 42 and 62 years and 18 mtDNA variants with frequencies >15%. RESULTS: Association analyses matched by age and sex showed differences in the distribution between cases and controls for variants m.315_316insC (p = 1.18 × 10-6), m.489T>C (p = 0.009), m.16362T>C (p = 0.001), and m.16519T>C (p = 0.004). The associations between T2D and variants m.315_316ins (OR = 6.13, CI = 3.42-10.97, p = 1.97 × 10-6), m.489T>C (OR = 1.45, CI = 1.00-2.11, p = 0.006), m.16362T>C (OR = 2.17, CI = 1.57-3.00, p = 0.001), and m.16519T>C (OR = 1.69, CI = 1.23-2.33, p = 0.006) were significant after performing logistic regression models adjusted for age, sex, and diastolic blood pressure. Metabolic traits in the control group through linear regressions, adjusted for age, sex and BMI, and corrected for multiple comparisons showed nominal association between glucose and variants m.263A>G (p <0.050), m.16183A>C (p <0.010), m.16189T>C (p <0.020), and m.16223C>T (p <0.024); triglycerides, and cholesterol and variant m.309_310insC (p <0.010 and p <0.050 respectively); urea, and creatinine, and variant m.315_316insC (p <0.007, and p <0.004 respectively); diastolic blood pressure and variants m.235A>G (p <0.016), m.263A>G (p <0.013), m.315_316insC (p <0.043), and m.16111C>T (p <0.022). CONCLUSION: These results demonstrate a strong association between variant m.315_316insC and T2D and a nominal association with T2D traits.


Assuntos
Diabetes Mellitus Tipo 2 , Genoma Mitocondrial , Humanos , Adulto , Pessoa de Meia-Idade , Diabetes Mellitus Tipo 2/genética , México/epidemiologia , Colesterol , DNA Mitocondrial/genética , Polimorfismo de Nucleotídeo Único
19.
Gac Med Mex ; 148(2): 125-9, 2012.
Artigo em Espanhol | MEDLINE | ID: mdl-22622311

RESUMO

A patient with resistant hypertension successfully treated with sympathetic renal denervation (SRD) is reported. This novel therapy is based on the partial ablation of the renal nerves by applying radiofrequency to the luminal surface of the renal arteries using vascular catheterization techniques. This first case performed in Mexico has two particular features: (i) an electrophysiology ablation catheter was employed due to the unavailability of the system specifically designed for SDR, and (ii) under current denervation protocols, the anatomical complexity of the targeted renal arteries would have excluded our patient from this procedure and thus deprived her of the benefit provided.


Assuntos
Hipertensão/cirurgia , Rim/inervação , Rim/cirurgia , Simpatectomia , Adulto , Feminino , Humanos
20.
J Phys Condens Matter ; 34(34)2022 Jun 24.
Artigo em Inglês | MEDLINE | ID: mdl-35705073

RESUMO

Relativistic calculations of the structural and spectral properties of the PbO molecule can provide fundamental information about the importance of a proper treatment of angular momentum coupling among electrons in order to achieve accurate computational results for spectral properties. Specifically, the nature of these couplings in PbO is expected to be intermediate between theLS- andjj-coupling limits because of its light/heavy element composition. This article reports potential energy curves, transition energies, electric dipole transition moments, permanent dipole moments and spectroscopic constants of PbO calculated using a multireference single plus double excitations spin-orbit configuration interaction approach in the context of relativistic effective core potentials and their concomitant spin-orbit coupling operators. The calculated results are in general agreement with both available experimental results as well as earlier calculations. New values for properties of excited states are also reported. It is noteworthy that certain properties show larger deviations from previous calculations. These deviations are attributed to direct and indirect relativistic effects resulting from diatomic electron-electron angular momentum coupling effects, which are included consistently in the calculations reported herein.

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