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Annals of Pediatric Endocrinology & Metabolism ; : 68-70, 2019.
Article in English | WPRIM | ID: wpr-762586

ABSTRACT

Congenital rubella infection is a transplacental infection that can cause intrauterine growth retardation, cataracts, patent ductus arteriosus, hearing loss, microcephaly, thrombocytopenia, and severe fetal injury. It has been shown that type 1 diabetes mellitus develops in 12%–20% of patients with congenital rubella infection, and disorders in the oral glucose tolerance test is observed in 40% of patients. No biochemical or serological markers exist which could indicate that type 1 diabetes was caused by a congenital rubella infection. We report a 13-year-old male patient who was admitted to our hospital with complaints of new-onset polyuria, polydipsia, urination, and weight loss. In addition, he was found to have neurosensory hearing loss, patent ductus arteriosus, and microcephaly. Immunemediated type 1 diabetes mellitus was considered due to the fact that the autoantibodies of diabetes mellitus were positive.


Subject(s)
Adolescent , Humans , Male , Autoantibodies , Cataract , Diabetes Mellitus , Diabetes Mellitus, Type 1 , Ductus Arteriosus, Patent , Fetal Growth Retardation , Glucose Tolerance Test , Hearing Loss , Microcephaly , Polydipsia , Polyuria , Rubella , Thrombocytopenia , Urination , Weight Loss
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