ABSTRACT
<p><b>OBJECTIVE</b>To observe the curative effect of Qingjin Runfei Decoction (QRD) combined with hormone and antibiotic in treating radiation pneumonia (RP).</p><p><b>METHODS</b>Patients were randomly assigned to two groups, the control group (51 cases) treated with hormone and antibiotic and the treated group (53 cases) with the above therapy plus QRD. The curative effects on RP, quality of life (QOL), chest radiography and TCM symptoms were observed.</p><p><b>RESULTS</b>The curative effects on the above items in the treated group were all significantly better than those in the control group (P < 0.05).</p><p><b>CONCLUSION</b>QRD could enhance the effects of hormone and antibiotic in treating RP, as well as improve QOL of the patients.</p>
Subject(s)
Adult , Aged , Female , Humans , Male , Middle Aged , Anti-Bacterial Agents , Therapeutic Uses , Breast Neoplasms , Radiotherapy , Carcinoma, Non-Small-Cell Lung , Radiotherapy , Drug Therapy, Combination , Drugs, Chinese Herbal , Therapeutic Uses , Glucocorticoids , Therapeutic Uses , Lung Neoplasms , Radiotherapy , Medicine, Chinese Traditional , Phytotherapy , Prednisone , Therapeutic Uses , Quality of Life , Radiation Pneumonitis , Drug Therapy , PathologyABSTRACT
<p><b>OBJECTIVE</b>To observe the toxicity-attenuation effect of Yiguan Decoction (YGD) in treatment of non-small cell lung cancer (NSCLC) with NP protocol of chemotherapy.</p><p><b>METHODS</b>Ninety-two NSCLC patients were randomly assigned to two groups equally, the control group given only NP protocol of chemotherapy and the treated group given the same protocol of chemotherapy plus YGD. Hepatic function, T-cell subgroup and NK cell were examined, and quality of life (QOL) was evaluated with scoring by Karnofsky performance status (KPS), Quality of Life Questionnaire-Core30 (EORTC QLQ-C30) and Special Scale for lung cancer (EORTC LC13) issued by European Organization for Research and Treatment of Cancer.</p><p><b>RESULTS</b>The effects on all the above-mentioned indexes in the treated group were better than those in the control group after 42 days of treatment (P <0.05).</p><p><b>CONCLUSION</b>YGD could not only reduce the side and toxic effects caused by NP protocol of chemotherapy in NSCLC patients but also improve their QOL.</p>