1.
Rev. Soc. Bras. Med. Trop
; 55: e0728B-2022, 2022.
Article
in English
|
LILACS-Express
| LILACS
| ID: biblio-1407002
2.
Rev. Soc. Bras. Med. Trop
; 54: e0728-2020, 2021. tab, graf
Article
in English
| LILACS
| ID: biblio-1155535
ABSTRACT
Abstract INTRODUCTION: Mycobacterium tuberculosis (MTB) is a causative agent of tuberculosis (TB) that causes death worldwide. METHODS: MTB was subjected to phenotypic drug-susceptibility tests (DST), and drug-resistant genes were sequenced. RESULTS: Previously treated patients were more likely to have positive smear results and exhibit drug resistance. New patients were more likely to be mono SM-resistant and less likely to be INH- and RIF-resistant. The most common mutations were katG (S315T), rpoB (S450L), rpsL (K43R), and embB (M306V). CONCLUSIONS: The proportion of mono-SM-resistant TB among new patients was higher.