Neumoencéfalo como complicación de bloqueo regional epidural por radiculopatía lumbosacra / Pneumocephalus as a Complication of Regional Epidural Block Due to Lumbosacral Radiculopathy

Introducción: El neumoencéfalo (sinonimia: aerocele o neumatocele intracerebral), se define como la presencia de gas dentro de cualquiera de los compartimentos intracraneales (intraventricular, intraparenquimatosa, subaracnoidea, subdural y epidural). Objetivo: Describir los hallazgos clínicos, estudios complementarios, conducta terapéutica y evolución de un caso con neumoencéfalo como complicación de bloqueo regional epidural por radiculopatía lumbosacra. Presentación de caso: Se presentó un paciente masculino de 57 años de edad que comenzó con un cuadro súbito de desorientación, excitabilidad psicomotriz y convulsiones tónico-clónicas, a partir de una inyección epidural de metilprednisolona como método analgésico. Conclusiones: El caso presentado exhibió manifestaciones neurológicas inespecíficas, la aparición súbita posterior al proceder invasivo hizo sospechar en un evento neurológico agudo o fenómeno tromboembólico. Los estudios complementarios como la tomografía axial computarizada craneal simple, permitió su diagnóstico para tener una conducta consecuente. El manejo conservador del neumoencéfalo como complicación del uso de anestesia epidural, constituyó una conducta terapéutica eficaz y repercutió en la satisfactoria evolución del paciente(AU)

Introduction: Pneumocephalus (synonym: aerocele or intracerebral pneumatocele), is defined as the presence of gas within any of the intracranial compartments (intraventricular, intraparenchymal, subarachnoid, subdural and epidural). Objective: To describe the clinical findings, complementary studies, therapeutic conduct and evolution of a case with pneumocephalus as a complication of regional epidural block due to lumbosacral radiculopathy Case presentation: A 57-year-old male patient was presented who began with a sudden episode of disorientation, psychomotor excitability and tonic-clonic seizures, following an epidural injection of methylprednisolone as an analgesic method. Conclusions: The case presented exhibited non-specific neurological manifestations, the sudden appearance after the invasive procedure raised suspicion of an acute neurological event or thromboembolic phenomenon. Complementary studies such as simple cranial computed axial tomography, allowed its diagnosis to have a consistent conduct. The conservative management of pneumocephalus as a complication of the use of epidural anesthesia constituted an effective therapeutic approach and had an impact on the patient's satisfactory evolution(AU)

Síndrome de Mounier-Kuhn / Mounier-Kuhn Syndrome

El síndrome de Mounier-Kuhn o traqueobroncomegalia constituye una rara entidad clínica y radiológica caracterizada por una dilatación de la tráquea y los bronquios principales. Puede asociarse con estructuras saculares en las membranas intercartilaginosas (diverticulosis traqueal), bronquiectasias e infecciones respiratorias a repetición. Las formas de presentación clínica son variables. Tiene una prevalencia entre el 1-4,5 por ciento de la población y se presenta, mayoritariamente, en hombres con un amplio rango etario que oscila entre los 20 y 50 años de edad. Se presenta el caso de un paciente masculino de 77 años con cuadros de infecciones respiratorias bajas a repetición desde la juventud. Luego de realizarle estudios de imagen y broncoscopia, se llegó al diagnóstico de síndrome de Mounier-Kunh. Recibió tratamiento antibiótico inmediatamente y su evolución fue de manera satisfactoria(AU)

Mounier-Kuhn syndrome or tracheobroncomegaly is a rare clinical and radiological entity characterized by dilatation of the trachea and the main bronchi. It can be associated with saccular structures in the intercartilaginous membranes (tracheal diverticulosis), bronchiectasis, and recurrent respiratory infections. The forms of clinical presentation vary. It has a prevalence between 1-4.5 percent of the population and it occurs mainly in men, widely ranging ages between 20 and 50 years of age. We report the case of a 77-year-old male patient with recurrent lower respiratory infections since his youth. After performing imaging studies and bronchoscopy, he could be diagnosed with Mounier-Kunh syndrome. He immediately underwent antibiotic treatment and his evolution was satisfactory(AU)

Application value of magnetic resonance hydrography of the inner ear in cochlear implantation

SUMMARY OBJECTIVE This study aims to investigate the application value of magnetic resonance (MR) hydrography of the inner ear in cochlear implantation. METHODS 146 patients were enrolled. MR hydrography and spiral CT examinations for the intracranial auditory canal were performed before surgery, and all imaging results were statistically analyzed in order to explore the application value of MR hydrography of the inner ear in cochlear implantation. RESULTS 146 patients (292 ears) were examined. Among these patients, 13 were diagnosed with abnormal vestibular aqueducts (20 ears) by MR hydrography, while five were diagnosed with this disease by CT; 15 patients were diagnosed with inner ear malformation (19 ears) by MR hydrography, while 11 were diagnosed by CT (four were misdiagnosed); five patients were diagnosed with internal acoustic canal stenosis (eight ears) by MR hydrography, while two were diagnosed by CT (three were misdiagnosed); and four patients were diagnosed with cochlear fibrosis (five ears) by MR hydrography, while four were diagnosed by CT (four ears). The correct rate of diagnosis was 77.40% (113/146) based on CT, while the rate was 93.84% (137/146) based on MR hydrography. CONCLUSIONS MR hydrography imaging technique can be applied to the preoperative evaluation of cochlear implantation, providing accurate and reliable anatomic information on the inner membranous labyrinth and nerves in the internal acoustic canal and an accurate basis for the diagnosis of cochlear fibrosis and nerve development. This has a guiding significance for the selection of treatment schemes.

RESUMO OBJETIVO Este estudo visa investigar o valor da aplicação da hidrografia por ressonância magnética (RM) do ouvido interno no implante coclear. MÉTODOS Cento e quarenta e seis pacientes foram inscritos. Os exames da hidrografia por RM e do CT espiral para o canal auditivo intracraniano foram executados antes da cirurgia, e todos os resultados da imagem foram analisados estatisticamente, a fim de explorar o valor da aplicação da hidrografia por RM do ouvido interno no implante coclear. RESULTADOS Centro e quarenta e seis pacientes (292 ouvidos) foram examinados. Dentre esses pacientes, 13 foram diagnosticados com aquedutos vestibulares anormais (20 ouvidos) pela hidrografia por RM, enquanto cinco pacientes foram diagnosticados com esta doença pelo CT; 15 pacientes foram diagnosticados com malformação do ouvido interno (19 ouvidos) pela hidrografia por RM, enquanto 11 pacientes foram diagnosticados por CT (quatro foram diagnosticados erroneamente); cinco pacientes foram diagnosticados com estenose de canal acústico interno (oito ouvidos) pela hidrografia por RM, enquanto dois pacientes foram diagnosticados por CT (três foram diagnosticados erroneamente); e quatro pacientes foram diagnosticados com fibrose coclear (cinco ouvidos) pela hidrografia por RM, enquanto quatro foram diagnosticados por CT (quatro ouvidos). A taxa correta de diagnóstico foi de 77,40% (113/146) com base no CT, enquanto a taxa foi de 93,84% (137/146) com base na hidrografia por RM. CONCLUSÕES A técnica de imagem da hidrografia por RM pode ser aplicada à avaliação pré-operatória do implante coclear, que pode fornecer informações anatômicas precisas e confiáveis sobre o labirinto membranoso interno e os nervos no canal acústico interno, além de uma base exata para o diagnóstico da fibrose coclear e do desenvolvimento do nervo. Isso tem um significado orientador para a seleção de esquemas de tratamento.

Accidente cerebrovascular secundario a mixoma auricular izquierdo: una causa infrecuente de embolismo cerebral / Stroke due to a auricular myxoma: a infrequent cause of cerebral embolism

BACKGROUND: Atrial myxomas are very infrequent primary bening cardiac neoplasms, being considered a rare but highly fatal cause of cerebral embolism. Objectives: We describe the case of an ischemic stroke (CVA) with hemorrhagic conversion secondary to atrila myxoma as an embolic source, and its subsequent early surgical resolution. CLINICAL CASE: A 63-year-old male has a clinical episode compatible with ischemic stroke, receiving thrombolytics treatment with subsequent hemorrhagic conversion. Embolic source study show a mass compatible with cardiac myxoma in the left atrium, performing surgical resection via transeptal approach at 12 days of evolution, with repair of the interatrial defect with autologous pericardium patch. DISCUSSION: Atrial myxoma is a silent pathology and little diagnosed at its early stage, associated with events of systemic repercussion of high mortality and uncertain prognosis. Hemorrhagic cerebrovascular events constitute contraindication for anticoagulation prior to 21 days of evolution. In this case, due to the high embolic risk of myxoma, the inactivy of the bleeding was demonstrated by performing the surgery successfully on the twelfth day of evolution.

Ruptura del globo ocular / Rupture of the eyeball

Los traumatismos oculares representan la principal causa de pérdida de la agudeza visual en individuos jóvenes y se sitúa entre las causas de ceguera en el mundo. Pueden tener un efecto devastador sobre el globo ocular; es el tipo de traumatismo más severo en esta zona, con un pobre pronóstico visual para el paciente. Constituye un accidente grave, que en muchas ocasiones conlleva a la enucleación. Se presentan tres pacientes con rotura del globo ocular, con la conducta terapéutica, seguimiento y resultados visuales en cada caso, para mostrar a la comunidad médica, la complejidad y particularidades de este traumatismo(AU)

Ocular traumatisms represent the principal cause of loss of vision in young people and they are among the causes of blindness in the world. Trauma can result in a wide spectrum of tissue lesions of the globe and it can has devastating effect on the eyeball, since it is the most severe type of trauma in this area, with a poor visual prognosis for the patient. It is a serious accident, which often leads to nucleation as result of a bruised intense trauma. This is the report of three patients with rupture of the ocular globe with the therapeutic behavior, follow-up and visual results in each case, to show the medical community, the complexity and particularities of this traumatism(AU)

Guía de práctica clínica para el diagnóstico y tratamiento de la etapa aguda del ataque cerebrovascular isquémico / Clinical practice guideline for the diagnosis and treatment of the acute stage of ischemic stroke

El GEG-Local consideró que es muy importante tener una herramienta disponible para la detección prehospitalaria de pacientes con ACVi de vaso grande, en especial para las áreas donde se dispone de ambas opciones de referencia: centro especializado para el manejo de ACVi con trombectomía mecánica y hospital general con trombólisis disponible. En dicho contexto, el uso de la escala FAST-ED (mayor o igual a 4 puntos) (tabla 11) es una alternativa para la detección de ACVi por oclusión de vaso grande proximal y decisión de referencia directa a centro especializado con trombectomía mecánica. Esta escala presenta un razón de verosimilitud positiva (RV +) de 5.85(31). El GEG-Local consideró que en los pacientes con sospecha de ACVi, estos tienen una representación funcional que depende de la localización del mismo. Esta diferencia es clara cuando los infartos corresponden a la circulación posterior (arterias del territorio vertebrobasilar que irrigan el tallo encefálico, cerebelo y lóbulo occipital) frente a los de circulación anterior (arterias derivadas de las carótidas internas, que comprenden los lóbulos frontotemporoparietales); pues los primeros afectan inicialmente la funcionabilidad de los nervios craneales y la metría o coordinación; mientras que los segundos afectan funciones cerebrales más complejas como el lenguaje o habla (32). Siendo que las escalas estarían principalmente diseñadas para identificar los infartos de la circulación anterior pues estos representan el mayor porcentaje de casos (33, 34). , el GEG decidió formular un punto de BPC para que otros tipos de presentación que no sean detectados por estas escalas pero sean de alta sospecha, como pacientes con vértigo persistente, alteración del nivel de conciencia, alteración súbita de la visión, inestabilidad para la marcha derivar a centros especializados.

Caracterización clínica, tomográfica e histopatológica de pacientes con cáncer de pulmón / Clinical, tomographic and histopathological characterization of patients with lung cancer

Se realizó un estudio observacional, descriptivo y transversal de 61 pacientes con diagnóstico confirmado de cáncer de pulmón, atendidos en el Servicio de Radiología del Hospital General Docente Dr Juan Bruno Zayas Alfonso de Santiago de Cuba durante 2015, con vistas a caracterizarles según variables de interés. Los resultados se organizaron en distribuciones de frecuencias y se confeccionaron tablas de una y dos entradas para establecer algunas relaciones entre variables. En la serie predominaron el sexo masculino (55,7 por ciento), el grupo etario de 60-69 años (39,3 por ciento), el antecedente de bronquitis crónica en ambos sexos (75,4 por ciento), la tos como síntoma principal (63,9 por ciento), la localización periférica (78,7 por ciento) y el adenocarcinoma como tipo histológico (57,4 por ciento), entre otros. Al momento del diagnóstico el mayor número de afectados se encontraba en etapas avanzadas de la enfermedad, por lo que se recomienda implementar estudios a todos aquellos con riesgo de padecerla.

An observational, descriptive and cross-sectional study of 61 patients with confirmed diagnosis of lung cancer, assisted in the Radiology Service of Dr Juan Bruno Zayas Alfonso Teaching General Hospital in Santiago de Cuba was carried out during 2015, with the aim of characterizing them according to variables of interest. The results were organized in distributions of frequencies and charts of one and two entrances were made to establish some relationships among variables. In the series, the male sex (55.7 percent), the age group 60-69 years (39.3 percent), history of chronic bronchitis in both sexes (75.4 percent), cough as main symptom (63.9 percent), outlying localization (78.7 percent) and the adenocarcinoma as histological type (57.4 percent) prevailed, among others. At the moment of the diagnosis the greatest number affected patients was in advanced stages of the disease, so that it is recommended to implement studies to all those with risk of suffering it.

Pseudoaneurisma ventricular izquierdo / Left ventricular pseudoaneurysm

El pseudoaneurisma cardíaco es una entidad poco frecuente, que se produce cuando existe una rotura incompleta de la pared del corazón y el pericardio sella dicha rotura. Se desarrolla una neocavidad comunicada con la cavidad ventricular por un orificio estrecho. El objetivo del presente trabajo es reportar un caso de pseudoaneurisma ventricular izquierdo, entidad muy poco frecuente. Se presenta un paciente masculino de 69 años, con antecedentes de infarto del miocardio tres años previos al ingreso, que acude al cuerpo de guardia por dolor torácico y disnea. Se le realiza radiografía de tórax, vista póstero-anterior, donde se observa imagen radiopaca con tendencia nodular que borra el contorno cardiaco izquierdo, se complementa con ecografía transtorácica y tomografía helicoidal computarizada, se visualiza una imagen sacular por adición en la pared lateral del ventrículo izquierdo, con trombo mural en su interior, que comunicaba con este a través de cuello estrecho. Se llegó a la conclusión de que se trataba de un pseudoaneurisma ventricular izquierdo. Esta es una entidad que presenta una alta mortalidad, por lo que es necesario realizar un diagnóstico oportuno, a fin de tomar la conducta adecuada para prevenir las complicaciones(AU)

The cardiac pseudoaneurysm is a rare entity, which occurs when there is an incomplete rupture of the heart wall and the pericardium seals the rupture. A neocavity develops communicating with the ventricular cavity through a narrow orifice. The objective of this study is to report a rare case of left ventricular pseudoaneurysm. We present a 69-year-old male patient with a history of myocardial infarction three years prior to admission. The patient goes to the emergency room for chest pain and dyspnea. He underwent chest X-rays for rear-anterior view showing a radiopaque image with nodular tendency that erases the left cardiac line. Transthoracic ultrasound and computerized helical tomography are used to complement the examination. A saccular image is shown by adding to the lateral wall of the left ventricle with wall thrombus inside, a communicating narrow neck. It was concluded that it was a left ventricular pseudoaneurysm. This is an entity that presents high mortality, so it is necessary to make timely diagnosis, in order to take the appropriate medical behavior for preventing complications(AU)

Meningiomas petroclivales: estrategia quirúrgica endoscópica a propósito de dos casos / Petroclival meningioma: endoscopic approach and case report

A pesar del desarrollo de las técnicas quirúrgicas de base de cráneo, los meningiomas petroclivales constituyen un reto para el neurocirujano debido a su localización y relación con estructuras neurológicas y vasculares críticas. Se reportan 2 pacientes con diagnóstico de meningioma petroclival que recibieron tratamiento por etapas incluyendo derivación ventrículo peritoneal asistida por endoscopia para la hidrocefalia, abordaje endonasal endoscópico (AEE) extendido al ápex petroso, keyhole subtemporal y retromastoideo con remoción de la lesión. La evolución fue satisfactoria. Se concluyó que los abordajes endoscópicos y por etapas constituyen una excelente opción en el tratamiento de los meningiomas petroclivales.

In spite of the development of the skull base surgery techniques, petroclival meningiomas are a challenge for neurosurgeon due to their localization and relationship with neurovascular structures. Those are two patient with diagnostic of petroclival meningioma whom received treatment step by step included ventricle peritoneal shunt with endoscopic guide for hydrocephalus, extended endonasal approach to petrous apex, subtemporal and retrosigmoid keyhole. The endoscopic approach is an excellent option in the treatment of petroclival meningioma.

Reconstrucción mandibular postraumática / Posttraumatic mandibular reconstruction

Introducción: dentro de los factores que conducen a deformidades persistentes después de traumatismos craneofaciales, se incluye el tratamiento inicial excesivamente retardado. La reconstrucción mandibular ideal proporcionará un arco dentario sólido para articularse con el maxilar y restaurar el habla, deglución, masticación y estética. Objetivo: caracterizar un caso de reconstrucción mandibular en una deformidad postraumática mandibular. Presentación del caso: paciente femenina de 49 años que solo puede alimentarse con comida licuada a partir de un trauma craneofacial recibido seis meses atrás. Se encontró al examen físico facial asimetría con aumento de la dimensión vertical del tercio inferior de la cara con incompetencia bilabial, y al bucal que se trataba de una paciente desdentada total superior y parcial inferior rehabilitada protésicamente en la arcada maxilar, con imposibilidad para el cierre bucal y con la presencia de un escalón visible en el reborde residual a altura del 45 y por distal del 37. Se llegó al diagnóstico de una deformidad postraumática por fractura mandibular bilateral. Se valoró de conjunto con la especialidad de Prótesis, y se decidió tratamiento quirúrgico encaminado a la reconstrucción mandibular mediante abordaje cervical, refractura, reubicación mandibular con fijación de la guía oclusal y colocación de placas mandibulares de carga soportada con tornillos bicorticales. Se realizó el seguimiento por consulta externa después del alta hospitalaria. La paciente refiere estar muy conforme con su aspecto estético y con la mejoría funcional alcanzada. Conclusiones: las secuelas postraumáticas se acompañan frecuentemente de daños en tejidos blandos y duros de la región facial con diferente grado de alteración estética y funcional para el paciente. Lograr restituir estos mediante la reconstrucción facial suele ser un reto profesional que puede ser mejor enfrentado mediante el tratamiento en equipo y transdisciplinario(AU)

Introduction: overly delayed initial treatment is one the factors leading to persistent deformities after craniofacial trauma. Ideal mandibular reconstruction will create a solid dental arch which will articulate with the maxilla and restore speech, swallowing, mastication and esthetics. Objective: present a case of mandibular reconstruction of a posttraumatic mandibular deformity. Case presentation: a 49-year-old female patient can only feed herself liquid food after a craniofacial trauma undergone six months before. Physical examination revealed facial asymmetry with an increase in the vertical dimension of the lower third of the face and bilabial incompetence. Oral examination, on the other hand, revealed that the patient had a totally edentulous upper dental arch and partial prosthetic rehabilitation of the maxillary arch, impossibility of oral closure, and the presence of a visible step on the residual ridge at the 45 and distal 37. Diagnosis was a posttraumatic deformity due to bilateral mandibular fracture. Evaluation was carried out in joint coordination with the prosthesis service, and it was decided to perform surgical mandibular reconstruction by cervical approach, refracture, mandibular relocation with fixation of the occlusal guide, and placement of load bearing mandibular plates with bicortical screws. Outpatient follow-up was conducted after hospital discharge. The patient states that she is very pleased with her esthetic appearance and the functional improvement achieved. Conclusions: posttraumatic sequelae are frequently accompanied by damage to soft and hard tissues of the facial region with varying degrees of esthetic and functional alteration. Restoration by means of facial reconstruction is often a professional challenge which may be best tackled with a team, transdisciplinary therapeutic approach(AU)

Mucormicosis rinosinusal por mucor hiemalis en una paciente con leucemia mieloide aguda / Rhinosinusal mucormycosis by mucor hiemalis in a patient with acute myeloid leukemia

Se reporta un caso clínico de una paciente femenina de 41 años, con antecedentes de leucemia mieloide aguda (LMA) en remisión. Estudiada por hematología, se confirmó recaída de LMA M4. Se inició quimioterapia. La paciente evolucionó con pancitopenia severa. Presentó dos episodios de neutropenia febril, el primero fue asociado a un absceso glúteo que se trató con antibacterianos, y el segundo a compromiso rinosinusal y úlcera necrótica de punta nasal, columela, tabique, cornete inferior izquierdo y paladar duro. Debido a la clínica e imá- genes radiológicas, se sospechó mucormicosis, por lo que se realizó cirugía con debridación extensa y se inició tratamiento antimicótico con anfotericina B desoxicolato. El cultivo de tejido informó abundante desarrollo de Mucor hiemalis. Se mantuvo pancitopénica durante aproximadamente un mes, siendo diariamente evaluada por un equipo multidisciplinario. Se hicieron varios aseos quirúrgicos, en el último se encontró tejido vital. La paciente completó diez días con anfotericina B desoxicolato y posteriormente se hizo traslape a posaconazol oral. Se realizó mielograma de control que evidenció remisión completa de recaída de LMA. Se dio de alta a su domicilio al día 40 de hospitalización, con hemograma adecuado y tratamiento oral con posaconazol para completar 6 semanas en total.

We report a case of a 41-years-old female patient with a history of acute myeloid leukemia (AML) in remission. Hematology studies confirmed relapse of AML M4. Chemotherapy was started. The patient developed severe pancytopenia. She presented two episodes of febrile neutropenia, the first one was associated with a gluteal abscess that was treated with antibacterials, and the second to rhinosinusal involvement and necrotic ulcer of nasal tip, columella, septum, left inferior turbinate and hard palate. Due to clinical and radiological imaging, mucormycosis was suspected, so surgery was performed with extensive debridement and antifungal treatment with amphotericin B deoxicholate was initiated. Tissue culture reported abundant development of Mucor hiemalis. She remained pancytopenic for approximately one month, being evaluated daily by a multidisciplinary team. Several surgical were made, finding vital tissue in the last perform. The patient completed ten days with amphotericin B deoxicholate and later was overlapped to oral posaconazole. A control myelogram was performed, showing complete remission of AML. She was discharged to her home at day 40 of hospitalization, with adequate blood count and oral treatment with posaconazole to complete 6 weeks in total.

Trauma intracraneal penetrante trans-orbitario: anatomía relevante, las dinámicas del trauma y los puntos clavepara el tratamiento / Trans-orbital intracranial penetrating trauma: relevant anatomy, trauma dynamics and treatment key points

Las lesiones intracraneales penetrantes trans-orbitarias representan pocos casos de todos los Traumas Craneo-encefálicos, sin embargo, representan del 25 al 50 por ciento de todos los traumas penetrantes craneales. Este tipo de traumas trans-orbitarios se han reportado por diferentes tipos de objetos, incluyendo objetos de metal y de madera. Muchos de estos traumas intracraneales pueden pasar desapercibidos en casos donde el material que ingresa no queda expuesto posterior al trauma y cuando no se presenta lesión neurológica que requiera examinación exhaustiva adicional con neuro-imágenes.

Trans-orbital penetrating intracranial injuries represent few cases of all Traumatic Brain Injuries, although they represent between 25 to 50 percent of all penetrating brain injuries. Trans-orbital intracranial penetrating injuries have been reported caused by different types of objects, including metal and wooden objects. Many of these intracranial traumas can be dismissed, especially in those cases where the material is not exposed after the injury and there is no need of further examination with neuroimaging in absence of neurological deficit.

Vasoespasmo cerebral y déficit isquémico tardío en la hemorragia subaracnoídea aneurismática: guías para su manejo clínico / Cerebral vasospasm and delayed ischemic deficit in the aneurysmal subarachnoid hemorrhage: guidelines to its clinical management

La presente revisión del tema Vasoespasmo y Déficit Isquémico Cerebral tardío (DIT) en la Hemorragia subaracnoidea aneurismática tiene como objetivo actualizar su manejo, basado en las hipótesis mas aceptadas que se han logrado para explicar su patogénesis. Se efectúa una introducción con conceptos generales, se revisan las bases patogénicas del Vasoespasmo y se plantea su manejo, tomando en cuenta su diagnóstico, monitorización, profilaxis y manejo avanzado de acuerdo a las últimas Guías de Manejo Clínico y según medicina basada en las evidencias.

The objective of the present review on cerebral vasospasm and cerebral delayed isquemic deficit due to subarachnoid haemorrhage secondary to ruptured cerebral aneurysm, is to update their management, based on the most accepted pathophysiological hypotesis explaining their pathogenetic mechanisms. An introduction is performed presenting general concepts, review of the most recent research works explaining their pathogenesis, and the management is stated touching diagnosis, monitoring, prophylaxis, and advanced management according with the last clinical guidelines for his management using medicine based on evidences.

Validação de dois métodos de análise volumétrica e linear óssea em tomografia computadorizada multislice 3D / Validation of two methods of volumetric and linear bone analysis in 3D multislice computed tomography

O objetivo deste trabalho foi avaliar a acurácia e reprodutibilidade de medidas ósseas lineares e volumétricas através do processamento de dados obtidos por tomografia computadorizada multislice por dois softwares Amira6® e CoDiagnostiX®. O material da pesquisa foi composto de uma mandíbula seca. Foi feita uma tomada tomográfica da peça intacta e uma segunda tomada com a mandíbula adicionada de quatro enxertos em bloco de diferentes dimensões, além de quatro desgastes. Os dados obtidos foram então processados através dos dois softwares por 3 examinadores, previamente calibrados, duas vezes cada um. As medidas físicas lineares dos blocos foram obtidas com um paquímetro digital e as de volume dos blocos e desgastes pela técnica do deslocamento em água em um cilíndro milimetrado. O volume dos desgastes foi obtido por preenchimento dos mesmos com resina bisacrílica de uma moldagem feita com a mandíbula intacta sobreposta na mesma com os desgastes, estes dados foram processados apenas pelo software Amira6® que permite a sobreposição de imagens 3D. A acurácia das medidas lineares e de volume foi avaliada pela comparação com o padrão ouro através do teste-T de Student e ANOVA. Os resultados mostraram que não houve diferença estatística significante nas medidas lineares e volumétricas obtidas entre os dois softwares e quando comparados individualmente com o padrão ouro.

The aim of this study was to evaluate the accuracy and reproducibility of linear and volumetric bone measurements through data processing obtained by multislice computed tomography for two softwares: Amira6® and CoDiagnostiX®. The research material was composed of a dry mandible. A first tomography was made and then the jaw was added with four bone block grafts of different sizes and four wears were made in the chin area. The data were then processed twice using the two softwares by 3 examiners previously calibrated. Linear physical measurements of the blocks were obtained with a digital caliper and the volume of the blocks and wears by water displacement in a calibrated cylinder. The volume of each wear was obtained by filling the same with bis-acrylic composite of a matrix made with the jaw intact superimposed on it, these data were processed only by Amira6® software that allows 3D images overlap. The accuracy of linear and volumetric measurements was evaluated by comparison to the gold standard by Student T-test and ANOVA. The results showed no statistically significant difference in linear and volumetric measurements between the two softwares and individually when compared with the gold standard.

Estudio paleorradiológico y tridimensional en momias y cuerpos momificados / Paleo-radiology and three-dimensional study in mummies and mummified bodies

Estudios realizados en momias o en cuerpos momificados con técnicas convencionales y estudios de tomografía computada, revelaron patologíasmaxilofaciales tales como: atrición, pulpitis abscesos y enfermedad periodontal; además de otras enfermedades con mayor compromiso general, a saber: osteomielitis, enfermedad de Paget, defectos cráneomandibulares y traumas. Sin embargo, se observa un bajo porcentaje de caries. Para la continuidad de la vida en el más allá, revestía una importancia fundamental la conservación de loscuerpos en este mundo...

Effect of sugarcane biopolymer in vocal fold of rabbits. Comparative study with calcium hydroxyapatite

PURPOSE: To compare the inflammatory reaction caused by the injection of a sugarcane biopolymer (SCB) into the vocal fold of rabbits with that caused by calcium hydroxyapatite (CaH). METHODS: CaH (Radiesse(r)) and SCB gel were injected respectively into the right and left vocal cords of thirty rabbits. The rabbits were distributed into two equal groups and sacrificed at three and twelve weeks after injection. We then evaluated the intensity of the inflammatory reaction, plus levels of neovascularization, fibrogenesis and inflammatory changes in the vocal mucosa. RESULTS: The vocal cords injected with CaH had a stronger inflammatory reaction by giant cells in both study periods. The SCB group had a more intense inflammatory involvement of polymorphonuclear cells three weeks after injection. SCB caused a higher level of neovascularization compared with CaH three weeks after the procedure. CONCLUSION: Whereas calcium hydroxyapatite triggers a more intense and lasting inflammatory reaction mediated by giant cells, sugarcane biopolymer causes a greater response from polymorphonuclear leukocytes, as well as higher levels of vneoascularization three weeks after injection. .

Comparison of imaging modalities for detection of residual fragments and prediction of stone related events following percutaneous nephrolitotomy

Introduction Achieving stone free status (SFS) is the goal of stone surgery. In this study it is aimed to compare effectiveness of unenhanced helical computerized tomography (UHCT), KUB and ultrasonography (US) for detection of residual RFs and predicition of stone releated events following percutaneous nephrolitotomy (PNL). Materials and Methods Patients underwent PNL for radiopaque stones between November 2007 and February 2010 were followed. Patients were examined within 24-48 hours after the procedure by KUB, US and UHCT. For stone size 4 mm was accepted as cut off level of significance.Sensitivity and specificity of KUB and US for detection of RFs and value of them for prediction of stone related events were calculated. Results SFS was achieved in 95 patients (54.9%) and when cut off value of 4 mm for RFs was employed, SFS was achieved in 131 patients (75.7%). Sensitivity was 70.5% for KUB, and 52.5% for US. UHCT was shown to be significantly more efficient for detection of RFs compared to both KUB (p=0.01) and US (p=0.001). When cut off level of 4 mm employed, sensitivity of KUB and US increased to 85.7% and 57.1%. Statistical significant superiority of UHCT still remained (p value vs. KUB: 0.03 and p value vs. US: 0.008). Conclusion UHCT is the most sensitive diagnostic tool for detecting RFs after PNL. It has higher sensitivity regardless of stone size compared to KUB and US. Additionally UHCT has higher capability of predicting occurrence of stone related events. .

Detection of proximal caries using digital radiographic systems with different resolutions.

Background: Dental radiography is an important tool for detection of caries and digital radiography is the latest advancement in this regard. Spatial resolution is a characteristic of digital receptors used for describing the quality of images. Aim: This study was aimed to compare the diagnostic accuracy of two digital radiographic systems with three different resolutions for detection of noncavitated proximal caries. Settings and Design: Diagnostic accuracy. Materials and Methods: Seventy premolar teeth were mounted in 14 gypsum blocks. Digora® Optime and RVG Access were used for obtaining digital radiographs. Six observers evaluated the proximal surfaces in radiographs for each resolution in order to determine the depth of caries based on a 4‑point scale. The teeth were then histologically sectioned, and the results of histologic analysis were considered as the gold standard. Data were entered using SPSS version 18 software and the Kruskal–Wallis test was used for data analysis. P <0.05 was considered as statistically significant. Results: No significant difference was found between different resolutions for detection of proximal caries (P > 0.05). RVG access system had the highest specificity (87.7%) and Digora® Optime at high resolution had the lowest specificity (84.2%). Furthermore, Digora® Optime had higher sensitivity for detection of caries exceeding outer half of enamel. Judgment of oral radiologists for detection of the depth of caries had higher reliability than that of restorative dentistry specialists. Conclusion: The three resolutions of Digora® Optime and RVG access had similar accuracy in detection of noncavitated proximal caries.

Collateral Ventilation Quantification Using Xenon-Enhanced Dynamic Dual-Energy CT: Differences between Canine and Swine Models of Bronchial Occlusion

OBJECTIVE: The aim of this study was to evaluate whether the difference in the degree of collateral ventilation between canine and swine models of bronchial obstruction could be detected by using xenon-enhanced dynamic dual-energy CT. MATERIALS AND METHODS: Eight mongrel dogs and six pigs underwent dynamic dual-energy scanning of 64-slice dual-source CT at 12-second interval for 2-minute wash-in period (60% xenon) and at 24-second interval for 3-minute wash-out period with segmental bronchus occluded. Ventilation parameters of magnitude (A value), maximal slope, velocity (K value), and time-to-peak (TTP) enhancement were calculated from dynamic xenon maps using exponential function of Kety model. RESULTS: A larger difference in A value between parenchyma was observed in pigs than in dogs (absolute difference, -33.0 +/- 5.0 Hounsfield units [HU] vs. -2.8 +/- 7.1 HU, p = 0.001; normalized percentage difference, -79.8 +/- 1.8% vs. -5.4 +/- 16.4%, p = 0.0007). Mean maximal slopes in both periods in the occluded parenchyma only decreased in pigs (all p < 0.05). K values of both periods were not different (p = 0.892) in dogs. However, a significant (p = 0.027) difference was found in pigs in the wash-in period. TTP was delayed in the occluded parenchyma in pigs (p = 0.013) but not in dogs (p = 0.892). CONCLUSION: Xenon-ventilation CT allows the quantification of collateral ventilation and detection of differences between canine and swine models of bronchial obstruction.