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1.
An Engineered Complement Factor H Construct for Treatment of C3 Glomerulopathy.
J Am Soc Nephrol
; 29(6): 1649-1661, 2018 06.
Article
in English
| MEDLINE | ID: mdl-29588430
2.
Disease-linked mutations in factor H reveal pivotal role of cofactor activity in self-surface-selective regulation of complement activation.
J Biol Chem
; 292(32): 13345-13360, 2017 08 11.
Article
in English
| MEDLINE | ID: mdl-28637873
3.
Structural basis for sialic acid-mediated self-recognition by complement factor H.
Nat Chem Biol
; 11(1): 77-82, 2015 Jan.
Article
in English
| MEDLINE | ID: mdl-25402769
4.
Complement Evasion Mediated by Enhancement of Captured Factor H: Implications for Protection of Self-Surfaces from Complement.
J Immunol
; 195(10): 4986-98, 2015 Nov 15.
Article
in English
| MEDLINE | ID: mdl-26459349
5.
Creating functional sophistication from simple protein building blocks, exemplified by factor H and the regulators of complement activation.
Biochem Soc Trans
; 43(5): 812-8, 2015 Oct.
Article
in English
| MEDLINE | ID: mdl-26517887
6.
Tissue-specific host recognition by complement factor H is mediated by differential activities of its glycosaminoglycan-binding regions.
J Immunol
; 190(5): 2049-57, 2013 Mar 01.
Article
in English
| MEDLINE | ID: mdl-23365078
7.
Characterization of a factor H mutation that perturbs the alternative pathway of complement in a family with membranoproliferative GN.
J Am Soc Nephrol
; 25(11): 2425-33, 2014 Nov.
Article
in English
| MEDLINE | ID: mdl-24722444
8.
Combination of factor H mutation and properdin deficiency causes severe C3 glomerulonephritis.
J Am Soc Nephrol
; 24(1): 53-65, 2013 Jan.
Article
in English
| MEDLINE | ID: mdl-23204401
9.
Functional anatomy of complement factor H.
Biochemistry
; 52(23): 3949-62, 2013 Jun 11.
Article
in English
| MEDLINE | ID: mdl-23701234
10.
Solution NMR structure of the Ca2+-bound N-terminal domain of CaBP7: a regulator of golgi trafficking.
J Biol Chem
; 287(45): 38231-43, 2012 Nov 02.
Article
in English
| MEDLINE | ID: mdl-22989873
11.
Structural basis for complement factor H linked age-related macular degeneration.
J Exp Med
; 204(10): 2277-83, 2007 Oct 01.
Article
in English
| MEDLINE | ID: mdl-17893204
12.
Structural and functional characterization of the product of disease-related factor H gene conversion.
Biochemistry
; 51(9): 1874-84, 2012 Mar 06.
Article
in English
| MEDLINE | ID: mdl-22320225
13.
Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome.
Blood
; 115(2): 379-87, 2010 Jan 14.
Article
in English
| MEDLINE | ID: mdl-19861685
14.
The structure of the KlcA and ArdB proteins reveals a novel fold and antirestriction activity against Type I DNA restriction systems in vivo but not in vitro.
Nucleic Acids Res
; 38(5): 1723-37, 2010 Mar.
Article
in English
| MEDLINE | ID: mdl-20007596
15.
An Evaluation of the Complement-Regulating Activities of Human Complement Factor H (FH) Variants Associated With Age-Related Macular Degeneration.
Invest Ophthalmol Vis Sci
; 63(12): 30, 2022 11 01.
Article
in English
| MEDLINE | ID: mdl-36445700
16.
A Novel Full-Length Recombinant Human Complement Factor H (CFH; GEM103) for the Treatment of Age-Related Macular Degeneration Shows Similar In Vitro Functional Activity to Native CFH.
Curr Eye Res
; 47(7): 1087-1093, 2022 07.
Article
in English
| MEDLINE | ID: mdl-35282732
17.
Annexin-II, DNA, and histones serve as factor H ligands on the surface of apoptotic cells.
J Biol Chem
; 285(6): 3766-3776, 2010 Feb 05.
Article
in English
| MEDLINE | ID: mdl-19951950
18.
Crystallographic determination of the disease-associated T1184R variant of complement regulator factor H.
Acta Crystallogr D Biol Crystallogr
; 67(Pt 7): 593-600, 2011 Jul.
Article
in English
| MEDLINE | ID: mdl-21697597
19.
A molecular insight into complement evasion by the staphylococcal complement inhibitor protein family.
J Immunol
; 183(4): 2565-74, 2009 Aug 15.
Article
in English
| MEDLINE | ID: mdl-19625656
20.
The binding of factor H to a complex of physiological polyanions and C3b on cells is impaired in atypical hemolytic uremic syndrome.
J Immunol
; 182(11): 7009-18, 2009 Jun 01.
Article
in English
| MEDLINE | ID: mdl-19454698