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1.
Predicting clinically promising therapeutic hypotheses using tensor factorization.
BMC Bioinformatics
; 20(1): 69, 2019 Feb 08.
Article
in English
| MEDLINE | ID: mdl-30736745
2.
Systematic interrogation of diverse Omic data reveals interpretable, robust, and generalizable transcriptomic features of clinically successful therapeutic targets.
PLoS Comput Biol
; 14(5): e1006142, 2018 05.
Article
in English
| MEDLINE | ID: mdl-29782487
3.
Inhibition of p38 mitogen-activated protein kinase reduces inflammation after coronary vascular injury in humans.
Arterioscler Thromb Vasc Biol
; 30(11): 2256-63, 2010 Nov.
Article
in English
| MEDLINE | ID: mdl-20689074
4.
Network and pathway expansion of genetic disease associations identifies successful drug targets.
Sci Rep
; 10(1): 20970, 2020 12 01.
Article
in English
| MEDLINE | ID: mdl-33262371
5.
Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases.
Nat Genet
; 52(10): 1122-1131, 2020 10.
Article
in English
| MEDLINE | ID: mdl-32895551
6.
Pathway analysis of GWAS loci identifies novel drug targets and repurposing opportunities.
Drug Discov Today
; 24(6): 1232-1236, 2019 06.
Article
in English
| MEDLINE | ID: mdl-30935985
7.
Preclinical evaluation of EPHX2 inhibition as a novel treatment for inflammatory bowel disease.
PLoS One
; 14(4): e0215033, 2019.
Article
in English
| MEDLINE | ID: mdl-31002701
8.
Predominance of a proinflammatory phenotype in monocyte-derived macrophages from subjects with low plasma HDL-cholesterol.
Arterioscler Thromb Vasc Biol
; 27(5): 1115-22, 2007 May.
Article
in English
| MEDLINE | ID: mdl-17322100
9.
Chfr regulates a mitotic stress pathway through its RING-finger domain with ubiquitin ligase activity.
Cancer Res
; 62(6): 1797-801, 2002 Mar 15.
Article
in English
| MEDLINE | ID: mdl-11912157
10.
Impact of genetically supported target selection on R&D productivity.
Nat Rev Drug Discov
; 15(9): 596-597, 2016 09 12.
Article
in English
| MEDLINE | ID: mdl-28184040
11.
Systematic Analysis of Drug Targets Confirms Expression in Disease-Relevant Tissues.
Sci Rep
; 6: 36205, 2016 11 08.
Article
in English
| MEDLINE | ID: mdl-27824084
12.
Combined Analysis of Phenotypic and Target-Based Screening in Assay Networks.
J Biomol Screen
; 19(5): 782-90, 2014 Jun.
Article
in English
| MEDLINE | ID: mdl-24563424
13.
Trial watch: Impact of genetically supported target selection on R&D productivity.
Nat Rev Drug Discov
; 15(9): 596-597, 2016 Aug 30.
Article
in English
| MEDLINE | ID: mdl-27573226
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