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1.
Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules.
Mol Cell
; 82(9): 1643-1659.e10, 2022 05 05.
Article
in English
| MEDLINE | ID: mdl-35334231
2.
The structure of NAD+ consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations.
J Biol Chem
; 299(11): 105290, 2023 11.
Article
in English
| MEDLINE | ID: mdl-37758001
3.
Multiple domain interfaces mediate SARM1 autoinhibition.
Proc Natl Acad Sci U S A
; 118(4)2021 01 26.
Article
in English
| MEDLINE | ID: mdl-33468661
4.
High-throughput single-cell functional elucidation of neurodevelopmental disease-associated genes reveals convergent mechanisms altering neuronal differentiation.
Genome Res
; 30(9): 1317-1331, 2020 09.
Article
in English
| MEDLINE | ID: mdl-32887689
5.
Cell-autonomous expression of the acid hydrolase galactocerebrosidase.
Proc Natl Acad Sci U S A
; 117(16): 9032-9041, 2020 04 21.
Article
in English
| MEDLINE | ID: mdl-32253319
6.
A phytobacterial TIR domain effector manipulates NAD+ to promote virulence.
New Phytol
; 233(2): 890-904, 2022 01.
Article
in English
| MEDLINE | ID: mdl-34657283
7.
Rapid and Extraction-Free Detection of SARS-CoV-2 from Saliva by Colorimetric Reverse-Transcription Loop-Mediated Isothermal Amplification.
Clin Chem
; 67(2): 415-424, 2021 01 30.
Article
in English
| MEDLINE | ID: mdl-33098427
8.
Palmitoylation enables MAPK-dependent proteostasis of axon survival factors.
Proc Natl Acad Sci U S A
; 115(37): E8746-E8754, 2018 09 11.
Article
in English
| MEDLINE | ID: mdl-30150401
9.
Schwann cell O-GlcNAcylation promotes peripheral nerve remyelination via attenuation of the AP-1 transcription factor JUN.
Proc Natl Acad Sci U S A
; 115(31): 8019-8024, 2018 07 31.
Article
in English
| MEDLINE | ID: mdl-30012597
10.
HSP90 is a chaperone for DLK and is required for axon injury signaling.
Proc Natl Acad Sci U S A
; 115(42): E9899-E9908, 2018 10 16.
Article
in English
| MEDLINE | ID: mdl-30275300
11.
Disrupting insulin signaling in Schwann cells impairs myelination and induces a sensory neuropathy.
Glia
; 68(5): 963-978, 2020 05.
Article
in English
| MEDLINE | ID: mdl-31758725
12.
mTORC1 promotes proliferation of immature Schwann cells and myelin growth of differentiated Schwann cells.
Proc Natl Acad Sci U S A
; 114(21): E4261-E4270, 2017 05 23.
Article
in English
| MEDLINE | ID: mdl-28484008
13.
Dysregulation of NAD+ Metabolism Induces a Schwann Cell Dedifferentiation Program.
J Neurosci
; 38(29): 6546-6562, 2018 07 18.
Article
in English
| MEDLINE | ID: mdl-29921717
14.
Abnormal Microglia and Enhanced Inflammation-Related Gene Transcription in Mice with Conditional Deletion of Ctcf in Camk2a-Cre-Expressing Neurons.
J Neurosci
; 38(1): 200-219, 2018 01 03.
Article
in English
| MEDLINE | ID: mdl-29133437
15.
SARM1-specific motifs in the TIR domain enable NAD+ loss and regulate injury-induced SARM1 activation.
Proc Natl Acad Sci U S A
; 113(41): E6271-E6280, 2016 10 11.
Article
in English
| MEDLINE | ID: mdl-27671644
16.
An NAD+-dependent transcriptional program governs self-renewal and radiation resistance in glioblastoma.
Proc Natl Acad Sci U S A
; 113(51): E8247-E8256, 2016 12 20.
Article
in English
| MEDLINE | ID: mdl-27930300
17.
Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.
Genome Res
; 25(7): 948-57, 2015 Jul.
Article
in English
| MEDLINE | ID: mdl-25917818
18.
Feeding the brain and nurturing the mind: Linking nutrition and the gut microbiota to brain development.
Proc Natl Acad Sci U S A
; 112(46): 14105-12, 2015 Nov 17.
Article
in English
| MEDLINE | ID: mdl-26578751
19.
Schwann Cell O-GlcNAc Glycosylation Is Required for Myelin Maintenance and Axon Integrity.
J Neurosci
; 36(37): 9633-46, 2016 09 14.
Article
in English
| MEDLINE | ID: mdl-27629714
20.
TMEM184b Promotes Axon Degeneration and Neuromuscular Junction Maintenance.
J Neurosci
; 36(17): 4681-9, 2016 04 27.
Article
in English
| MEDLINE | ID: mdl-27122027