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1.
Generation of a human induced pluripotent stem cell-based model for tauopathies combining three microtubule-associated protein TAU mutations which displays several phenotypes linked to neurodegeneration.
Alzheimers Dement
; 14(10): 1261-1280, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30036493
2.
Human TRPA1 is intrinsically cold- and chemosensitive with and without its N-terminal ankyrin repeat domain.
Proc Natl Acad Sci U S A
; 111(47): 16901-6, 2014 Nov 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-25389312
3.
Different ligands of the TRPV3 cation channel cause distinct conformational changes as revealed by intrinsic tryptophan fluorescence quenching.
J Biol Chem
; 290(20): 12964-74, 2015 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25829496
4.
Functional characterization of p7 viroporin from hepatitis C virus produced in a cell-free expression system.
Protein Expr Purif
; 118: 83-91, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26477501
5.
Cell-free expression of a functional pore-only sodium channel.
Protein Expr Purif
; 111: 42-7, 2015 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-25770647
6.
Antibiotic translocation through porins studied in planar lipid bilayers using parallel platforms.
Analyst
; 140(14): 4874-81, 2015 Jul 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-25834843
7.
Voltage-gated sodium channel (NaV) protein dissection creates a set of functional pore-only proteins.
Proc Natl Acad Sci U S A
; 108(30): 12313-8, 2011 Jul 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-21746903
8.
Development of a new hazard scoring system in primary neuronal cell cultures for drug-induced acute neuronal toxicity identification in early drug discovery.
Front Pharmacol
; 15: 1308547, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38873414
9.
Regulation of human microglial gene expression and function via RNAase-H active antisense oligonucleotides in vivo in Alzheimer's disease.
Mol Neurodegener
; 19(1): 37, 2024 Apr 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-38654375
10.
Green fluorescent protein changes the conductance of connexin 43 (Cx43) hemichannels reconstituted in planar lipid bilayers.
J Biol Chem
; 287(4): 2877-86, 2012 Jan 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-22139870
11.
The Potential Mechanisms behind Loperamide-Induced Cardiac Arrhythmias Associated with Human Abuse and Extreme Overdose.
Biomolecules
; 13(9)2023 09 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37759755
12.
High-Throughput Screening Assay for Detecting Drug-Induced Changes in Synchronized Neuronal Oscillations and Potential Seizure Risk Based on Ca2+ Fluorescence Measurements in Human Induced Pluripotent Stem Cell (hiPSC)-Derived Neuronal 2D and 3D Cultures.
Cells
; 12(6)2023 03 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-36980298
13.
Design, synthesis and functional analysis of dansylated polytheonamide mimic: an artificial peptide ion channel.
J Am Chem Soc
; 134(34): 14011-8, 2012 Aug 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-22861006
14.
Identifying Acute Cardiac Hazard in Early Drug Discovery Using a Calcium Transient High-Throughput Assay in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Front Physiol
; 13: 838435, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35547580
15.
The human TRPA1 intrinsic cold and heat sensitivity involves separate channel structures beyond the N-ARD domain.
Nat Commun
; 13(1): 6113, 2022 10 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-36253390
16.
Is the forming of neuronal network activity in human-induced pluripotent stem cells important for the detection of drug-induced seizure risks?
Eur J Pharmacol
; 931: 175189, 2022 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35987255
17.
Seizure-induced Torsades de pointes:In a canine drug-induced long-QT1 model.
J Pharmacol Toxicol Methods
; 111: 107086, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34119674
18.
Development of a fully human assay combining NGN2-inducible neurons co-cultured with iPSC-derived astrocytes amenable for electrophysiological studies.
Stem Cell Res
; 54: 102386, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-34229210
19.
SOX9-induced Generation of Functional Astrocytes Supporting Neuronal Maturation in an All-human System.
Stem Cell Rev Rep
; 17(5): 1855-1873, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-33982246
20.
The structure of the antimicrobial human cathelicidin LL-37 shows oligomerization and channel formation in the presence of membrane mimics.
Sci Rep
; 10(1): 17356, 2020 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33060695