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1.
Biomed Phys Eng Express ; 9(2)2023 02 01.
Artículo en Inglés | MEDLINE | ID: mdl-36689772

RESUMEN

Achieving fast coincidence timing resolution (CTR) is an important issue in clinical time-of-flight positron emission tomography (TOF-PET) to improve the reconstructed image quality. One of the major factors affecting the CTR is the crystal surface treatment, which is often parameterized as surface roughness. However, previous studies on the crystal surface treatment optimization had two limitations of crystal-by-crystal variation and worse CTR over 200 ps. Here, we report the effects of the crystal surface treatment on the performance of a 20 mm long fast-LGSO crystal based TOF detector by tracking the same crystals in the sub-180 ps CTR regime. The light collection efficiency (LCE), energy resolution (ER) and CTR of the TOF detector were evaluated with six different crystal surface treatments of chemically polished (C.P), C.P half side roughened (1/2S) treatment, and then the C.P one side roughened (1S) treatment, mechanically polished (M.P) treatment, M.P 1/2S treatment, and M.P 1S treatment. The four lateral surfaces of each crystal were wrapped by using enhanced specular reflector film while the top surface was covered by using Teflon tape. The bottom surface of the crystal was optically coupled to a silicon photomultiplier. The timing and energy signals were extracted by using a custom-made high-frequency readout circuit, and then digitized by using a waveform digitizer. All the experimental conditions were same except the crystal surface treatment. Among the six different crystal surface treatments, the M.P 1S would be the optimal crystal surface treatment which balanced enhancements in the CTR (165 ± 3 ps) and ER (10.5 ± 0.5%). Unlike the M.P 1S, the C.P 1S did not enhance the CTR and ER. Hence, the C.P without roughening would be the second-best optimal crystal surface treatment which balanced the CTR (169 ± 3 ps) and ER (10.5 ± 0.5%).


Asunto(s)
Tomografía de Emisión de Positrones , Conteo por Cintilación , Tomografía de Emisión de Positrones/métodos , Fotones
2.
Biomed Phys Eng Express ; 8(2)2022 02 28.
Artículo en Inglés | MEDLINE | ID: mdl-35180713

RESUMEN

Coincidence timing resolution (CTR) is an important parameter in clinical positron emission tomography (PET) scanners to increase the signal-to-noise ratio of PET images by using time-of-flight (TOF) information. Lutetium (Lu) based scintillators are often used for TOF-PET systems. However, the self-radiation of Lu-based scintillators may influence the image quality for ultra-low activity PET imaging. Recently, a gadolinium fine aluminum gallate (Ce:GFAG) scintillation crystal that features a fast decay time (∼55 ns) and no self-radiation was developed. The present study aimed at optimizing the GFAG crystal surface treatment to enhance both CTR and energy resolution (ER). The TOF-PET detector consisted of a GFAG crystal (3.0 × 3.0 × 20 mm3) and a SiPM with an effective area of 3.0 × 3.0 mm2. The timing and energy signals were extracted using a high-frequency SiPM readout circuit and then were digitized using a CAMAC DAQ system. The CTR and ER were evaluated with nine different crystal surface treatments such as partial saw-cut and chemical polishing and the 1-side saw-cut was the best choice among the treatments. The respective CTR and ER of 202 ± 2 ps and 9.5 ± 0.1% were obtained with the 1-side saw-cut; the other 5-side mechanically polished GFAG crystals had respective values which were 18 ps (9.0%) and 1.3% better than those of the all-side mechanically polished GFAG crystal. The chemically polished GFAG crystals also offered enhanced CTR and ER of about 17 ps (8.2%) and 2.1%, respectively, over the mechanically polished GFAG crystals.


Asunto(s)
Fotones , Tomografía de Emisión de Positrones , Aluminio , Lutecio , Tomografía de Emisión de Positrones/métodos , Relación Señal-Ruido
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