RESUMO
Hemosuccus pancreaticus is a rare cause of upper gastrointestinal hemorrhage. It is mainly produced by bleeding from a pseudoaneurysm that runs through the pancreatic duct and flows into the second portion of the duodenum. This article presents a case of a patient in the sixth decade of life with upper gastrointestinal bleeding who underwent a computed tomography (CT) scan of the abdomen finding a pseudoaneurysm of the gastroduodenal artery. Subsequently, angiography confirmed active bleeding from the pseudoaneurysm, requiring endovascular treatment by interventional radiology, which was successful with the resolution of the bleeding. In this article, our aim is to expand the information on this pathology and to promote the optimization of diagnostic tests for the timely treatment of this rare disease that is potentially life-threatening.
RESUMO
La leucoencefalopatía megaencefálica con quistes subcorticales (MLC) o enfermedad de Van der Knaap es un trastorno genético infrecuente. La mutación en el gen MLC1 se ha demostrado como la responsable de esta alteración. La disminución en la expresión de la proteína codificada causa vacuolización en los astrocitos y alteración de la homeostasis del agua y los electrolitos. Los casos presentados permiten ilustrar los hallazgos imaginológicos característicos de esta entidad, debido a que el diagnóstico se fundamenta en las imágenes en resonancia magnética (RM).
Megalencephalic leukoencephalopathy with subcortical cysts (MLC) or Van der Knaap disease is a rare genetic disease. The MLC1 mutation genes participate in the pathogenesis. The decreased expression of the encoded protein in astrocytes causes vacuolation, impaired water, and electrolyte homeostasis. We report two cases and illustrate the typical imaging features. The diagnosis of this disease is based on magnetic resonance imaging findings (MRI).
