RESUMO
OBJECTIVE: As a measure of the quality of care provided to patients in the intensive care unit, comparison of nosocomial infection rates with those of the National Nosocomial Infection surveillance was completed during a 3-year observation period. DESIGN: The study design was a prospective study during 3 years between 1993 and 1995. During that period, patients at the medical/surgical and neurosurgical intensive care units and the high-risk nursery were surveyed for nosocomial infections. Device use, bloodstream infection, urinary tract infection, and ventilator-associated pneumonia nosocomial infection rates were calculated and compared with the National Nosocomial Infection Surveillance published rates for the same period. SETTING: The study setting was the medical/surgical intensive care unit, the neurosurgical intensive care unit, and the high-risk nursery at the Jordan University Hospital. RESULTS: Overall infection rates were 17.2 per 100 patients in the medical/surgical intensive care unit, 14.2 to 18.5 per 100 patients in the neurosurgical intensive care unit, and 13.4 to 73.5 per 100 patients in the high-risk nursery. When compared with the weight of the infants, these rates were 61.9 to 94 per 100 in infants weighing <1500 g, 26 to 30.8 per 100 patients in infants weighing >1500 g to 2500 g, and 11.7 to 14.4 per 100 in infants weighing >2500 g. Whereas device use was moderate, bloodstream infection and ventilator-associated pneumonia rates were >90th percentile for National Nosocomial Infection Surveillance in the high-risk nursery, and urinary tract infection was >90th percentile in the medical/surgical and neurosurgical intensive care units. Nosocomial infections at the intensive care units in developing countries need further investigation and control.
Assuntos
Infecção Hospitalar/epidemiologia , Hospitais Universitários/estatística & dados numéricos , Unidades de Terapia Intensiva/estatística & dados numéricos , Avaliação de Resultados em Cuidados de Saúde , Adolescente , Adulto , Distribuição por Idade , Criança , Pré-Escolar , Infecção Hospitalar/diagnóstico , Países em Desenvolvimento , Feminino , Pesquisas sobre Atenção à Saúde , Humanos , Lactente , Jordânia/epidemiologia , Masculino , Valores de Referência , Distribuição por Sexo , Análise de SobrevidaRESUMO
OBJECTIVE: To study the epidemiology of needlestick and sharp injuries in a university hospital in a developing country, Jordan. METHODS: A prospective study was undertaken of all needlestick and sharp injuries among workers at the Jordan University Hospital between 1993 and 1995. Health care workers were asked to report in person to the infection-control team to verify the incident and to respond to a questionnaire. Blood was obtained from patients and health care workers immediately and from the health care workers 6 months later for hepatitis B virus, hepatitis C virus, and HIV testing. RESULTS: During the 3-year period, 248 health care workers had needlestick and sharp injuries. Of these, 34.6% were staff nurses, 19%, environmental workers, 15.7%, interns, 11.7%, residents, 8.5%, practical nurses, and 6% were technicians. The incidence density was highest for the interns followed by staff nurses and environmental workers. Of incidents, 22.6% occurred during blood drawing, 11.3% during placing intravenous lines, 8.5% during administration of medication, 11% during recapping the needle, 10.5% during needle disposal, 12.5% during garbage collection, and 5% were caused by a neglected needle. Only 117 patients were identified; 36 of 62 of these had positive results for hepatitis B surface antigen, and 8 of 13 for hepatitis C virus. CONCLUSION: Needlestick and sharp injuries occur frequently in developing countries. Safer disposal facilities and routine hepatitis B vaccine should be adopted.
Assuntos
Países em Desenvolvimento , Hospitais Universitários , Ferimentos Penetrantes Produzidos por Agulha/etiologia , Recursos Humanos em Hospital , Humanos , Incidência , Controle de Infecções , Jordânia , Ferimentos Penetrantes Produzidos por Agulha/epidemiologia , Ferimentos Penetrantes Produzidos por Agulha/prevenção & controle , Estudos Prospectivos , Fatores de Risco , Inquéritos e QuestionáriosRESUMO
Until recently measles was a very severe illness of infancy and early childhood in Jordan. Incidence rates were estimated to be as high as 500 to 1000/100,000 and case fatality rates were as high as 10%. Since 1981 mandatory and routine vaccination was introduced by the Ministry of Health. Because infants accounted for the most severe cases and almost all mortality, measles vaccine was given at 9 months of age. No booster doses were recommended. Since 1981 there has been a steady shift in the age distribution of cases toward the older age group. In recent years children > 5 years of age accounted for > 60% of cases. Commensurate with that the mortality rate has decreased to almost nil in recent years. There is also evidence of a marked decrease of inpatient admission of measles cases to one of the largest hospitals, the Jordan University Hospital. Despite high immunization rates in excess of 88%, however, outbreaks of measles continue to occur. To evaluate the impact of measles vaccination on outbreaks, a study in one village in 1987 showed that there was almost no protective efficacy in children > 5 years of age (relative risk 0.80 and confidence interval 0.06 to 0.67 vs. relative risk 0.73 and confidence interval 0.54 to 1.15). Although the current measles immunization strategy has decreased the mortality and morbidity rates, we propose that the continuing occurrence of outbreaks necessitates the addition of a booster dose after 15 months of age.(ABSTRACT TRUNCATED AT 250 WORDS)
Assuntos
Vacina contra Sarampo/imunologia , Sarampo/epidemiologia , Fatores Etários , Criança , Pré-Escolar , Surtos de Doenças/prevenção & controle , Feminino , Humanos , Lactente , Jordânia , Masculino , Sarampo/mortalidade , Sarampo/prevenção & controle , PrevalênciaRESUMO
OBJECTIVE: To describe an outbreak of salmonella food poisoning that probably was due to contamination of mashed potatoes by a foodhandler, which occurred despite a policy for routine surveillance stool cultures of kitchen employees. DESIGN: A case control study of 223 individuals who ate the lunch meal on September 23, 1989, at the Jordan University Hospital (JUH) cafeteria. SETTING: Tertiary care university hospital in Amman, the capital of Jordan. PATIENTS: Individuals who developed loose stool or vomiting 6 to 72 hours after eating the lunch meal of September 23, 1989, at the JUH cafeteria. RESULTS: Of 619 individuals, 183 fit the case definition (attack rate, 19.6%); 150 were employees, 26 were inpatients, and seven were visitors. Twelve other employees became sick 4 to 6 days later and probably were infected secondarily. The incubation period ranged from 16 to 72 hours in 183 instances. Symptoms included diarrhea (88%), fever (71%), abdominal pain (74%), dehydration (34%), and bloody stool (5%). Eighty-four were hospitalized. Cultures of eight food items were negative, but stool culture on 90 of 180 patients and 11 of 61 kitchen employees yielded Salmonella enteritidis group D. A cohort study of 223 individuals revealed a food-specific attack rate of 72% for the steak and potato meal and 18% for the rice and meat meal (RR, 4; CI95, 2.62 to 6.24; P < 0.01). Stratified analysis of the steak and potato meal revealed that the potatoes were implicated most strongly (RR, 1.93; CI95, 1.42 to 2.64; P < 0.01). Cultures were obtained from all kitchen employees, and 11 of 61 grew Salmonella enteritidis group D. One asymptomatic, culture-positive employee prepared the mashed potatoes on September 23. All of these employees had negative stool cultures 3 months earlier. CONCLUSION: This outbreak probably was caused by massive contamination of mashed potatoes by the contaminated hands of the foodhandler. Routine stool culture of foodhandlers is not cost-effective and should not be used as a substitute for health education and proper hygienic practices.
Assuntos
Surtos de Doenças/estatística & dados numéricos , Manipulação de Alimentos , Serviço Hospitalar de Nutrição , Intoxicação Alimentar por Salmonella/epidemiologia , Técnicas Bacteriológicas , Estudos de Casos e Controles , Fezes/microbiologia , Microbiologia de Alimentos , Hospitais Universitários , Humanos , Jordânia , Recursos Humanos em Hospital , Vigilância da População , Intoxicação Alimentar por Salmonella/transmissão , Salmonella enteritidis/isolamento & purificaçãoRESUMO
Treatment of childhood brucellosis is controversial and is currently dependent on inclusion of aminoglycoside antibiotics which are both costly and potentially toxic. Hence an alternate mode of therapy preferably dependent exclusively on oral agents is desirable because this decreases medical cost. In this study we prospectively treated 113 children with a combination of two oral agents, trimethoprim-sulfamethoxazole (10 to 12 mg/kg trimethoprim, 50 to 60 mg/kg sulfamethoxazole and rifampin 15 to 20 mg/kg in two divided doses for 6 weeks. The treatment was well-tolerated and all patients responded by defervescence of fever and resolution of all symptoms within 1 to 3 weeks. Relapse after 6 months occurred in four children all of whom responded to repeat therapy by the same agents. We conclude that the combination of trimethoprim-sulfamethoxazole and rifampin is both cost-effective and safe for the treatment of childhood brucellosis.