1.
Am J Respir Crit Care Med
; 203(11): e35-e36, 2021 06 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33617755
Assuntos
Articulação Atlantoccipital , Atlas Cervical , Luxações Articulares/diagnóstico por imagem , Apneia do Sono Tipo Central/diagnóstico , Apneia do Sono Tipo Central/etiologia , Síndrome de Wolf-Hirschhorn/complicações , Pré-Escolar , Feminino , Humanos , Luxações Articulares/complicações , Síndrome de Wolf-Hirschhorn/diagnóstico por imagem
2.
Sleep Med Clin
; 15(4): 485-495, 2020 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33131659
RESUMO
Individuals with Duchenne muscular dystrophy (DMD) have evolving sleep and respiratory pathophysiology over their lifetimes. Across the lifespan of DMD, various sleep-related breathing disorders (SRBD) have been described, including obstructive sleep apnea, central sleep apnea, and nocturnal hypoventilation. In addition to SRBD, individuals with DMD can be affected by insomnia, chronic pain and other factors interfering with sleep quality, and daytime somnolence. The natural progression of DMD pathophysiology has changed with the introduction of therapies for downstream pathologic pathways and will continue to evolve with the development of therapies that target function and expression of dystrophin.