Psychiatric symptoms, burnout and associated factors in psychiatry residents.

INTRODUCTION: Mental health in training physicians is a growing issue. The aim of this study was to investigate emotional distress in psychiatry residents. METHOD: This web-based survey evaluated 115 (62%) psychiatry residents in training in the Brazilian State of Rio Grande do Sul. The DSM-5 Self-Rated Level 1 Cross-Cutting Symptom Measure-Adult, the Patient Health Questionnaire-2, the Alcohol Use Disorders Identification Test-concise, and the Maslach Burnout Inventory were all administered. Linear regression models were estimated with burnout dimensions as dependent variables. RESULT: Positive screening rates were 53% for anxiety, 35.7% for somatization, 16.5% for depression, and 7% for suicidal ideation. Half of the male residents were at risk of alcohol abuse and dependence. Regarding burnout, 60% met criteria for emotional exhaustion, 54.8% for depersonalization, and 33% for low personal accomplishment. The most consistent risk factors were the nature of the relationships with preceptors, relations to the institutions themselves, age, and the quality of relationships with family. CONCLUSION: Besides disconcerting rates of psychiatric symptoms, the study revealed that characteristics of the workplace (i.e., the nature of relationships with preceptors and relations to the institution) can be regarded as potential targets for development of interventions aimed at improving mental health during training periods.

Psychiatric symptoms, burnout and associated factors in psychiatry residents

Abstract Introduction Mental health in training physicians is a growing issue. The aim of this study was to investigate emotional distress in psychiatry residents. Method This web-based survey evaluated 115 (62%) psychiatry residents in training in the Brazilian State of Rio Grande do Sul. The DSM-5 Self-Rated Level 1 Cross-Cutting Symptom Measure-Adult, the Patient Health Questionnaire-2, the Alcohol Use Disorders Identification Test-concise, and the Maslach Burnout Inventory were all administered. Linear regression models were estimated with burnout dimensions as dependent variables. Result Positive screening rates were 53% for anxiety, 35.7% for somatization, 16.5% for depression, and 7% for suicidal ideation. Half of the male residents were at risk of alcohol abuse and dependence. Regarding burnout, 60% met criteria for emotional exhaustion, 54.8% for depersonalization, and 33% for low personal accomplishment. The most consistent risk factors were the nature of the relationships with preceptors, relations to the institutions themselves, age, and the quality of relationships with family. Conclusion Besides disconcerting rates of psychiatric symptoms, the study revealed that characteristics of the workplace (i.e., the nature of relationships with preceptors and relations to the institution) can be regarded as potential targets for development of interventions aimed at improving mental health during training periods.

Patterns of high-risk drinking among medical students: A web-based survey with machine learning.

BACKGROUND: Prior studies have found increased rates of alcohol consumption among physicians and medical students. The present study aims to build machine learning (ML) models to identify patterns of high-risk drinking (HRD), including alcohol use disorder, within this population. METHODS: We analyzed data collected through a web-based survey among Brazilian medical students. Variables included sociodemographic data, personal information, university status, and mental health. Stratification for HRD was carried out based on the AUDIT-C scores. Three ML algorithms were used to build classifiers to predict HRD among medical students: elastic net regularization, random forest, and artificial neural networks. Model interpretation techniques were adopted to assess the most influential predictors for models' decisions, which represent potential factors associated with HRD. RESULTS: A total of 4840 medical students were included in the study. The prevalence of HRD was 53.03%. The three ML models built were able to distinguish individuals with HRD from low-risk drinking (LRD) with very similar performance. The average AUC scores in the cross-validation procedure were around 0.72, and this performance was replicated in the test set. The most important features for the ML models were the use of tobacco and cannabis, monthly family income, marital status, sexual orientation, and physical activities. CONCLUSIONS: This study proposes that ML models may serve as tools for initial screening of students regarding their susceptibility for at-risk drinking or alcohol use disorder. In addition, we identified several key factors associated with HRD that could be further investigated and explored for preventive and assistance measures.

Loneliness, but not social distancing, is associated with the incidence of suicidal ideation during the COVID-19 outbreak: a longitudinal study.

BACKGROUND: Although social distancing is necessary to decrease COVID-19 dissemination, it might also be associated with suicidal ideation. Therefore, we analyzed the impact of social distancing and loneliness in suicidal ideation. METHODS: We performed two waves of a snowball sample, web-based survey in Brazil (W1: from May 6th to June 6th, 2020; W2: from June 6th to July 6th, 2020). We assessed whether risk factors related to social relationships (loneliness, living alone, not leaving home, and the number of days practicing social distancing) at W1 were associated with suicidal ideation at W1 and W2 using multiple regression models. Analyses were adjusted for sociodemographic, mental health, and lifestyle variables. RESULTS: A total of 1,674 (18-75 years old; 86.5% females) were included in our longitudinal sample. Living alone (OR: 1.16; 95%CI = 1.03 - 1.30; p=0.015), number of days practicing social distancing (OR: 1.002; 95%CI = 1.000 - 1.004; p=0.027), and loneliness (OR: 1.49; 95%CI = 1.32 - 1.68; p<0.001) were associated with suicidal ideation in the cross-sectional analysis of W1. Only loneliness (OR= 2.12; 95%CI = 1.06 - 4.24; p = 0.033) remained significant as a risk factor to suicidal ideation in the longitudinal analysis between both waves. LIMITATION: Snowball, convenience sample design limits outcome estimates. Assessments were not objectively performed. CONCLUSION: Loneliness was consistently associated with the incidence of suicidal ideation, while other variables, such as living alone, not leaving home, and the number of days practicing social distancing, were not. Measures to overcome loneliness are therefore necessary to reduce suicidal ideation during pandemics.

[Communication and Mental Health: Characteristics related to empathy in primary care physicians in Chapecó, Santa Catarina, Brazil]. / Comunicación y salud mental: características relacionadas con la empatía en médicas y médicos del primer nivel de atención en Chapecó, Santa Catarina, Brasil.

In Brazil, the provision of mental health care in primary care centers has gained strategic importance, as it ensures that users will be able to attend these services within their communities, and empathy is a key aspect in the development of the doctor-patient relationship. The aim of this study was to identify characteristics related to empathy in physicians who work in primary care centers and who provide care to individuals with mental disorders. Qualitative research was carried out in 2016, based on semi-structured interviews with eight general and family physicians. Material from the interviews was analyzed using content analysis techniques and three categories emerged: empathy in the active listening of the physician, strategies that allow for better patient care, and the mobilization of emotions. The use of empathy is intrinsically linked to the resolutive capacity of care, and the characteristics identified were active listening, resource management, and the development of methods to overcome the structural obstacles of daily routines.

En Brasil, el cuidado en salud mental en los centros de atención primaria se tornó estratégico, dado que garantiza que el usuario asista en su territorio, y la empatía es de gran importancia en el desarrollo de la relación médico-paciente. El objetivo de este estudio fue identificar características relacionadas con la empatía en médicas y médicos que trabajan en el primer nivel y atienden a personas con sufrimiento mental. Se realizó una investigación cualitativa, en 2016, con entrevistas semiestructuradas a ocho médicas y médicos generalistas y de familia. Los relatos se analizaron con la técnica de análisis de contenido y se identificaron tres categorías: empatía en la escucha activa del médico, estrategias que permitan una mejor atención del paciente y movilización de sentimientos. El uso de la empatía está intrínsecamente relacionado con la resolutividad de la atención y las características encontradas fueron la utilización de la escucha activa, el manejo de recursos y el desarrollo de métodos para superar trabas estructurales del cotidiano.

Comunicación y salud mental: características relacionadas con la empatía en médicas y médicos del primer nivel de atención en Chapecó, Santa Catarina, Brasil / Communication and Mental Health: Characteristics related to empathy in primary care physicians in Chapecó, Santa Catarina, Brazil

RESUMEN En Brasil, el cuidado en salud mental en los centros de atención primaria se tornó estratégico, dado que garantiza que el usuario asista en su territorio, y la empatía es de gran importancia en el desarrollo de la relación médico-paciente. El objetivo de este estudio fue identificar características relacionadas con la empatía en médicas y médicos que trabajan en el primer nivel y atienden a personas con sufrimiento mental. Se realizó una investigación cualitativa, en 2016, con entrevistas semiestructuradas a ocho médicas y médicos generalistas y de familia. Los relatos se analizaron con la técnica de análisis de contenido y se identificaron tres categorías: empatía en la escucha activa del médico, estrategias que permitan una mejor atención del paciente y movilización de sentimientos. El uso de la empatía está intrínsecamente relacionado con la resolutividad de la atención y las características encontradas fueron la utilización de la escucha activa, el manejo de recursos y el desarrollo de métodos para superar trabas estructurales del cotidiano.

ABSTRACT In Brazil, the provision of mental health care in primary care centers has gained strategic importance, as it ensures that users will be able to attend these services within their communities, and empathy is a key aspect in the development of the doctor-patient relationship. The aim of this study was to identify characteristics related to empathy in physicians who work in primary care centers and who provide care to individuals with mental disorders. Qualitative research was carried out in 2016, based on semi-structured interviews with eight general and family physicians. Material from the interviews was analyzed using content analysis techniques and three categories emerged: empathy in the active listening of the physician, strategies that allow for better patient care, and the mobilization of emotions. The use of empathy is intrinsically linked to the resolutive capacity of care, and the characteristics identified were active listening, resource management, and the development of methods to overcome the structural obstacles of daily routines.

Neuron-glia Interaction as a Possible Pathophysiological Mechanism of Bipolar Disorder.

Accumulating evidence has shown the importance of glial cells in the neurobiology of bipolar disorder. Activated microglia and inflammatory cytokines have been pointed out as potential biomarkers of bipolar disorder. Indeed, recent studies have shown that bipolar disorder involves microglial activation in the hippocampus and alterations in peripheral cytokines, suggesting a potential link between neuroinflammation and peripheral toxicity. These abnormalities may also be the biological underpinnings of outcomes related to neuroprogression, such as cognitive impairment and brain changes. Additionally, astrocytes may have a role in the progression of bipolar disorder, as these cells amplify inflammatory response and maintain glutamate homeostasis, preventing excitotoxicity. The present review aims to discuss neuron-glia interactions and their role in the pathophysiology and treatment of bipolar disorder.

Prevenção ao uso de álcool e outras drogas e tratamento na Atenção Primária à Saúde em um município do Sul do Brasil / Prevention of alcohol and other drugs use and treatment in primary health care in a southern Brazilian city

Este estudo teve por objetivo investigar as ações de prevenção e tratamento a usuários de álcool e outras drogas na Atenção Primária à Saúde (APS). Trata-se de uma pesquisa qualitativa realizada com 12 profissionais da Estratégia Saúde da Família que contam com o apoio matricial em saúde mental, em uma cidade da serra gaúcha. Foi utilizada a análise de conteúdo, na modalidade temática. Os resultados evidenciam a importância do tratamento não só do usuário, mas de toda a família; os resultados também apontaram a importância do vínculo estabelecido entre as equipes de referência e os usuários; a necessidade de investir e qualificar o apoio matricial para dar suporte às equipes da Estratégia de Saúde da Família nas questões referentes ao uso de substâncias psicoativas.

This study aimed to investigate prevention actions treatment to alcohol and other drugs users in Primary Health Care. It is a qualitative survey carried out with 12 professionals who count with mental health matrix support at the Family Health Strategy. It was using the thematic content analysis. Results showed not only the importance of the treatment for the user, but also for his family. Results also showed the importance of the bond established between the reference team and the user; and the need to investigate and qualify the matrix support to help Family Health Strategy teams regarding issues related to the use of psychoactive substances.

The epidemiological profile of a middle-aged population with low back pain in southern Brazil.

STUDY DESIGN: Cross-sectional study. OBJECTIVE: To assess the prevalence and the general characteristics of low back pain (LBP) in a middle-aged population living in southern Brazil. SUMMARY OF BACKGROUND DATA: LBP is a widespread musculoskeletal condition. It is the main cause of disability in developed countries. It is necessary and relevant to study the risk factors for LBP to plan preventative action. A cross-sectional study of a middle-aged population in the South of Brazil was designed to look at the prevalence and general characteristics of LBP. METHODS: A cross-sectional study was developed in a city located in southern Brazil. Data were collected from 1005 individuals at randomized public locations. A protocol was designed to evaluate the general characteristics of the population: age, sex, level of education, socioeconomic status, body mass index, occupation, smoking, physical activity, anxiety, and depression. After the initial evaluation, the individuals were asked if they had had low back pain at least once in their lifetime. Those who answered "Yes" continued the questionnaire that evaluated pain intensity, characteristics, and related disability. After the entire group was analyzed (N = 1005), a separate study was performed on the participants younger than 40 years (N = 701). RESULTS: The mean age was 33.74 years (±14.76) and 61.6% of the participants were females. Seventy-two percent of the participants had had LBP at least once in their lives. The mean of visual analogue scale intensity of pain was 4.51 (±2.27). The prevalence of female sex (P = 0.006) and anxiety (P < 0.001) was higher in those with LBP. In the group younger than 40 years, the prevalence of LBP was 69.7% and anxiety (P < 0.001) was the only factor related to LBP. CONCLUSION: Low back pain is a highly prevalent condition in a middle-aged population living in southern Brazil. Higher levels of anxiety and female sex were related to this condition in all groups, but when it was analyzed in the participants younger than 40 years, anxiety was the only significant variable related with LBP. LEVEL OF EVIDENCE: 3.

How can we teach them about neurotrauma prevention? Prospective and randomized "Pense Bem-Caxias do Sul" study with multiple interventions in preteens and adolescents.

UNLABELLED: OBJECT.: A previous study published by the authors showed that a single intervention could not change the baseline attitudes toward neurotrauma prevention. The present study was designed to evaluate the effectiveness of multiple interventions in modifying knowledge and attitudes for the prevention of neurotrauma in Brazilian preteens and adolescents. METHODS: In a randomized controlled trial, fifth-year primary school (PS) and second-year high school (HS) students were divided into a control and 2 intervention (single/multiple) groups. The study was conducted in the following 8 stages: T1, questionnaire to measure baseline characteristics; T2, lecture on trauma prevention; T3, reapplying the questionnaire used in T1; T4, Traffic Department intervention; T5, a play about trauma and its consequences; T6, Fire Department intervention; T7, Emergency Medical Service intervention; and T8, reapplying the questionnaire used in T1 and T3. Positive answers were considered those affirming the use of safety devices "always or sometimes" and negative as "never" using safety devices. RESULTS: The sample consisted of 535 students. Regarding attitudes, students in all groups at any stage of measurement showed protective behavior more than 95% of the time about seat belt use. There were only differences between attitudes in PS and HS students on T8 assessment concerning the use of safety equipment on bikes in the multiple-intervention group and concerning the use of safety equipment on skateboards and rollerblades in single- and multiple-intervention groups. These differences were caused mainly by the reduction in positive answers by the HS group, rather than by the increase in positive or protective answers by the PS group. However, there was no difference when the control and intervention groups were compared, independent of the attitudes or the student groups studied. The most important reason for not using protective devices was the belief that they would not get hurt. CONCLUSIONS: Multiple and different types of educational interventions, such as lectures, scenes from plays about trauma and its consequences, traffic and fire department intervention, and medical emergency intervention directed to preteens and adolescents from public and private schools did not modify most students' attitudes toward injury prevention. Clinical trial registration no: U1111-1121-0192 (National System of Ethics and Research in Brazil).

Experimental Model of Spinal Cord Injury (SCI) in rats: management guidelines / Modelo Experimental de Lesão Medular (SCI) em ratos: diretrizes de manejo / Modelo Experimental de Lesión de Médula Espinal (SCI) en ratas: guías de manejo

Surgical experiments with laboratory animals are necessary for medical research. These studies aim to clarify the mechanism of disease, investigate the action and efficacy of new drugs or biological markers, as well as develop and enhance new therapies and apply new techniques. Regarding the models of spinal cord injury (SCI), there are several different methods that address the handling of the animals, especially concerning the use of analgesics, antibiotics and pre- and postoperative management. The lack of uniformity and standardization among the studies does not allow the understanding of the model of SCI or the proper handling of the paraplegic animals, hampering the adequate interpretation and comparison of results. The goal of this study is to establish a standard protocol on the handling of animals subjected to experimental models of SCI.

Experimentações cirúrgicas em nível laboratorial com o uso de animais são necessárias para o desenvolvimento da pesquisa médica. Estes estudos têm o objetivo de identificar o mecanismo das doenças, pesquisar a ação e eficácia de novos medicamentos ou marcadores biológicos, além de desenvolver e aprimorar novas terapêuticas. Em relação aos modelos experimentais relacionados à lesão raquimedular, há diversas metodologias descritas sobres o manejo desses animais, especialmente em relação ao uso de analgésicos, antibióticos e manejo pré e pós operatórios. Essa variedade metodológica resulta na falta de uniformidade e padronização entre os estudos, prejudicando a interpretação adequada e a comparação entre os resultados. Diante deste cenário, este estudo tem objetivo de estabelecer um protocolo padrão sobre o manejo dos ratos submetidos a modelos experimentais de trauma raquimedular.

La realización de experimentos quirúrgicos con animales de laboratorio son necesarios para la investigación médica. Estos estudios tienen por objeto aclarar el mecanismo de las enfermedades, investigar la acción de nuevos medicamentos y marcadores biológicos, así como desarrollar y mejorar nuevas terapias y aplicar nuevas técnicas. En cuanto a los modelos animales de lesión de la médula espinal (SCI), existen varios métodos diferentes que abordan el cuidado de estos animales, especialmente en relación con el uso de analgésicos, antibióticos y manejo pre y post operatorio. La falta de uniformidad y estandarización entre los estudios no permite la comprensión del modelo de SCI o el manejo adecuado del animal parapléjico, lo que dificulta la interpretación y comparación adecuada de los resultados. El objetivo de este estudio es establece un protocolo estándar de manejo de animales sometidos a modelos experimentales de SCI.

Sintomas depressivos e suas características em pacientes submetidos a hemodiálise / Depressive symptoms and their characteristics in patients undergoing hemodialysis

A depressão é uma condição presente em 20% dos portadores de doenças crônicas, estando associada à incapacitação funcional e comprometimento da saúde física. A doença renal crônica faz parte desse escopo, com prevalência de 405 pacientes por milhão de habitantes submetidos a hemodiálise no Brasil. Objetiva-se avaliar prevalência de sintomatologia depressiva e suas características em pacientes sob tratamento dialítico. Métodos: Estudo transversal, realizado entre junho e agosto de 2010, incluindo os pacientes submetidos a hemodiálise no Hospital Geral de Caxias do Sul, que preencheram os critérios de inclusão. Procedeu-se a aplicação de instrumentos de coleta de dados. O ponto de corte para depressão foi de 16 pontos no Inventário de Depressão de Beck. O estudo foi aprovado por Comitê de Ética em Pesquisa. Resultados: A amostra foi constituída por 64 pacientes. A média de idade foi de 53,66 ± 15,82 anos; 51,7% eram do sexo feminino. A prevalência de depressão foi de 44,8%. Os pacientes com IDB < 16 apresentaram escore médio de 7,23 ± 3,5; já aqueles com IDB > 16 apresentaram média de 26,43 ± 9,35 (p < 0,001). Os pacientes que necessitavam cuidador apresentaram maiores índices de depressão (p< 0,001). Nos pacientes com IDB > 16 os fatores mais influentes foram sono, cansaço e incapacidade de tomar decisões. Conclusão: A prevalência de depressão nos pacientes em hemodiálise é alta. Os pacientes que necessitam de cuidadores apresentam maior escore no IDB. Alterações do sono, cansaço e incapacidade de tomar decisões são os principais fatores para o humor depressivo.

Depression is a condition present in 20% of patients with chronic diseases and is associated with functional disability and impaired physical health. Chronic kidney disease is part of this scope, with an estimated prevalence of 405 patients per million undergoing hemodialysis in Brazil. The objective of this study was to evaluate the prevalence of depressive symptoms and their characteristics in patients on dialysis. Methods: A cross-sectional study conducted between June and August 2010, including patients undergoing hemodialysis at the General Hospital of Caxias do Sul, who met the inclusion criteria. The data collection instruments (questionnaire, Mini Mental State Examination and the Beck Depression Inventory–BDI) were administered individually during a hemodialysis session. The cut-off point for depression was 16 points in the BDI. Results: We studied 64 patients. The mean age was 53.66 ± 15.82 years, 51.7% were females. The prevalence of depression was 44.8. Patients with BDI<16 had a mean score of 7.23 ± 3.5, whereas those with BDI>16 had an average of 26.43 ± 9.35 (p <0.001). Patients who needed caregivers had higher levels of depression (p <0.001). In patients with BDI>16, the most influent factors were sleep, fatigue and inability to make decisions. Conclusion: The prevalence of depression in hemodialysis patients is high. Patients who need caregivers had higher scores on the BDI. Sleep disorders, fatigue and inability to make decisions are the main factors for depressed mood.