1.
FEMS Microbiol Lett
; 129(2-3): 129-33, 1995 Jun 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-7607393
RESUMO
A new sulfated, cyclic depsipeptide, called cyanopeptolin S, from Microcystis sp. was isolated from a water bloom in the Auensee/Leipzig (Germany). The depsipeptide had a relative molecular mass of 925 and contained L-arginine, L-threonine, L-isoleucine, N-methyl-L-phenylalanine, a L-glutamic acid-delta-aldehyde ring system and a sulfated D-configurated glyceric acid as a side chain. The structure was elucidated by means of two-dimensional 1H and 13C nuclear magnetic resonance spectroscopy, fast atom bombardment mass spectroscopy. Fourier transformed infrared spectroscopy and combined gas-liquid chromatography/mass spectrometry. Cyanopeptolin S inhibited trypsin with an IC50 < or = 0.2 micrograms ml-1.
Assuntos
Proteínas de Bactérias/química , Microcystis/química , Peptídeos Cíclicos/isolamento & purificação , Proteínas de Bactérias/isolamento & purificação , Depsipeptídeos , Água Doce , Estrutura Secundária de Proteína , Sulfatos/química
2.
Helv Chim Acta
; 59(4): 1075-92, 1976.
Artigo
em Alemão
| MEDLINE
| ID: mdl-950308